Motif ID: E2f7

Z-value: 1.242


Transcription factors associated with E2f7:

Gene SymbolEntrez IDGene Name
E2f7 ENSMUSG00000020185.10 E2f7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f7mm10_v2_chr10_+_110745433_110745572-0.156.2e-01Click!


Activity profile for motif E2f7.

activity profile for motif E2f7


Sorted Z-values histogram for motif E2f7

Sorted Z-values for motif E2f7



Network of associatons between targets according to the STRING database.



First level regulatory network of E2f7

PNG image of the network

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Top targets:


Showing 1 to 20 of 106 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_3013140 8.723 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr9_+_3037111 7.913 ENSMUST00000177969.1
 Gm10715
predicted gene 10715
chr9_+_3025417 6.894 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr9_+_3017408 5.947 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr9_+_3015654 5.907 ENSMUST00000099050.3
 Gm10720
predicted gene 10720
chr7_-_142578139 1.168 ENSMUST00000136359.1
 H19
H19 fetal liver mRNA
chr8_+_72319033 1.145 ENSMUST00000067912.7
 Klf2
Kruppel-like factor 2 (lung)
chr1_-_191183244 1.117 ENSMUST00000027941.8
 Atf3
activating transcription factor 3
chr7_+_35802593 0.967 ENSMUST00000052454.2
 E130304I02Rik
RIKEN cDNA E130304I02 gene
chr3_-_144202300 0.941 ENSMUST00000121796.1
ENSMUST00000121112.1
 Lmo4

LIM domain only 4

chr19_-_10881677 0.682 ENSMUST00000128835.1
 Tmem109
transmembrane protein 109
chr5_+_130448801 0.603 ENSMUST00000111288.2
 Caln1
calneuron 1
chr10_+_91082940 0.546 ENSMUST00000020150.3
 Ikbip
IKBKB interacting protein
chr3_+_60501252 0.496 ENSMUST00000099087.2
 Mbnl1
muscleblind-like 1 (Drosophila)
chr7_+_44816364 0.432 ENSMUST00000118125.1
 Il4i1
interleukin 4 induced 1
chr2_+_18672384 0.428 ENSMUST00000171845.1
ENSMUST00000061158.4
 Commd3

COMM domain containing 3

chr15_+_79030874 0.420 ENSMUST00000171999.1
ENSMUST00000006544.7
 Gcat

glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)

chr12_+_11265867 0.416 ENSMUST00000020931.5
 Smc6
structural maintenance of chromosomes 6
chr19_-_10881723 0.394 ENSMUST00000144681.1
 Tmem109
transmembrane protein 109
chr17_-_35516780 0.392 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
 Tcf19


transcription factor 19



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 1.2 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.3 1.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 1.1 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.1 0.9 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.2 0.7 GO:0071139 resolution of recombination intermediates(GO:0071139)
0.1 0.4 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.4 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.4 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.1 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.4 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.4 GO:0043486 histone exchange(GO:0043486)
0.0 0.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 0.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.2 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.8 GO:0005844 polysome(GO:0005844)
0.0 0.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.4 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.4 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613) Flemming body(GO:0090543)

Gene overrepresentation in molecular_function category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.5 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.4 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.4 GO:0019808 polyamine binding(GO:0019808)
0.1 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0070883 importin-alpha family protein binding(GO:0061676) pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)