Motif ID: E2f8

Z-value: 1.251


Transcription factors associated with E2f8:

Gene SymbolEntrez IDGene Name
E2f8 ENSMUSG00000046179.11 E2f8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f8mm10_v2_chr7_-_48881596_488816190.723.5e-03Click!


Activity profile for motif E2f8.

activity profile for motif E2f8


Sorted Z-values histogram for motif E2f8

Sorted Z-values for motif E2f8



Network of associatons between targets according to the STRING database.



First level regulatory network of E2f8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_101785252 7.010 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
 Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr1_-_128359610 3.695 ENSMUST00000027601.4
 Mcm6
minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chr6_+_21215472 3.660 ENSMUST00000081542.5
 Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr11_+_26387194 2.900 ENSMUST00000109509.1
ENSMUST00000136830.1
 Fancl

Fanconi anemia, complementation group L

chr8_+_40926220 2.864 ENSMUST00000034004.9
 Pdgfrl
platelet-derived growth factor receptor-like
chr2_-_155945282 2.678 ENSMUST00000040162.2
 Gdf5
growth differentiation factor 5
chr10_-_21160925 2.613 ENSMUST00000020158.6
 Myb
myeloblastosis oncogene
chr16_-_46496955 2.223 ENSMUST00000023335.6
ENSMUST00000023334.8
 Pvrl3

poliovirus receptor-related 3

chr11_-_89302545 2.125 ENSMUST00000061728.3
 Nog
noggin
chr16_-_46496772 2.057 ENSMUST00000149901.1
ENSMUST00000096052.2
 Pvrl3

poliovirus receptor-related 3

chr8_+_75109528 1.922 ENSMUST00000164309.1
 Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr15_-_76090013 1.850 ENSMUST00000019516.4
 Nrbp2
nuclear receptor binding protein 2
chr2_-_34913976 1.779 ENSMUST00000028232.3
 Phf19
PHD finger protein 19
chr2_+_145785980 1.721 ENSMUST00000110005.1
ENSMUST00000094480.4
 Rin2

Ras and Rab interactor 2

chr5_+_137787769 1.639 ENSMUST00000035852.7
 Zcwpw1
zinc finger, CW type with PWWP domain 1
chr4_+_132768325 1.163 ENSMUST00000102561.4
 Rpa2
replication protein A2
chr9_+_100643605 1.097 ENSMUST00000041418.6
 Stag1
stromal antigen 1
chr16_-_18811615 1.092 ENSMUST00000096990.3
 Cdc45
cell division cycle 45
chr9_-_36726374 1.088 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
 Chek1


checkpoint kinase 1


chr16_+_20733104 1.051 ENSMUST00000115423.1
ENSMUST00000007171.6
 Chrd

chordin

chr7_-_48881596 1.011 ENSMUST00000119223.1
 E2f8
E2F transcription factor 8
chr7_+_102065485 0.999 ENSMUST00000106950.1
ENSMUST00000146450.1
 Trpc2

transient receptor potential cation channel, subfamily C, member 2

chr5_+_123749696 0.985 ENSMUST00000031366.7
 Kntc1
kinetochore associated 1
chr7_-_48881032 0.983 ENSMUST00000058745.8
 E2f8
E2F transcription factor 8
chr7_+_102065713 0.928 ENSMUST00000094129.2
ENSMUST00000094130.2
ENSMUST00000084843.3
 Trpc2


transient receptor potential cation channel, subfamily C, member 2


chr5_-_137684665 0.870 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
 Agfg2


ArfGAP with FG repeats 2


chr15_+_55557399 0.806 ENSMUST00000022998.7
 Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr2_+_163054682 0.797 ENSMUST00000018005.3
 Mybl2
myeloblastosis oncogene-like 2
chr2_-_154569720 0.779 ENSMUST00000000894.5
 E2f1
E2F transcription factor 1
chr16_+_18248866 0.762 ENSMUST00000115640.1
ENSMUST00000140206.1
 Trmt2a

TRM2 tRNA methyltransferase 2A

chr6_+_38551786 0.701 ENSMUST00000161227.1
 Luc7l2
LUC7-like 2 (S. cerevisiae)
chr15_+_78926720 0.685 ENSMUST00000089377.5
 Lgals1
lectin, galactose binding, soluble 1
chr2_-_84743655 0.664 ENSMUST00000181711.1
 Gm19426
predicted gene, 19426
chr17_+_56040350 0.648 ENSMUST00000002914.8
 Chaf1a
chromatin assembly factor 1, subunit A (p150)
chr6_-_94700137 0.647 ENSMUST00000101126.2
ENSMUST00000032105.4
 Lrig1

leucine-rich repeats and immunoglobulin-like domains 1

chr7_+_110122299 0.608 ENSMUST00000033326.8
 Wee1
WEE 1 homolog 1 (S. pombe)
chr10_+_128015157 0.577 ENSMUST00000178041.1
ENSMUST00000026461.7
 Prim1

DNA primase, p49 subunit

chr2_-_154569845 0.573 ENSMUST00000103145.4
 E2f1
E2F transcription factor 1
chr6_+_125039760 0.562 ENSMUST00000140131.1
ENSMUST00000032480.7
 Ing4

inhibitor of growth family, member 4

chr2_-_91236967 0.549 ENSMUST00000028696.4
 Ddb2
damage specific DNA binding protein 2
chr7_-_27337667 0.533 ENSMUST00000038618.6
ENSMUST00000108369.2
 Ltbp4

latent transforming growth factor beta binding protein 4

chr3_-_127553233 0.524 ENSMUST00000029588.5
 Larp7
La ribonucleoprotein domain family, member 7
chr6_-_87851011 0.519 ENSMUST00000113617.1
 Cnbp
cellular nucleic acid binding protein
chr10_+_42860348 0.501 ENSMUST00000063063.7
 Scml4
sex comb on midleg-like 4 (Drosophila)
chr16_+_18248961 0.487 ENSMUST00000100099.3
 Trmt2a
TRM2 tRNA methyltransferase 2A
chr17_+_33909409 0.480 ENSMUST00000173028.1
ENSMUST00000079421.7
 Daxx

Fas death domain-associated protein

chr9_+_100643448 0.475 ENSMUST00000146312.1
ENSMUST00000129269.1
 Stag1

stromal antigen 1

chr16_+_10835046 0.475 ENSMUST00000037913.8
 Rmi2
RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chr11_+_98907801 0.454 ENSMUST00000092706.6
 Cdc6
cell division cycle 6
chr17_+_35236556 0.433 ENSMUST00000068261.8
 Atp6v1g2
ATPase, H+ transporting, lysosomal V1 subunit G2
chr11_+_77462325 0.419 ENSMUST00000102493.1
 Coro6
coronin 6
chr13_-_66852017 0.390 ENSMUST00000059329.6
 Gm17449
predicted gene, 17449
chr17_+_33909481 0.358 ENSMUST00000173626.1
ENSMUST00000174541.1
 Daxx

Fas death domain-associated protein

chr16_-_18248697 0.333 ENSMUST00000115645.3
 Ranbp1
RAN binding protein 1
chr7_-_44548733 0.332 ENSMUST00000145956.1
ENSMUST00000049343.8
 Pold1

polymerase (DNA directed), delta 1, catalytic subunit

chr18_-_9726670 0.329 ENSMUST00000171339.1
 Gm17430
predicted gene, 17430
chr17_+_33909577 0.321 ENSMUST00000170075.2
 Daxx
Fas death domain-associated protein
chr13_+_94875600 0.308 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr1_+_42229726 0.306 ENSMUST00000066196.1
 Gm9915
predicted gene 9915
chr5_+_150673739 0.303 ENSMUST00000016569.4
ENSMUST00000038900.8
 Pds5b

PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)

chr5_-_33652296 0.297 ENSMUST00000151081.1
ENSMUST00000101354.3
 Slbp

stem-loop binding protein

chr3_+_108186332 0.291 ENSMUST00000050909.6
ENSMUST00000106659.2
ENSMUST00000106656.1
ENSMUST00000106661.2
 Amigo1



adhesion molecule with Ig like domain 1



chr13_-_66851513 0.284 ENSMUST00000169322.1
 Gm17404
predicted gene, 17404
chrX_+_153498202 0.278 ENSMUST00000060714.8
 Ubqln2
ubiquilin 2
chr11_+_79993062 0.247 ENSMUST00000017692.8
ENSMUST00000163272.1
 Suz12

suppressor of zeste 12 homolog (Drosophila)

chr4_-_129189646 0.244 ENSMUST00000106059.1
 S100pbp
S100P binding protein
chr19_+_4756557 0.244 ENSMUST00000036744.7
 Rbm4b
RNA binding motif protein 4B
chrX_+_73716577 0.237 ENSMUST00000002084.7
 Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chr2_-_91236877 0.232 ENSMUST00000111352.1
 Ddb2
damage specific DNA binding protein 2
chr9_+_22003035 0.227 ENSMUST00000115331.2
ENSMUST00000003493.7
 Prkcsh

protein kinase C substrate 80K-H

chr5_-_123749393 0.222 ENSMUST00000057795.5
ENSMUST00000111515.1
ENSMUST00000182309.1
 Rsrc2


arginine/serine-rich coiled-coil 2


chr5_-_123749371 0.221 ENSMUST00000182955.1
ENSMUST00000182489.1
ENSMUST00000050827.7
 Rsrc2


arginine/serine-rich coiled-coil 2


chr4_-_129189512 0.210 ENSMUST00000117965.1
ENSMUST00000106061.2
ENSMUST00000072431.6
 S100pbp


S100P binding protein


chr10_+_84917616 0.171 ENSMUST00000038523.7
ENSMUST00000095385.3
 Ric8b

resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)

chr4_-_129189600 0.166 ENSMUST00000117497.1
ENSMUST00000117350.1
 S100pbp

S100P binding protein

chr15_-_55557748 0.153 ENSMUST00000172387.1
 Mrpl13
mitochondrial ribosomal protein L13
chr17_-_35235755 0.127 ENSMUST00000048994.6
 Nfkbil1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1
chr9_+_100643755 0.124 ENSMUST00000133388.1
 Stag1
stromal antigen 1
chr7_-_115824699 0.123 ENSMUST00000169129.1
 Sox6
SRY-box containing gene 6
chr15_+_55557575 0.107 ENSMUST00000170046.1
 Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chrX_-_73716145 0.078 ENSMUST00000002091.5
 Bcap31
B cell receptor associated protein 31
chr10_+_116301374 0.073 ENSMUST00000092167.5
 Ptprb
protein tyrosine phosphatase, receptor type, B
chr17_+_56303321 0.069 ENSMUST00000001258.8
 Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr8_-_109737714 0.066 ENSMUST00000093162.3
 Atxn1l
ataxin 1-like
chr10_+_19356558 0.064 ENSMUST00000053225.5
 Olig3
oligodendrocyte transcription factor 3
chr7_-_128740471 0.061 ENSMUST00000119081.1
ENSMUST00000057557.7
 Mcmbp

MCM (minichromosome maintenance deficient) binding protein

chrX_-_70477170 0.058 ENSMUST00000101506.3
ENSMUST00000114630.2
 BC023829

cDNA sequence BC023829

chr4_+_129189760 0.043 ENSMUST00000106054.2
ENSMUST00000001365.2
 Yars

tyrosyl-tRNA synthetase

chr5_+_135187251 0.041 ENSMUST00000002825.5
 Baz1b
bromodomain adjacent to zinc finger domain, 1B
chr6_+_108783059 0.035 ENSMUST00000032196.6
 Arl8b
ADP-ribosylation factor-like 8B
chrX_+_73716712 0.017 ENSMUST00000114461.2
 Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chr2_+_24949747 0.009 ENSMUST00000028350.3
 Zmynd19
zinc finger, MYND domain containing 19

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.0 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.7 2.0 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.5 2.7 GO:0060591 chondroblast differentiation(GO:0060591)
0.5 2.1 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.5 1.4 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.4 1.9 GO:0002121 inter-male aggressive behavior(GO:0002121) response to pheromone(GO:0019236)
0.4 1.1 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.3 1.8 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 1.4 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.2 0.6 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 1.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2 0.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 2.6 GO:0045624 positive regulation of T-helper cell differentiation(GO:0045624)
0.2 0.9 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.2 2.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 3.7 GO:0045475 locomotor rhythm(GO:0045475)
0.1 1.2 GO:0030578 PML body organization(GO:0030578)
0.1 0.7 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 2.4 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.8 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.6 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 1.2 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.4 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.5 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 2.9 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.2 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 1.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.3 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.8 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.0 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.3 1.0 GO:1990423 RZZ complex(GO:1990423)
0.3 4.3 GO:0042555 MCM complex(GO:0042555)
0.3 1.4 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 2.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 0.6 GO:0033186 CAF-1 complex(GO:0033186)
0.2 0.8 GO:0031523 Myb complex(GO:0031523)
0.1 3.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 1.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.6 GO:0030894 replisome(GO:0030894)
0.1 1.9 GO:0032590 dendrite membrane(GO:0032590)
0.1 1.2 GO:0001741 XY body(GO:0001741)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.3 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.0 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.7 2.6 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.4 2.7 GO:0036122 BMP binding(GO:0036122)
0.4 1.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 0.7 GO:0005534 galactose binding(GO:0005534)
0.3 2.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.1 GO:0045545 syndecan binding(GO:0045545)
0.2 1.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 0.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.6 GO:0052630 CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.1 0.3 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.1 0.6 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 3.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.3 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 1.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 2.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.9 GO:0003684 damaged DNA binding(GO:0003684)
0.0 2.7 GO:0019955 cytokine binding(GO:0019955)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.2 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.0 5.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 2.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.0 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 3.1 GO:0005096 GTPase activator activity(GO:0005096)