Motif ID: Ebf1

Z-value: 1.470


Transcription factors associated with Ebf1:

Gene SymbolEntrez IDGene Name
Ebf1 ENSMUSG00000078561.3 Ebf1
Ebf1 ENSMUSG00000057098.8 Ebf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ebf1mm10_v2_chr11_+_44617310_446173360.563.7e-02Click!


Activity profile for motif Ebf1.

activity profile for motif Ebf1


Sorted Z-values histogram for motif Ebf1

Sorted Z-values for motif Ebf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Ebf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_156204998 3.309 ENSMUST00000015628.3
 Fam163a
family with sequence similarity 163, member A
chr2_-_25469742 3.278 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr2_-_25470031 2.887 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chr1_+_167598450 2.427 ENSMUST00000111386.1
ENSMUST00000111384.1
 Rxrg

retinoid X receptor gamma

chr18_+_61105561 2.421 ENSMUST00000025523.6
 Csf1r
colony stimulating factor 1 receptor
chr7_-_45103747 2.140 ENSMUST00000003512.7
 Fcgrt
Fc receptor, IgG, alpha chain transporter
chr11_-_116110211 1.986 ENSMUST00000106441.1
ENSMUST00000021120.5
 Trim47

tripartite motif-containing 47

chr2_-_26246707 1.960 ENSMUST00000166349.1
 C030048H21Rik
RIKEN cDNA C030048H21 gene
chr16_+_92498122 1.946 ENSMUST00000023670.3
 Clic6
chloride intracellular channel 6
chr4_-_136898803 1.918 ENSMUST00000046285.5
 C1qa
complement component 1, q subcomponent, alpha polypeptide
chr4_-_136892867 1.912 ENSMUST00000046332.5
 C1qc
complement component 1, q subcomponent, C chain
chr17_-_34000257 1.896 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
 H2-K1




histocompatibility 2, K1, K region




chr10_+_112271123 1.879 ENSMUST00000092175.2
 Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr2_+_22622183 1.816 ENSMUST00000028123.3
 Gad2
glutamic acid decarboxylase 2
chr8_+_12395287 1.814 ENSMUST00000180353.1
 Sox1
SRY-box containing gene 1
chr2_+_71529085 1.806 ENSMUST00000152711.1
 Dlx1
distal-less homeobox 1
chr2_+_130295148 1.734 ENSMUST00000110288.2
 Ebf4
early B cell factor 4
chr2_+_71528657 1.685 ENSMUST00000126400.1
 Dlx1
distal-less homeobox 1
chr16_+_18776839 1.683 ENSMUST00000043577.1
 Cldn5
claudin 5
chr11_-_101785252 1.641 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
 Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 606 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 6.7 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.2 3.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 3.7 GO:0019882 antigen processing and presentation(GO:0019882)
1.2 3.5 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.6 3.3 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.1 3.2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.8 3.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.4 3.1 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
1.0 2.9 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.7 2.9 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.3 2.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.3 2.7 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.2 2.7 GO:0032060 bleb assembly(GO:0032060)
0.4 2.4 GO:0072224 metanephric glomerulus development(GO:0072224)
0.3 2.4 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.4 2.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.3 2.2 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 2.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.7 2.1 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 2.1 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 235 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.7 GO:0005581 collagen trimer(GO:0005581)
0.0 5.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 4.0 GO:0005667 transcription factor complex(GO:0005667)
0.3 3.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 3.3 GO:0005605 basal lamina(GO:0005605)
0.1 3.2 GO:0005604 basement membrane(GO:0005604)
1.0 3.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 3.1 GO:0034707 chloride channel complex(GO:0034707)
0.5 2.9 GO:0061689 tricellular tight junction(GO:0061689)
0.2 2.9 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.2 2.6 GO:0005922 connexon complex(GO:0005922)
0.0 2.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.8 2.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 2.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.1 GO:0060077 inhibitory synapse(GO:0060077)
0.4 2.0 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 2.0 GO:0031091 platelet alpha granule(GO:0031091)
0.0 2.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.3 1.9 GO:0043256 laminin complex(GO:0043256)
0.3 1.9 GO:0000796 condensin complex(GO:0000796)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 380 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 6.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 5.1 GO:0019955 cytokine binding(GO:0019955)
0.3 4.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.4 4.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 3.8 GO:0005179 hormone activity(GO:0005179)
0.3 3.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.8 3.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 3.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 3.0 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 2.9 GO:0005178 integrin binding(GO:0005178)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.7 GO:0045296 cadherin binding(GO:0045296)
0.1 2.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.6 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.2 2.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 2.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 2.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.4 2.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 2.1 GO:0031418 L-ascorbic acid binding(GO:0031418)