Motif ID: Ebf3

Z-value: 1.155


Transcription factors associated with Ebf3:

Gene SymbolEntrez IDGene Name
Ebf3 ENSMUSG00000010476.7 Ebf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ebf3mm10_v2_chr7_-_137314394_137314445-0.107.3e-01Click!


Activity profile for motif Ebf3.

activity profile for motif Ebf3


Sorted Z-values histogram for motif Ebf3

Sorted Z-values for motif Ebf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Ebf3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_123982799 4.905 ENSMUST00000106437.1
 Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr2_-_118703963 3.527 ENSMUST00000104937.1
 Ankrd63
ankyrin repeat domain 63
chr15_-_66812593 3.074 ENSMUST00000100572.3
 Sla
src-like adaptor
chr12_-_31713873 2.377 ENSMUST00000057783.4
ENSMUST00000174480.2
ENSMUST00000176710.1
 Gpr22


G protein-coupled receptor 22


chr15_-_45114926 2.373 ENSMUST00000022967.5
 Kcnv1
potassium channel, subfamily V, member 1
chr3_+_102735202 2.104 ENSMUST00000119902.1
 Tspan2
tetraspanin 2
chr5_+_117781017 2.067 ENSMUST00000138579.2
 Nos1
nitric oxide synthase 1, neuronal
chr7_+_62376979 1.935 ENSMUST00000080403.5
 Magel2
melanoma antigen, family L, 2
chr9_-_64022043 1.786 ENSMUST00000041029.5
 Smad6
SMAD family member 6
chr19_+_58728887 1.690 ENSMUST00000048644.5
 Pnliprp1
pancreatic lipase related protein 1
chr5_-_24601961 1.635 ENSMUST00000030791.7
 Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr11_+_117308135 1.632 ENSMUST00000153668.1
 Sept9
septin 9
chr9_-_97018823 1.616 ENSMUST00000055433.4
 Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr1_-_154725920 1.611 ENSMUST00000004214.8
 Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr9_-_110743653 1.489 ENSMUST00000166716.1
 Pth1r
parathyroid hormone 1 receptor
chr4_-_149676043 1.321 ENSMUST00000118704.1
 Pik3cd
phosphatidylinositol 3-kinase catalytic delta polypeptide
chr1_-_193370225 1.212 ENSMUST00000169907.1
 Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr3_+_26331150 1.205 ENSMUST00000099182.2
 A830092H15Rik
RIKEN cDNA A830092H15 gene
chr6_+_58831748 1.204 ENSMUST00000126292.1
ENSMUST00000031823.5
 Herc3

hect domain and RLD 3

chr19_+_43440404 1.167 ENSMUST00000165311.1
 Cnnm1
cyclin M1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 125 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.7 2.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.5 2.1 GO:1901204 positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.1 1.9 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.4 1.8 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.2 1.7 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.5 1.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.3 1.6 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.1 1.6 GO:0001765 membrane raft assembly(GO:0001765)
0.1 1.6 GO:0010107 potassium ion import(GO:0010107)
0.0 1.6 GO:0010950 positive regulation of endopeptidase activity(GO:0010950)
0.1 1.5 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 1.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.3 1.3 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 1.3 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 1.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 1.3 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.2 1.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 1.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 1.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.4 GO:0031105 septin complex(GO:0031105)
0.2 2.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 2.3 GO:0030904 retromer complex(GO:0030904)
0.1 2.2 GO:0071564 npBAF complex(GO:0071564)
0.2 2.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 2.1 GO:0031941 filamentous actin(GO:0031941)
0.5 1.9 GO:0008537 proteasome activator complex(GO:0008537)
0.1 1.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.6 GO:0030315 T-tubule(GO:0030315)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 1.4 GO:0031526 brush border membrane(GO:0031526)
0.1 1.3 GO:0045298 tubulin complex(GO:0045298)
0.1 1.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 1.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 1.0 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.9 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.8 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.8 GO:0008278 cohesin complex(GO:0008278)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 78 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.6 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.1 2.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.7 2.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 1.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 1.8 GO:0070697 activin receptor binding(GO:0070697)
0.2 1.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 1.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.5 GO:0017046 peptide hormone binding(GO:0017046)
0.0 1.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 1.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.4 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.1 1.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 1.3 GO:0050815 phosphoserine binding(GO:0050815)
0.2 1.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 1.3 GO:0005080 protein kinase C binding(GO:0005080)
0.2 1.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 1.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 1.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.3 1.0 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)