Motif ID: Egr1
Z-value: 1.239
Transcription factors associated with Egr1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Egr1 | ENSMUSG00000038418.7 | Egr1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Egr1 | mm10_v2_chr18_+_34861200_34861215 | 0.16 | 5.9e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.0 | GO:0032430 | positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466) |
0.5 | 1.9 | GO:2000313 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) |
0.4 | 1.2 | GO:1900039 | positive regulation of cellular response to hypoxia(GO:1900039) |
0.3 | 0.3 | GO:0071374 | cellular response to parathyroid hormone stimulus(GO:0071374) |
0.3 | 1.4 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
0.3 | 0.8 | GO:0002159 | desmosome assembly(GO:0002159) |
0.3 | 1.1 | GO:0010040 | response to iron(II) ion(GO:0010040) positive regulation of hydrogen peroxide metabolic process(GO:0010726) negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) cellular response to copper ion(GO:0071280) regulation of peroxidase activity(GO:2000468) |
0.2 | 1.2 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
0.2 | 2.2 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
0.2 | 0.6 | GO:0048211 | Golgi vesicle docking(GO:0048211) |
0.2 | 1.0 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) |
0.2 | 1.2 | GO:0019695 | choline metabolic process(GO:0019695) |
0.2 | 1.0 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
0.2 | 0.9 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.2 | 0.9 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
0.2 | 0.5 | GO:0033159 | negative regulation of protein import into nucleus, translocation(GO:0033159) protein poly-ADP-ribosylation(GO:0070212) |
0.2 | 0.5 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) |
0.2 | 0.7 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
0.2 | 0.5 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
0.2 | 0.7 | GO:0070305 | response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321) |
0.2 | 1.9 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.1 | 0.9 | GO:1900451 | positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969) |
0.1 | 0.4 | GO:0010512 | negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) |
0.1 | 0.6 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.1 | 0.7 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
0.1 | 0.4 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
0.1 | 0.4 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
0.1 | 0.8 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) positive regulation of B cell receptor signaling pathway(GO:0050861) |
0.1 | 0.4 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
0.1 | 0.5 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
0.1 | 1.1 | GO:0061368 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
0.1 | 0.9 | GO:0071732 | cellular response to nitric oxide(GO:0071732) |
0.1 | 2.4 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
0.1 | 0.8 | GO:0032796 | uropod organization(GO:0032796) |
0.1 | 0.6 | GO:2001025 | positive regulation of response to drug(GO:2001025) |
0.1 | 0.5 | GO:0021698 | cerebellar cortex structural organization(GO:0021698) |
0.1 | 0.8 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
0.1 | 1.0 | GO:1901660 | calcium ion export(GO:1901660) |
0.1 | 0.9 | GO:0060732 | positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
0.1 | 2.1 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
0.1 | 0.6 | GO:0060648 | mammary gland bud morphogenesis(GO:0060648) |
0.1 | 0.4 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.1 | 1.1 | GO:0043084 | penile erection(GO:0043084) |
0.1 | 0.5 | GO:0072368 | regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368) |
0.1 | 0.6 | GO:0033600 | negative regulation of mammary gland epithelial cell proliferation(GO:0033600) |
0.1 | 0.3 | GO:0045014 | ectoderm formation(GO:0001705) detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594) |
0.1 | 0.8 | GO:0097264 | self proteolysis(GO:0097264) |
0.1 | 0.6 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.1 | 0.4 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
0.1 | 0.4 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
0.1 | 0.3 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
0.1 | 2.2 | GO:0006491 | N-glycan processing(GO:0006491) |
0.1 | 0.4 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
0.1 | 0.5 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
0.1 | 1.3 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.1 | 0.2 | GO:0048296 | isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) |
0.1 | 0.2 | GO:1903334 | positive regulation of protein folding(GO:1903334) |
0.1 | 0.3 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
0.1 | 1.6 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
0.1 | 0.4 | GO:0032532 | regulation of microvillus length(GO:0032532) |
0.1 | 0.5 | GO:1900116 | sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
0.1 | 0.4 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
0.1 | 0.4 | GO:0070314 | G1 to G0 transition(GO:0070314) |
0.1 | 0.2 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
0.1 | 0.2 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
0.1 | 0.5 | GO:0097369 | sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.1 | 0.8 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
0.1 | 0.5 | GO:0015862 | uridine transport(GO:0015862) |
0.1 | 0.2 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
0.1 | 0.6 | GO:0060736 | prostate gland growth(GO:0060736) |
0.1 | 0.1 | GO:0002678 | positive regulation of chronic inflammatory response(GO:0002678) |
0.1 | 0.2 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
0.1 | 0.9 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
0.1 | 0.7 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
0.1 | 0.7 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
0.1 | 0.3 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
0.1 | 0.7 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
0.1 | 0.1 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
0.1 | 0.4 | GO:0001956 | positive regulation of neurotransmitter secretion(GO:0001956) |
0.1 | 0.1 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
0.1 | 0.5 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.1 | 0.2 | GO:1900673 | pons maturation(GO:0021586) olefin metabolic process(GO:1900673) |
0.1 | 0.5 | GO:0033008 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
0.1 | 0.6 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
0.1 | 0.2 | GO:0002447 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) |
0.0 | 0.2 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
0.0 | 0.4 | GO:0051639 | actin filament network formation(GO:0051639) |
0.0 | 0.1 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.0 | 0.8 | GO:1900273 | positive regulation of long-term synaptic potentiation(GO:1900273) |
0.0 | 0.2 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.0 | 0.6 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
0.0 | 0.3 | GO:0000050 | urea cycle(GO:0000050) urea metabolic process(GO:0019627) |
0.0 | 0.1 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
0.0 | 0.3 | GO:0034047 | regulation of protein phosphatase type 2A activity(GO:0034047) |
0.0 | 0.2 | GO:0051189 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
0.0 | 0.3 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.0 | 0.3 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
0.0 | 0.4 | GO:0055013 | cardiac muscle cell development(GO:0055013) |
0.0 | 0.6 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
0.0 | 0.1 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
0.0 | 0.2 | GO:1900016 | negative regulation of cytokine production involved in inflammatory response(GO:1900016) |
0.0 | 0.1 | GO:0071677 | positive regulation of mononuclear cell migration(GO:0071677) |
0.0 | 0.2 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
0.0 | 0.2 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216) |
0.0 | 0.2 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
0.0 | 0.1 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
0.0 | 0.4 | GO:0006706 | steroid catabolic process(GO:0006706) |
0.0 | 0.1 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
0.0 | 0.1 | GO:0042908 | xenobiotic transport(GO:0042908) |
0.0 | 0.1 | GO:0031509 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
0.0 | 0.6 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.0 | 0.1 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
0.0 | 0.2 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
0.0 | 0.8 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
0.0 | 1.0 | GO:0033014 | porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014) |
0.0 | 1.3 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
0.0 | 0.6 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
0.0 | 0.4 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.0 | 0.1 | GO:0030070 | insulin processing(GO:0030070) |
0.0 | 0.1 | GO:0046381 | CMP-N-acetylneuraminate metabolic process(GO:0046381) |
0.0 | 0.5 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
0.0 | 0.1 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
0.0 | 0.4 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 0.2 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
0.0 | 0.1 | GO:0006842 | tricarboxylic acid transport(GO:0006842) succinate transport(GO:0015744) citrate transport(GO:0015746) |
0.0 | 0.2 | GO:1904321 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
0.0 | 0.2 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
0.0 | 0.3 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.0 | 0.2 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
0.0 | 0.5 | GO:0006298 | mismatch repair(GO:0006298) |
0.0 | 0.2 | GO:0036120 | cellular response to platelet-derived growth factor stimulus(GO:0036120) |
0.0 | 0.2 | GO:0051770 | positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770) |
0.0 | 0.6 | GO:0031103 | axon regeneration(GO:0031103) |
0.0 | 0.5 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
0.0 | 0.1 | GO:0001923 | B-1 B cell differentiation(GO:0001923) |
0.0 | 0.1 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
0.0 | 0.1 | GO:0044243 | collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243) |
0.0 | 0.1 | GO:0060120 | auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120) |
0.0 | 0.6 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.0 | 0.2 | GO:0010640 | regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) |
0.0 | 0.5 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.0 | 0.6 | GO:0045921 | positive regulation of exocytosis(GO:0045921) |
0.0 | 0.2 | GO:0072520 | seminiferous tubule development(GO:0072520) |
0.0 | 0.2 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
0.0 | 0.0 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
0.0 | 0.3 | GO:0048671 | negative regulation of collateral sprouting(GO:0048671) |
0.0 | 0.0 | GO:0006106 | fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401) |
0.0 | 0.2 | GO:0010388 | protein deneddylation(GO:0000338) cullin deneddylation(GO:0010388) |
0.0 | 0.0 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
0.0 | 0.0 | GO:0034447 | very-low-density lipoprotein particle clearance(GO:0034447) |
0.0 | 0.4 | GO:0090022 | regulation of neutrophil chemotaxis(GO:0090022) |
0.0 | 0.1 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
0.0 | 0.1 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.0 | 0.4 | GO:0043171 | peptide catabolic process(GO:0043171) |
0.0 | 0.4 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
0.0 | 0.2 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
0.0 | 0.1 | GO:0009396 | folic acid-containing compound biosynthetic process(GO:0009396) |
0.0 | 0.0 | GO:0031133 | cellular magnesium ion homeostasis(GO:0010961) regulation of axon diameter(GO:0031133) |
0.0 | 0.1 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
0.0 | 0.4 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
0.0 | 0.1 | GO:0097501 | stress response to metal ion(GO:0097501) |
0.0 | 0.4 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
0.0 | 0.1 | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
0.0 | 0.4 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
0.0 | 0.0 | GO:0035553 | oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553) |
0.0 | 0.1 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
0.0 | 0.1 | GO:1904690 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
0.0 | 0.7 | GO:0007492 | endoderm development(GO:0007492) |
0.0 | 0.4 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.0 | 0.3 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
0.0 | 0.6 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
0.0 | 0.3 | GO:0006356 | regulation of transcription from RNA polymerase I promoter(GO:0006356) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.1 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.2 | 1.0 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.2 | 1.4 | GO:0008091 | spectrin(GO:0008091) |
0.2 | 1.3 | GO:0044294 | dendritic growth cone(GO:0044294) |
0.2 | 1.7 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
0.2 | 0.4 | GO:0016011 | dystroglycan complex(GO:0016011) |
0.2 | 2.1 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.1 | 0.4 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
0.1 | 0.3 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
0.1 | 0.6 | GO:0005955 | calcineurin complex(GO:0005955) |
0.1 | 0.4 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.1 | 1.2 | GO:0097449 | astrocyte projection(GO:0097449) |
0.1 | 0.3 | GO:0032127 | dense core granule membrane(GO:0032127) |
0.1 | 0.5 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.1 | 0.8 | GO:0070688 | MLL5-L complex(GO:0070688) |
0.1 | 0.8 | GO:0044327 | dendritic spine head(GO:0044327) |
0.1 | 0.5 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
0.1 | 2.3 | GO:0032590 | dendrite membrane(GO:0032590) |
0.1 | 2.1 | GO:0051233 | spindle midzone(GO:0051233) |
0.1 | 0.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.1 | 0.1 | GO:0044194 | cytolytic granule(GO:0044194) |
0.1 | 0.5 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.1 | 0.6 | GO:0005642 | annulate lamellae(GO:0005642) |
0.1 | 0.2 | GO:0090537 | CERF complex(GO:0090537) |
0.1 | 1.7 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.1 | 2.1 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.0 | 0.4 | GO:0042589 | zymogen granule membrane(GO:0042589) |
0.0 | 1.8 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.0 | 2.8 | GO:0034704 | calcium channel complex(GO:0034704) |
0.0 | 0.4 | GO:0016589 | NURF complex(GO:0016589) |
0.0 | 0.3 | GO:1990635 | proximal dendrite(GO:1990635) |
0.0 | 0.2 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
0.0 | 0.1 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
0.0 | 0.2 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.0 | 0.5 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.0 | 0.2 | GO:0031523 | Myb complex(GO:0031523) |
0.0 | 0.4 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.0 | 2.6 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.0 | 0.4 | GO:0061617 | MICOS complex(GO:0061617) |
0.0 | 0.9 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 0.5 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
0.0 | 2.3 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 0.2 | GO:0042825 | TAP complex(GO:0042825) |
0.0 | 0.7 | GO:0045120 | pronucleus(GO:0045120) |
0.0 | 0.4 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 0.2 | GO:0072687 | meiotic spindle(GO:0072687) |
0.0 | 0.1 | GO:1903095 | microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095) |
0.0 | 0.1 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.0 | 0.6 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 0.3 | GO:0031105 | septin complex(GO:0031105) |
0.0 | 0.5 | GO:0002102 | podosome(GO:0002102) |
0.0 | 1.1 | GO:0030667 | secretory granule membrane(GO:0030667) |
0.0 | 0.2 | GO:0070695 | FHF complex(GO:0070695) |
0.0 | 0.2 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
0.0 | 0.5 | GO:0005605 | basal lamina(GO:0005605) |
0.0 | 0.2 | GO:0045298 | tubulin complex(GO:0045298) |
0.0 | 0.6 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 0.2 | GO:0030125 | clathrin vesicle coat(GO:0030125) |
0.0 | 0.1 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.0 | 0.1 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
0.0 | 1.2 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.9 | GO:0031201 | SNARE complex(GO:0031201) |
0.0 | 0.5 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 0.2 | GO:0001673 | male germ cell nucleus(GO:0001673) |
0.0 | 0.1 | GO:0001740 | Barr body(GO:0001740) |
0.0 | 0.7 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 0.1 | GO:0089701 | U2AF(GO:0089701) |
0.0 | 0.8 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 0.2 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.0 | 0.5 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 0.2 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.4 | GO:0032420 | stereocilium(GO:0032420) |
0.0 | 0.3 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 1.3 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.2 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 0.2 | GO:0000145 | exocyst(GO:0000145) |
0.0 | 0.4 | GO:0005902 | microvillus(GO:0005902) |
0.0 | 0.2 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.0 | 0.6 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
0.0 | 1.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.0 | 0.2 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.2 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
0.3 | 2.3 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
0.3 | 1.5 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.2 | 2.7 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
0.2 | 1.6 | GO:0035184 | histone threonine kinase activity(GO:0035184) |
0.2 | 1.4 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
0.2 | 1.1 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.2 | 0.7 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
0.2 | 1.1 | GO:0050544 | arachidonic acid binding(GO:0050544) |
0.2 | 2.0 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
0.2 | 1.8 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
0.2 | 1.7 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
0.1 | 0.4 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
0.1 | 0.7 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
0.1 | 0.5 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
0.1 | 0.4 | GO:0070012 | oligopeptidase activity(GO:0070012) |
0.1 | 2.0 | GO:0043274 | phospholipase binding(GO:0043274) |
0.1 | 0.5 | GO:0033192 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192) |
0.1 | 0.4 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.1 | 1.0 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.1 | 0.2 | GO:0070615 | nucleosome-dependent ATPase activity(GO:0070615) |
0.1 | 0.2 | GO:0019153 | protein-disulfide reductase (glutathione) activity(GO:0019153) |
0.1 | 0.8 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.1 | 0.5 | GO:0036122 | BMP binding(GO:0036122) |
0.1 | 0.8 | GO:0030957 | Tat protein binding(GO:0030957) |
0.1 | 0.3 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
0.1 | 0.5 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.1 | 0.2 | GO:0070052 | collagen V binding(GO:0070052) |
0.1 | 0.2 | GO:0032896 | palmitoyl-CoA 9-desaturase activity(GO:0032896) |
0.1 | 0.2 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
0.1 | 0.2 | GO:0001847 | opsonin receptor activity(GO:0001847) |
0.1 | 0.5 | GO:0005451 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
0.1 | 1.4 | GO:0030506 | ankyrin binding(GO:0030506) |
0.1 | 0.5 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
0.1 | 1.4 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 2.3 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
0.1 | 1.2 | GO:0032183 | SUMO binding(GO:0032183) |
0.1 | 1.1 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.1 | 0.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.1 | 0.7 | GO:0017166 | vinculin binding(GO:0017166) |
0.0 | 0.2 | GO:0050815 | phosphoserine binding(GO:0050815) |
0.0 | 0.1 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
0.0 | 0.8 | GO:0050253 | prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) retinyl-palmitate esterase activity(GO:0050253) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032) |
0.0 | 0.6 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
0.0 | 0.1 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
0.0 | 0.4 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.0 | 1.4 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
0.0 | 0.3 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
0.0 | 0.4 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.0 | 0.1 | GO:0003977 | UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977) |
0.0 | 0.2 | GO:0005025 | transforming growth factor beta-activated receptor activity(GO:0005024) transforming growth factor beta receptor activity, type I(GO:0005025) |
0.0 | 0.5 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
0.0 | 0.2 | GO:0034916 | 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760) |
0.0 | 0.5 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
0.0 | 0.5 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
0.0 | 1.5 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 1.1 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.1 | GO:0018121 | imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102) |
0.0 | 0.6 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.0 | 0.2 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
0.0 | 0.3 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.0 | 0.4 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.0 | 0.1 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
0.0 | 0.9 | GO:0017046 | peptide hormone binding(GO:0017046) |
0.0 | 0.1 | GO:0097001 | ceramide binding(GO:0097001) |
0.0 | 0.5 | GO:0015215 | nucleotide transmembrane transporter activity(GO:0015215) |
0.0 | 0.1 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
0.0 | 0.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.0 | 0.2 | GO:1990715 | mRNA CDS binding(GO:1990715) |
0.0 | 0.0 | GO:0031762 | alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762) |
0.0 | 0.5 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 1.1 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
0.0 | 0.1 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
0.0 | 0.4 | GO:0030553 | cGMP binding(GO:0030553) |
0.0 | 0.9 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.5 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.0 | 0.6 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.0 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) |
0.0 | 0.2 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.0 | 0.4 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.1 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056) |
0.0 | 0.1 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.0 | 0.3 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.0 | 0.9 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 0.2 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.0 | 0.2 | GO:0022843 | voltage-gated cation channel activity(GO:0022843) |
0.0 | 0.5 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
0.0 | 0.4 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.0 | 0.4 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.4 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 1.2 | GO:0019955 | cytokine binding(GO:0019955) |
0.0 | 0.3 | GO:0003988 | acetyl-CoA C-acyltransferase activity(GO:0003988) |
0.0 | 0.4 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 0.2 | GO:0001223 | transcription coactivator binding(GO:0001223) |
0.0 | 0.7 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 0.5 | GO:0004532 | 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896) |
0.0 | 0.0 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
0.0 | 0.1 | GO:0051393 | alpha-actinin binding(GO:0051393) |
0.0 | 0.2 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.0 | 0.3 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.0 | 0.1 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
0.0 | 0.3 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.2 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
0.0 | 0.5 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.8 | GO:0050839 | cell adhesion molecule binding(GO:0050839) |
0.0 | 0.5 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 0.1 | GO:0070403 | NAD+ binding(GO:0070403) |
0.0 | 0.0 | GO:0032422 | translation repressor activity, nucleic acid binding(GO:0000900) purine-rich negative regulatory element binding(GO:0032422) |
0.0 | 0.7 | GO:0003684 | damaged DNA binding(GO:0003684) |
0.0 | 0.0 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
0.0 | 0.1 | GO:0050733 | RS domain binding(GO:0050733) |
0.0 | 1.1 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.8 | GO:0051087 | chaperone binding(GO:0051087) |
0.0 | 0.2 | GO:0030552 | cAMP binding(GO:0030552) |
0.0 | 1.1 | GO:0044325 | ion channel binding(GO:0044325) |
0.0 | 0.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |