Motif ID: En2

Z-value: 0.810


Transcription factors associated with En2:

Gene SymbolEntrez IDGene Name
En2 ENSMUSG00000039095.7 En2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
En2mm10_v2_chr5_+_28165690_281657170.126.8e-01Click!


Activity profile for motif En2.

activity profile for motif En2


Sorted Z-values histogram for motif En2

Sorted Z-values for motif En2



Network of associatons between targets according to the STRING database.



First level regulatory network of En2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 173 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_116067213 2.336 ENSMUST00000152412.1
 G630016G05Rik
RIKEN cDNA G630016G05 gene
chrM_+_7005 1.803 ENSMUST00000082405.1
 mt-Co2
mitochondrially encoded cytochrome c oxidase II
chrM_+_7759 1.654 ENSMUST00000082407.1
ENSMUST00000082408.1
 mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr5_-_62766153 1.628 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr13_-_47106176 1.621 ENSMUST00000021807.6
ENSMUST00000135278.1
 Dek

DEK oncogene (DNA binding)

chrM_+_3906 1.563 ENSMUST00000082396.1
 mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr6_+_125552948 1.449 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chr14_-_55560340 1.449 ENSMUST00000066106.3
 A730061H03Rik
RIKEN cDNA A730061H03 gene
chr1_+_104768510 1.400 ENSMUST00000062528.8
 Cdh20
cadherin 20
chrM_+_10167 1.394 ENSMUST00000082414.1
 mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr18_-_80986578 1.299 ENSMUST00000057950.7
 Sall3
sal-like 3 (Drosophila)
chrM_+_11734 1.208 ENSMUST00000082418.1
 mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr11_-_102946688 1.207 ENSMUST00000057849.5
 C1ql1
complement component 1, q subcomponent-like 1
chr4_+_21848039 1.176 ENSMUST00000098238.2
ENSMUST00000108229.1
 Sfrs18

serine/arginine-rich splicing factor 18

chr13_-_23710714 1.171 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
 Hfe


hemochromatosis


chr14_-_67715585 1.160 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
 Cdca2


cell division cycle associated 2


chrX_+_56454871 1.098 ENSMUST00000039374.2
ENSMUST00000101553.2
 Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr2_-_116067391 1.074 ENSMUST00000140185.1
 2700033N17Rik
RIKEN cDNA 2700033N17 gene
chrX_+_136741821 1.062 ENSMUST00000089350.4
 BC065397
cDNA sequence BC065397
chr2_+_25372315 1.055 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
 Sapcd2


suppressor APC domain containing 2



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 2.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.8 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 1.8 GO:0001889 liver development(GO:0001889)
0.3 1.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 1.7 GO:0022900 electron transport chain(GO:0022900)
0.1 1.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4 1.6 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 1.4 GO:0030953 astral microtubule organization(GO:0030953)
0.1 1.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.4 1.2 GO:0061743 motor learning(GO:0061743)
0.4 1.2 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.0 1.1 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.2 1.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.0 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 0.9 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.9 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.9 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.9 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.9 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.0 GO:0070469 respiratory chain(GO:0070469)
0.1 1.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 1.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 1.2 GO:0044301 climbing fiber(GO:0044301)
0.2 1.2 GO:1990357 terminal web(GO:1990357)
0.1 1.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 0.9 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.9 GO:0000124 SAGA complex(GO:0000124)
0.2 0.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.7 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.1 0.5 GO:0071438 NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0051286 cell tip(GO:0051286)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 2.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 2.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 1.7 GO:0008483 transaminase activity(GO:0008483)
0.0 1.7 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.2 1.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 1.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 0.9 GO:0004104 choline kinase activity(GO:0004103) cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.0 0.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.2 0.7 GO:0036004 GAF domain binding(GO:0036004)
0.0 0.7 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 0.6 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 0.5 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.5 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)