Motif ID: Ep300
Z-value: 0.664
Transcription factors associated with Ep300:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Ep300 | ENSMUSG00000055024.6 | Ep300 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Ep300 | mm10_v2_chr15_+_81586206_81586250 | 0.70 | 4.9e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.4 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
0.4 | 1.7 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
0.4 | 1.7 | GO:0051866 | general adaptation syndrome(GO:0051866) |
0.3 | 1.1 | GO:0032289 | central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912) |
0.3 | 2.9 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.2 | 0.9 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.2 | 0.5 | GO:0070889 | platelet alpha granule organization(GO:0070889) |
0.2 | 1.1 | GO:0001842 | neural fold formation(GO:0001842) |
0.2 | 0.6 | GO:0035795 | negative regulation of mitochondrial membrane permeability(GO:0035795) |
0.1 | 0.4 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
0.1 | 1.2 | GO:0051639 | actin filament network formation(GO:0051639) |
0.1 | 0.4 | GO:0034145 | positive regulation of toll-like receptor 4 signaling pathway(GO:0034145) |
0.1 | 0.3 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
0.1 | 0.7 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
0.1 | 1.4 | GO:0014049 | positive regulation of glutamate secretion(GO:0014049) |
0.1 | 0.7 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
0.1 | 1.0 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
0.1 | 0.4 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
0.1 | 0.4 | GO:0090234 | cellular response to testosterone stimulus(GO:0071394) regulation of kinetochore assembly(GO:0090234) |
0.1 | 0.5 | GO:0089711 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) L-glutamate transmembrane transport(GO:0089711) |
0.1 | 0.8 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.1 | 0.3 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
0.1 | 0.3 | GO:0071105 | response to interleukin-11(GO:0071105) osteoclast fusion(GO:0072675) |
0.1 | 0.2 | GO:0046898 | response to cycloheximide(GO:0046898) |
0.1 | 0.4 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
0.1 | 0.6 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.1 | 0.4 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
0.1 | 0.4 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
0.1 | 0.3 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
0.0 | 0.3 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
0.0 | 0.1 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) |
0.0 | 0.6 | GO:0035635 | entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535) |
0.0 | 0.3 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.0 | 0.4 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
0.0 | 0.2 | GO:0070829 | heterochromatin maintenance(GO:0070829) |
0.0 | 0.1 | GO:0015960 | diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) |
0.0 | 0.2 | GO:0090273 | regulation of somatostatin secretion(GO:0090273) |
0.0 | 0.6 | GO:0048680 | positive regulation of axon regeneration(GO:0048680) |
0.0 | 0.3 | GO:0048149 | adult feeding behavior(GO:0008343) behavioral response to ethanol(GO:0048149) |
0.0 | 0.2 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
0.0 | 0.3 | GO:0042268 | regulation of cytolysis(GO:0042268) |
0.0 | 0.1 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
0.0 | 0.3 | GO:0035372 | protein localization to microtubule(GO:0035372) |
0.0 | 0.1 | GO:1901250 | regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250) |
0.0 | 0.1 | GO:0039530 | MDA-5 signaling pathway(GO:0039530) |
0.0 | 0.7 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
0.0 | 0.1 | GO:0060279 | positive regulation of ovulation(GO:0060279) |
0.0 | 0.3 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.0 | 0.7 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
0.0 | 0.9 | GO:0050982 | detection of mechanical stimulus(GO:0050982) |
0.0 | 1.0 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) motor neuron axon guidance(GO:0008045) |
0.0 | 0.3 | GO:0060510 | Type II pneumocyte differentiation(GO:0060510) |
0.0 | 0.3 | GO:0071371 | cellular response to electrical stimulus(GO:0071257) cellular response to gonadotropin stimulus(GO:0071371) |
0.0 | 0.6 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
0.0 | 0.4 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) negative regulation of cell projection organization(GO:0031345) |
0.0 | 0.1 | GO:0072015 | glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310) |
0.0 | 0.1 | GO:0032472 | Golgi calcium ion transport(GO:0032472) |
0.0 | 0.3 | GO:0007020 | microtubule nucleation(GO:0007020) |
0.0 | 0.2 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
0.0 | 0.2 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
0.0 | 0.1 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
0.0 | 0.1 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
0.0 | 0.2 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.0 | 0.5 | GO:0000002 | mitochondrial genome maintenance(GO:0000002) |
0.0 | 0.6 | GO:0019319 | hexose biosynthetic process(GO:0019319) |
0.0 | 0.1 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.0 | 0.3 | GO:0006379 | mRNA cleavage(GO:0006379) |
0.0 | 0.2 | GO:0032225 | regulation of synaptic transmission, dopaminergic(GO:0032225) regulation of grooming behavior(GO:2000821) |
0.0 | 0.2 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.0 | 0.6 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.2 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
0.0 | 0.2 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
0.0 | 0.2 | GO:0044243 | collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.2 | GO:0032127 | dense core granule membrane(GO:0032127) |
0.1 | 1.3 | GO:0043083 | synaptic cleft(GO:0043083) |
0.1 | 0.3 | GO:0005816 | spindle pole body(GO:0005816) |
0.1 | 3.0 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.1 | 0.3 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.1 | 0.8 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.1 | 1.0 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.1 | 0.3 | GO:1990130 | Iml1 complex(GO:1990130) |
0.1 | 0.9 | GO:0097539 | ciliary transition fiber(GO:0097539) |
0.1 | 0.3 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
0.1 | 0.6 | GO:0032584 | growth cone membrane(GO:0032584) |
0.1 | 0.3 | GO:0072487 | MSL complex(GO:0072487) |
0.0 | 0.3 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
0.0 | 0.7 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 0.1 | GO:0005899 | insulin receptor complex(GO:0005899) |
0.0 | 0.6 | GO:0097470 | ribbon synapse(GO:0097470) |
0.0 | 0.2 | GO:0070876 | SOSS complex(GO:0070876) |
0.0 | 0.2 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.0 | 1.4 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.0 | 0.7 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.6 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 1.8 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.3 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
0.0 | 0.1 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.0 | 0.3 | GO:0005675 | holo TFIIH complex(GO:0005675) |
0.0 | 0.2 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
0.0 | 0.4 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 0.4 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 0.1 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
0.0 | 0.1 | GO:0071817 | MMXD complex(GO:0071817) |
0.0 | 0.2 | GO:0005905 | clathrin-coated pit(GO:0005905) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.4 | GO:0031752 | D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752) |
0.6 | 2.9 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
0.3 | 0.8 | GO:0033883 | pyridoxal phosphatase activity(GO:0033883) |
0.2 | 0.6 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
0.2 | 0.6 | GO:0008521 | acetyl-CoA transporter activity(GO:0008521) |
0.2 | 1.3 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
0.1 | 0.6 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
0.1 | 0.4 | GO:0005118 | sevenless binding(GO:0005118) |
0.1 | 0.5 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.1 | 0.7 | GO:0046790 | virion binding(GO:0046790) |
0.1 | 1.4 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
0.1 | 0.3 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.1 | 0.3 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
0.1 | 1.2 | GO:0017166 | vinculin binding(GO:0017166) |
0.1 | 0.4 | GO:0033142 | progesterone receptor binding(GO:0033142) |
0.1 | 0.3 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
0.1 | 1.8 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 0.7 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
0.1 | 0.2 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
0.1 | 0.1 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.1 | 1.7 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.3 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
0.0 | 0.3 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) |
0.0 | 0.1 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.0 | 0.3 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
0.0 | 0.4 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
0.0 | 0.3 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
0.0 | 0.6 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.0 | 0.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.0 | 0.2 | GO:0016668 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668) |
0.0 | 0.2 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.0 | 0.4 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 0.7 | GO:0017025 | TBP-class protein binding(GO:0017025) |
0.0 | 1.0 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.0 | 0.9 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 1.7 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.4 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 0.4 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.1 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.0 | 0.1 | GO:0051718 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718) |
0.0 | 0.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.7 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.3 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.0 | 0.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 0.1 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.0 | 0.7 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 0.3 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.0 | 0.3 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.0 | 0.6 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
0.0 | 0.1 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
0.0 | 0.2 | GO:0005326 | neurotransmitter transporter activity(GO:0005326) |
0.0 | 0.1 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.0 | 0.1 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
0.0 | 0.2 | GO:0016805 | dipeptidase activity(GO:0016805) |