Motif ID: Epas1_Bcl3

Z-value: 1.306

Transcription factors associated with Epas1_Bcl3:

Gene SymbolEntrez IDGene Name
Bcl3 ENSMUSG00000053175.10 Bcl3
Epas1 ENSMUSG00000024140.9 Epas1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Epas1mm10_v2_chr17_+_86753900_86753914-0.019.7e-01Click!


Activity profile for motif Epas1_Bcl3.

activity profile for motif Epas1_Bcl3


Sorted Z-values histogram for motif Epas1_Bcl3

Sorted Z-values for motif Epas1_Bcl3



Network of associatons between targets according to the STRING database.



First level regulatory network of Epas1_Bcl3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_65671590 3.637 ENSMUST00000054351.4
 Ndnf
neuron-derived neurotrophic factor
chr2_+_169632996 3.237 ENSMUST00000109159.2
 Tshz2
teashirt zinc finger family member 2
chr8_-_48555846 2.543 ENSMUST00000110345.1
ENSMUST00000110343.1
 Tenm3

teneurin transmembrane protein 3

chr9_+_112227443 1.771 ENSMUST00000161216.1
 2310075C17Rik
RIKEN cDNA 2310075C17 gene
chr13_-_92131494 1.560 ENSMUST00000099326.3
ENSMUST00000146492.1
 Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr2_-_113217051 1.439 ENSMUST00000080673.5
 Ryr3
ryanodine receptor 3
chr6_+_15185203 1.378 ENSMUST00000154448.1
 Foxp2
forkhead box P2
chr3_-_132950043 1.285 ENSMUST00000117164.1
ENSMUST00000093971.4
ENSMUST00000042729.9
ENSMUST00000042744.9
ENSMUST00000117811.1
 Npnt




nephronectin




chr5_-_67847400 1.269 ENSMUST00000113652.1
ENSMUST00000113651.1
ENSMUST00000037380.8
 Atp8a1


ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1


chr4_+_123183456 1.256 ENSMUST00000126995.1
 Hpcal4
hippocalcin-like 4
chr14_-_60177482 1.198 ENSMUST00000140924.1
 Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr3_-_127225847 1.116 ENSMUST00000182726.1
ENSMUST00000182779.1
 Ank2

ankyrin 2, brain

chr8_+_82863351 1.045 ENSMUST00000078525.5
 Rnf150
ring finger protein 150
chr11_+_96251100 1.026 ENSMUST00000129907.2
 Gm53
predicted gene 53
chr3_+_134236483 0.959 ENSMUST00000181904.1
ENSMUST00000053048.9
 Cxxc4

CXXC finger 4

chr6_-_112947246 0.906 ENSMUST00000088373.4
 Srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr1_-_174921813 0.895 ENSMUST00000055294.3
 Grem2
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chrX_+_140664908 0.796 ENSMUST00000112990.1
ENSMUST00000112988.1
 Mid2

midline 2

chr5_+_130448801 0.794 ENSMUST00000111288.2
 Caln1
calneuron 1
chr5_-_30461902 0.788 ENSMUST00000133509.1
ENSMUST00000074171.6
ENSMUST00000114747.2
ENSMUST00000144125.1
 Otof



otoferlin




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 113 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.3 GO:0061042 vascular wound healing(GO:0061042)
0.4 3.0 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.3 2.6 GO:0097264 self proteolysis(GO:0097264)
0.2 1.7 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 1.4 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.2 1.3 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.1 1.3 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 1.0 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 1.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 1.0 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.9 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.9 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.7 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.2 0.6 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.6 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.3 GO:0005802 trans-Golgi network(GO:0005802)
0.1 1.7 GO:0031430 M band(GO:0031430)
0.3 1.4 GO:0030314 junctional membrane complex(GO:0030314)
0.3 1.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.0 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.8 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 0.7 GO:0043512 inhibin A complex(GO:0043512)
0.1 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.6 GO:0071953 elastic fiber(GO:0071953)
0.1 0.6 GO:0008091 spectrin(GO:0008091)
0.1 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.5 GO:0016600 flotillin complex(GO:0016600)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 3.0 GO:0008201 heparin binding(GO:0008201)
0.0 2.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 1.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.5 1.4 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 1.3 GO:0005178 integrin binding(GO:0005178)
0.1 1.0 GO:0030553 cGMP binding(GO:0030553)
0.0 1.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.9 GO:0036122 BMP binding(GO:0036122)
0.1 0.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 0.8 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 0.6 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639)