Motif ID: Erg

Z-value: 1.050


Transcription factors associated with Erg:

Gene SymbolEntrez IDGene Name
Erg ENSMUSG00000040732.12 Erg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ergmm10_v2_chr16_-_95459245_954593840.583.0e-02Click!


Activity profile for motif Erg.

activity profile for motif Erg


Sorted Z-values histogram for motif Erg

Sorted Z-values for motif Erg



Network of associatons between targets according to the STRING database.



First level regulatory network of Erg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_111733924 3.937 ENSMUST00000180627.1
 Gm26897
predicted gene, 26897
chr4_+_144892813 2.842 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr13_-_37050237 2.707 ENSMUST00000164727.1
 F13a1
coagulation factor XIII, A1 subunit
chr7_+_30413744 2.603 ENSMUST00000032800.9
 Tyrobp
TYRO protein tyrosine kinase binding protein
chr12_-_34528844 2.346 ENSMUST00000110819.2
 Hdac9
histone deacetylase 9
chr4_+_144893077 2.226 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr2_+_32646586 2.166 ENSMUST00000009705.7
ENSMUST00000167841.1
 Eng

endoglin

chr3_+_95526777 2.159 ENSMUST00000015667.2
ENSMUST00000116304.2
 Ctss

cathepsin S

chr16_+_36934976 2.138 ENSMUST00000023531.8
 Hcls1
hematopoietic cell specific Lyn substrate 1
chr11_-_101785252 2.095 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
 Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr12_+_75308308 1.998 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
 Rhoj


ras homolog gene family, member J


chr10_-_83648713 1.960 ENSMUST00000020500.7
 Appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr4_+_144893127 1.883 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr14_-_31168587 1.854 ENSMUST00000036618.7
 Stab1
stabilin 1
chr5_+_75152274 1.795 ENSMUST00000000476.8
 Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr11_-_69695802 1.770 ENSMUST00000108649.1
ENSMUST00000174159.1
ENSMUST00000181810.1
 BC096441

Tnfsf12
cDNA sequence BC096441

tumor necrosis factor (ligand) superfamily, member 12
chr11_-_48816936 1.695 ENSMUST00000140800.1
 Trim41
tripartite motif-containing 41
chr6_-_72390659 1.679 ENSMUST00000059983.9
 Vamp8
vesicle-associated membrane protein 8
chr9_-_54661870 1.596 ENSMUST00000034822.5
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr9_+_21526144 1.554 ENSMUST00000086361.5
ENSMUST00000179459.1
ENSMUST00000173769.2
 AB124611


cDNA sequence AB124611



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 160 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 7.0 GO:0042572 retinol metabolic process(GO:0042572)
0.0 3.8 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 3.2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.6 3.1 GO:2001204 regulation of osteoclast development(GO:2001204)
0.2 2.7 GO:0030574 collagen catabolic process(GO:0030574)
0.2 2.7 GO:0018149 peptide cross-linking(GO:0018149)
0.1 2.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 2.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.7 2.2 GO:0003032 detection of oxygen(GO:0003032)
0.4 2.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2 2.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.3 2.0 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.2 2.0 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 2.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.6 1.8 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.6 1.7 GO:0090187 zymogen granule exocytosis(GO:0070625) positive regulation of pancreatic juice secretion(GO:0090187)
0.2 1.5 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.2 1.5 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.4 1.4 GO:1900272 negative regulation of long-term synaptic potentiation(GO:1900272)
0.2 1.4 GO:0048752 semicircular canal morphogenesis(GO:0048752)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.2 GO:0072562 blood microparticle(GO:0072562)
0.0 4.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 3.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 2.6 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.6 2.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 2.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 1.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.6 GO:0005902 microvillus(GO:0005902)
0.1 1.4 GO:0001739 sex chromatin(GO:0001739)
0.0 1.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.4 1.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.0 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.9 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 0.8 GO:0036488 CHOP-C/EBP complex(GO:0036488)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 7.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 4.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 3.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 3.5 GO:0070888 E-box binding(GO:0070888)
0.0 3.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 3.1 GO:0017124 SH3 domain binding(GO:0017124)
0.7 2.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 2.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 2.6 GO:0001968 fibronectin binding(GO:0001968)
0.5 2.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 2.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.7 2.2 GO:0005534 galactose binding(GO:0005534)
0.1 2.1 GO:0017091 AU-rich element binding(GO:0017091)
0.2 1.9 GO:0017081 chloride channel regulator activity(GO:0017081)
0.2 1.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 1.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 1.5 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 1.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.4 1.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.2 1.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)