Motif ID: Esrrg

Z-value: 0.586


Transcription factors associated with Esrrg:

Gene SymbolEntrez IDGene Name
Esrrg ENSMUSG00000026610.7 Esrrg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Esrrgmm10_v2_chr1_+_187997821_187997834-0.544.7e-02Click!


Activity profile for motif Esrrg.

activity profile for motif Esrrg


Sorted Z-values histogram for motif Esrrg

Sorted Z-values for motif Esrrg



Network of associatons between targets according to the STRING database.



First level regulatory network of Esrrg

PNG image of the network

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Top targets:


Showing 1 to 20 of 146 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_68869563 2.934 ENSMUST00000054551.2
 1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr1_+_104768510 2.202 ENSMUST00000062528.8
 Cdh20
cadherin 20
chr10_+_79716588 1.793 ENSMUST00000099513.1
ENSMUST00000020581.2
 Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr8_-_46294592 1.420 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr7_-_93081027 1.240 ENSMUST00000098303.1
 Gm9934
predicted gene 9934
chr14_+_20929416 1.167 ENSMUST00000022369.7
 Vcl
vinculin
chr19_+_6399746 1.101 ENSMUST00000113468.1
 Rasgrp2
RAS, guanyl releasing protein 2
chr19_+_6400523 1.074 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
 Rasgrp2



RAS, guanyl releasing protein 2



chr9_-_107668967 1.072 ENSMUST00000177567.1
 Slc38a3
solute carrier family 38, member 3
chr5_+_63649335 1.061 ENSMUST00000159584.1
 3110047P20Rik
RIKEN cDNA 3110047P20 gene
chr15_-_79285502 1.058 ENSMUST00000165408.1
 Baiap2l2
BAI1-associated protein 2-like 2
chr19_+_6400611 0.959 ENSMUST00000113467.1
 Rasgrp2
RAS, guanyl releasing protein 2
chr4_-_128962420 0.915 ENSMUST00000119354.1
ENSMUST00000106068.1
ENSMUST00000030581.3
 Adc


arginine decarboxylase


chr19_+_53529100 0.837 ENSMUST00000038287.6
 Dusp5
dual specificity phosphatase 5
chr5_-_137613759 0.828 ENSMUST00000155251.1
ENSMUST00000124693.1
 Pcolce

procollagen C-endopeptidase enhancer protein

chr1_+_75546522 0.826 ENSMUST00000138814.1
 Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr3_-_90514250 0.785 ENSMUST00000107340.1
ENSMUST00000060738.8
 S100a1

S100 calcium binding protein A1

chr19_-_43674844 0.690 ENSMUST00000046038.7
 Slc25a28
solute carrier family 25, member 28
chr15_-_42676967 0.682 ENSMUST00000022921.5
 Angpt1
angiopoietin 1
chr3_+_90514435 0.660 ENSMUST00000048138.6
ENSMUST00000181271.1
 S100a13

S100 calcium binding protein A13


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 2.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.4 1.8 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.1 1.5 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 1.4 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.0 1.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.3 1.1 GO:0006867 asparagine transport(GO:0006867) glutamine transport(GO:0006868)
0.1 1.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 1.0 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.1 0.8 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.8 GO:0001706 endoderm formation(GO:0001706)
0.2 0.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 0.7 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.7 GO:0009409 response to cold(GO:0009409)
0.2 0.6 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0 0.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.5 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
0.1 0.5 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 GO:0032590 dendrite membrane(GO:0032590)
0.1 1.1 GO:0071439 clathrin complex(GO:0071439)
0.1 1.0 GO:0046930 pore complex(GO:0046930)
0.1 0.8 GO:0005916 fascia adherens(GO:0005916)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.2 0.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 0.5 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.1 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.2 GO:0098803 respiratory chain complex(GO:0098803)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 2.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.4 1.8 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 1.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 1.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 1.1 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.8 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.8 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.7 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.7 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 0.5 GO:0030172 troponin C binding(GO:0030172)
0.1 0.5 GO:0019841 retinol binding(GO:0019841)
0.1 0.5 GO:0015288 porin activity(GO:0015288)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)