Motif ID: Ets1

Z-value: 0.766


Transcription factors associated with Ets1:

Gene SymbolEntrez IDGene Name
Ets1 ENSMUSG00000032035.9 Ets1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ets1mm10_v2_chr9_+_32696005_32696121-0.126.9e-01Click!


Activity profile for motif Ets1.

activity profile for motif Ets1


Sorted Z-values histogram for motif Ets1

Sorted Z-values for motif Ets1



Network of associatons between targets according to the STRING database.



First level regulatory network of Ets1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_+_1010543 1.668 ENSMUST00000091197.3
Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr6_+_5725639 1.557 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr6_+_5725812 1.323 ENSMUST00000115554.1
ENSMUST00000153942.1
Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chr7_+_100495987 1.006 ENSMUST00000133044.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr15_-_66812593 0.944 ENSMUST00000100572.3
Sla
src-like adaptor
chr15_-_66969616 0.915 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
Ndrg1



N-myc downstream regulated gene 1



chr14_-_30626196 0.876 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
Prkcd


protein kinase C, delta


chr5_-_44799643 0.863 ENSMUST00000070748.5
Ldb2
LIM domain binding 2
chr7_+_119793987 0.859 ENSMUST00000033218.8
ENSMUST00000106520.1
2610020H08Rik

RIKEN cDNA 2610020H08 gene

chr15_-_12592556 0.797 ENSMUST00000075317.5
Pdzd2
PDZ domain containing 2
chr7_-_127876777 0.784 ENSMUST00000106262.1
ENSMUST00000106263.1
ENSMUST00000054415.5
Zfp668


zinc finger protein 668


chr11_-_20112876 0.762 ENSMUST00000000137.7
Actr2
ARP2 actin-related protein 2
chr11_-_84880195 0.743 ENSMUST00000067058.2
ENSMUST00000108080.2
Pigw

phosphatidylinositol glycan anchor biosynthesis, class W

chr2_-_57113053 0.742 ENSMUST00000112627.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr4_+_103313806 0.735 ENSMUST00000035780.3
Oma1
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr6_-_99096196 0.691 ENSMUST00000175886.1
Foxp1
forkhead box P1
chr8_-_9977650 0.689 ENSMUST00000170033.1
Lig4
ligase IV, DNA, ATP-dependent
chr6_-_136173492 0.682 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr3_+_98382538 0.672 ENSMUST00000178372.1
Zfp697
zinc finger protein 697
chr13_-_29984219 0.658 ENSMUST00000146092.1
E2f3
E2F transcription factor 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 296 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.5 1.5 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.2 1.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 1.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.3 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 1.3 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.3 1.2 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 1.2 GO:0006415 translational termination(GO:0006415)
0.1 1.0 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 1.0 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.2 0.9 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.1 0.9 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.3 0.8 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.2 0.8 GO:0051311 meiotic metaphase plate congression(GO:0051311)
0.0 0.8 GO:0010225 response to UV-C(GO:0010225)
0.0 0.8 GO:0010669 epithelial structure maintenance(GO:0010669)
0.2 0.7 GO:0019085 early viral transcription(GO:0019085)
0.2 0.7 GO:0051866 general adaptation syndrome(GO:0051866)
0.2 0.7 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.7 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 140 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.0 GO:0031430 M band(GO:0031430)
0.3 1.3 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 1.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 0.8 GO:0008623 CHRAC(GO:0008623)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.6 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.6 GO:0071439 clathrin complex(GO:0071439)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.5 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 183 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 2.9 GO:0045503 dynein light chain binding(GO:0045503)
0.1 2.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 2.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 1.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.5 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 1.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.4 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.0 1.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.3 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.3 1.2 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 1.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 0.9 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.0 0.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.9 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 0.8 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)