Motif ID: Ets2

Z-value: 0.552


Transcription factors associated with Ets2:

Gene SymbolEntrez IDGene Name
Ets2 ENSMUSG00000022895.8 Ets2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ets2mm10_v2_chr16_+_95702044_95702094-0.019.6e-01Click!


Activity profile for motif Ets2.

activity profile for motif Ets2


Sorted Z-values histogram for motif Ets2

Sorted Z-values for motif Ets2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ets2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_29984219 0.675 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr1_+_185454803 0.624 ENSMUST00000061093.6
 Slc30a10
solute carrier family 30, member 10
chr11_-_20112876 0.528 ENSMUST00000000137.7
 Actr2
ARP2 actin-related protein 2
chrX_+_157818435 0.523 ENSMUST00000087157.4
 Klhl34
kelch-like 34
chr10_-_6980376 0.512 ENSMUST00000105617.1
 Ipcef1
interaction protein for cytohesin exchange factors 1
chr4_+_103313806 0.489 ENSMUST00000035780.3
 Oma1
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr7_+_100495987 0.486 ENSMUST00000133044.1
 Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr7_+_75701965 0.467 ENSMUST00000094307.3
 Akap13
A kinase (PRKA) anchor protein 13
chr11_-_109722214 0.454 ENSMUST00000020938.7
 Fam20a
family with sequence similarity 20, member A
chr13_-_59823072 0.449 ENSMUST00000071703.4
 Zcchc6
zinc finger, CCHC domain containing 6
chr5_-_44799643 0.439 ENSMUST00000070748.5
 Ldb2
LIM domain binding 2
chr2_+_130406478 0.429 ENSMUST00000055421.4
 Tmem239
transmembrane 239
chr15_-_12592556 0.428 ENSMUST00000075317.5
 Pdzd2
PDZ domain containing 2
chr6_+_5725639 0.396 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr8_-_36952414 0.389 ENSMUST00000163663.2
 Dlc1
deleted in liver cancer 1
chr3_-_33844255 0.386 ENSMUST00000029222.5
 Ccdc39
coiled-coil domain containing 39
chr4_-_149485157 0.383 ENSMUST00000126896.1
ENSMUST00000105693.1
ENSMUST00000030845.6
 Nmnat1


nicotinamide nucleotide adenylyltransferase 1


chr10_-_122047293 0.370 ENSMUST00000020322.5
ENSMUST00000081688.6
 Srgap1

SLIT-ROBO Rho GTPase activating protein 1

chr14_+_75284343 0.362 ENSMUST00000022577.5
 Zc3h13
zinc finger CCCH type containing 13
chr14_-_15438974 0.360 ENSMUST00000055211.4
 Lrrc3b
leucine rich repeat containing 3B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 90 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.8 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.1 0.7 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.2 0.6 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 0.6 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.2 0.5 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.5 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.5 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 0.5 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.4 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.4 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.4 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.4 GO:0008209 androgen metabolic process(GO:0008209)
0.1 0.3 GO:0070488 neutrophil aggregation(GO:0070488)
0.1 0.3 GO:0032497 detection of lipopolysaccharide(GO:0032497)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.3 GO:0000235 astral microtubule(GO:0000235)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.2 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.0 0.2 GO:0008623 CHRAC(GO:0008623)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.7 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.7 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.4 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.4 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0034945 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-palmitoyltransferase activity(GO:0016416) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.3 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.3 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.3 GO:0050786 arachidonic acid binding(GO:0050544) RAGE receptor binding(GO:0050786)
0.0 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)