Motif ID: Etv1_Etv5_Gabpa

Z-value: 1.933

Transcription factors associated with Etv1_Etv5_Gabpa:

Gene SymbolEntrez IDGene Name
Etv1 ENSMUSG00000004151.10 Etv1
Etv5 ENSMUSG00000013089.9 Etv5
Gabpa ENSMUSG00000008976.10 Gabpa

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Etv1mm10_v2_chr12_+_38783455_38783482-0.924.3e-06Click!
Etv5mm10_v2_chr16_-_22439719_22439733-0.661.0e-02Click!
Gabpamm10_v2_chr16_+_84835070_84835124-0.362.1e-01Click!


Activity profile for motif Etv1_Etv5_Gabpa.

activity profile for motif Etv1_Etv5_Gabpa


Sorted Z-values histogram for motif Etv1_Etv5_Gabpa

Sorted Z-values for motif Etv1_Etv5_Gabpa



Network of associatons between targets according to the STRING database.



First level regulatory network of Etv1_Etv5_Gabpa

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_22161450 5.944 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr15_-_93595877 4.714 ENSMUST00000048982.4
 Prickle1
prickle homolog 1 (Drosophila)
chr7_-_35754394 4.063 ENSMUST00000051377.8
 Dpy19l3
dpy-19-like 3 (C. elegans)
chr2_+_164805082 3.936 ENSMUST00000052107.4
 Zswim3
zinc finger SWIM-type containing 3
chr6_+_5725639 3.523 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr18_-_66860458 3.477 ENSMUST00000057942.2
 Mc4r
melanocortin 4 receptor
chr2_+_5845243 3.332 ENSMUST00000127116.1
 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr9_+_27299205 3.289 ENSMUST00000115247.1
ENSMUST00000133213.1
 Igsf9b

immunoglobulin superfamily, member 9B

chr11_-_84880195 3.271 ENSMUST00000067058.2
ENSMUST00000108080.2
 Pigw

phosphatidylinositol glycan anchor biosynthesis, class W

chr2_-_118256929 3.214 ENSMUST00000028820.6
ENSMUST00000028821.3
 Fsip1

fibrous sheath-interacting protein 1

chr14_-_63543931 3.197 ENSMUST00000058679.5
 Mtmr9
myotubularin related protein 9
chr2_+_73312601 3.152 ENSMUST00000090811.4
ENSMUST00000112050.1
 Scrn3

secernin 3

chr14_-_30626196 3.127 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
 Prkcd


protein kinase C, delta


chr11_+_54522872 3.116 ENSMUST00000108895.1
ENSMUST00000101206.3
 Rapgef6

Rap guanine nucleotide exchange factor (GEF) 6

chr14_-_31494992 2.966 ENSMUST00000055303.3
 Mettl6
methyltransferase like 6
chr1_+_187215501 2.937 ENSMUST00000097443.3
ENSMUST00000065573.7
ENSMUST00000110943.2
ENSMUST00000044812.5
 Gpatch2



G patch domain containing 2



chr11_+_83299005 2.791 ENSMUST00000176944.1
 Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr9_-_105495475 2.780 ENSMUST00000176036.1
 Atp2c1
ATPase, Ca++-sequestering
chr7_+_119793987 2.702 ENSMUST00000033218.8
ENSMUST00000106520.1
 2610020H08Rik

RIKEN cDNA 2610020H08 gene

chr11_+_101732950 2.668 ENSMUST00000039152.7
 Dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 627 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 7.0 GO:0003281 ventricular septum development(GO:0003281)
0.1 5.6 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.1 5.4 GO:0051028 mRNA transport(GO:0051028)
0.3 5.1 GO:0006415 translational termination(GO:0006415)
0.2 5.1 GO:0030033 microvillus assembly(GO:0030033)
1.2 5.0 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.3 5.0 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
1.6 4.7 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.1 4.7 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
1.5 4.6 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.5 4.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 4.6 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.4 4.5 GO:0000012 single strand break repair(GO:0000012)
0.2 4.5 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.2 4.4 GO:0045116 protein neddylation(GO:0045116)
0.4 4.3 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.2 4.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 4.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.4 4.1 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 278 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 12.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.2 9.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 8.4 GO:0031965 nuclear membrane(GO:0031965)
0.4 6.3 GO:0017119 Golgi transport complex(GO:0017119)
0.1 6.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 5.4 GO:0005643 nuclear pore(GO:0005643)
0.0 5.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 5.2 GO:0031966 mitochondrial membrane(GO:0031966)
0.2 4.1 GO:0002102 podosome(GO:0002102)
0.1 4.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.4 4.0 GO:0000812 Swr1 complex(GO:0000812)
0.3 3.9 GO:0031932 TORC2 complex(GO:0031932)
0.2 3.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.5 3.8 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 3.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 3.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 3.6 GO:0031902 late endosome membrane(GO:0031902)
0.1 3.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 3.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 3.6 GO:0045177 apical part of cell(GO:0045177)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 418 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 16.8 GO:0008565 protein transporter activity(GO:0008565)
0.1 10.5 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.2 8.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 8.6 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.4 6.7 GO:0070300 phosphatidic acid binding(GO:0070300)
0.3 6.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 6.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.2 5.5 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.7 5.4 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.3 5.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.6 5.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
1.2 5.0 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 4.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 4.4 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.7 4.0 GO:0034916 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.3 3.9 GO:0031386 protein tag(GO:0031386)
0.1 3.9 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 3.9 GO:0031491 nucleosome binding(GO:0031491)
0.2 3.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 3.8 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)