Motif ID: Etv4

Z-value: 0.510


Transcription factors associated with Etv4:

Gene SymbolEntrez IDGene Name
Etv4 ENSMUSG00000017724.8 Etv4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Etv4mm10_v2_chr11_-_101785252_1017853710.714.3e-03Click!


Activity profile for motif Etv4.

activity profile for motif Etv4


Sorted Z-values histogram for motif Etv4

Sorted Z-values for motif Etv4



Network of associatons between targets according to the STRING database.



First level regulatory network of Etv4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_169685191 1.454 ENSMUST00000112104.1
ENSMUST00000112107.1
 Mid1

midline 1

chr3_+_95526777 1.449 ENSMUST00000015667.2
ENSMUST00000116304.2
 Ctss

cathepsin S

chr7_+_30413744 1.134 ENSMUST00000032800.9
 Tyrobp
TYRO protein tyrosine kinase binding protein
chr10_-_83648713 1.079 ENSMUST00000020500.7
 Appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr2_+_14229390 0.995 ENSMUST00000028045.2
 Mrc1
mannose receptor, C type 1
chr6_-_72390659 0.903 ENSMUST00000059983.9
 Vamp8
vesicle-associated membrane protein 8
chr5_+_111733924 0.831 ENSMUST00000180627.1
 Gm26897
predicted gene, 26897
chr7_-_27181149 0.820 ENSMUST00000071986.6
ENSMUST00000121848.1
 Mia

melanoma inhibitory activity

chr13_-_37049203 0.772 ENSMUST00000037491.8
 F13a1
coagulation factor XIII, A1 subunit
chr6_+_17463749 0.762 ENSMUST00000115443.1
 Met
met proto-oncogene
chr11_+_82035569 0.653 ENSMUST00000000193.5
 Ccl2
chemokine (C-C motif) ligand 2
chr13_-_92030897 0.634 ENSMUST00000149630.1
 Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr11_-_48816936 0.618 ENSMUST00000140800.1
 Trim41
tripartite motif-containing 41
chr8_+_70501116 0.617 ENSMUST00000127983.1
 Crlf1
cytokine receptor-like factor 1
chr6_+_125552948 0.600 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chr10_-_83648631 0.598 ENSMUST00000146876.2
ENSMUST00000176294.1
 Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr16_+_36934976 0.576 ENSMUST00000023531.8
 Hcls1
hematopoietic cell specific Lyn substrate 1
chr6_+_17463826 0.559 ENSMUST00000140070.1
 Met
met proto-oncogene
chr19_-_7019423 0.530 ENSMUST00000040772.8
 Fermt3
fermitin family homolog 3 (Drosophila)
chr1_+_165788746 0.489 ENSMUST00000161559.2
 Cd247
CD247 antigen

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 163 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0010447 response to acidic pH(GO:0010447)
0.1 1.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 1.1 GO:2001204 regulation of osteoclast development(GO:2001204)
0.3 0.9 GO:0090187 zymogen granule exocytosis(GO:0070625) positive regulation of pancreatic juice secretion(GO:0090187)
0.0 0.9 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 0.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.8 GO:0018149 peptide cross-linking(GO:0018149)
0.2 0.7 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.2 0.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.7 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.7 GO:0071353 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.0 0.7 GO:0034605 cellular response to heat(GO:0034605)
0.2 0.6 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.1 0.6 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.6 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.5 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 74 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 1.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.2 0.7 GO:0044299 C-fiber(GO:0044299)
0.2 0.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0042581 specific granule(GO:0042581)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.4 GO:0016460 myosin II complex(GO:0016460)
0.1 0.3 GO:0036488 CHOP-C/EBP complex(GO:0036488)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 86 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.5 GO:0001968 fibronectin binding(GO:0001968)
0.3 1.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 1.1 GO:0008083 growth factor activity(GO:0008083)
0.1 1.0 GO:0005537 mannose binding(GO:0005537)
0.1 0.9 GO:0019865 immunoglobulin binding(GO:0019865)
0.2 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.8 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.8 GO:0000049 tRNA binding(GO:0000049)
0.2 0.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.7 GO:0008430 selenium binding(GO:0008430)
0.0 0.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.1 0.5 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)