Motif ID: Etv6

Z-value: 1.020


Transcription factors associated with Etv6:

Gene SymbolEntrez IDGene Name
Etv6 ENSMUSG00000030199.10 Etv6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Etv6mm10_v2_chr6_+_134035953_1340359730.602.2e-02Click!


Activity profile for motif Etv6.

activity profile for motif Etv6


Sorted Z-values histogram for motif Etv6

Sorted Z-values for motif Etv6



Network of associatons between targets according to the STRING database.



First level regulatory network of Etv6

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_20090538 1.253 ENSMUST00000072519.5
 Elmo1
engulfment and cell motility 1
chr13_+_20090500 1.156 ENSMUST00000165249.2
 Elmo1
engulfment and cell motility 1
chr1_+_33669816 1.032 ENSMUST00000051203.5
 1700001G17Rik
RIKEN cDNA 1700001G17 gene
chr1_+_179546303 0.991 ENSMUST00000040706.8
 Cnst
consortin, connexin sorting protein
chr1_-_183221529 0.944 ENSMUST00000003035.5
 Disp1
dispatched homolog 1 (Drosophila)
chr3_-_89764581 0.911 ENSMUST00000029562.3
 Chrnb2
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr1_+_74601441 0.904 ENSMUST00000087183.4
ENSMUST00000148456.1
ENSMUST00000113694.1
 Stk36


serine/threonine kinase 36


chr5_+_124629050 0.879 ENSMUST00000037865.8
 Atp6v0a2
ATPase, H+ transporting, lysosomal V0 subunit A2
chr1_-_36244245 0.871 ENSMUST00000046875.7
 Uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr9_+_65032722 0.812 ENSMUST00000167773.1
 Dpp8
dipeptidylpeptidase 8
chr5_+_143758293 0.801 ENSMUST00000180951.1
 D130017N08Rik
RIKEN cDNA D130017N08 gene
chr18_+_62548911 0.798 ENSMUST00000055725.4
ENSMUST00000162365.1
 Spink10

serine peptidase inhibitor, Kazal type 10

chr3_-_95871367 0.733 ENSMUST00000142437.1
ENSMUST00000067298.4
 Mrps21

mitochondrial ribosomal protein S21

chr10_-_67285180 0.732 ENSMUST00000159002.1
ENSMUST00000077839.6
 Nrbf2

nuclear receptor binding factor 2

chrX_-_94212638 0.719 ENSMUST00000113922.1
 Eif2s3x
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr15_-_98145698 0.704 ENSMUST00000123626.1
 Asb8
ankyrin repeat and SOCS box-containing 8
chr15_-_98145625 0.698 ENSMUST00000059112.5
 Asb8
ankyrin repeat and SOCS box-containing 8
chr12_+_102757965 0.671 ENSMUST00000046404.6
 Ubr7
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr17_+_35135463 0.661 ENSMUST00000173535.1
ENSMUST00000173952.1
 Bag6

BCL2-associated athanogene 6

chr1_+_74601548 0.643 ENSMUST00000087186.4
 Stk36
serine/threonine kinase 36

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 98 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 2.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 1.7 GO:0008643 carbohydrate transport(GO:0008643)
0.2 1.6 GO:0036506 maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.4 1.5 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 1.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 1.0 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.1 1.0 GO:0031053 production of siRNA involved in RNA interference(GO:0030422) primary miRNA processing(GO:0031053)
0.1 1.0 GO:0045116 protein neddylation(GO:0045116)
0.3 0.9 GO:0060084 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) synaptic transmission involved in micturition(GO:0060084)
0.1 0.9 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.9 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.9 GO:0060539 diaphragm development(GO:0060539)
0.2 0.8 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1 0.8 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.2 0.7 GO:0019085 early viral transcription(GO:0019085)
0.0 0.7 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.7 GO:0032543 mitochondrial translation(GO:0032543)
0.2 0.6 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.6 GO:0010847 regulation of chromatin assembly(GO:0010847)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 1.6 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 1.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3 1.0 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.8 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.7 GO:0071439 clathrin complex(GO:0071439)
0.1 0.7 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.7 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.7 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.6 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.6 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.4 1.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 1.6 GO:0070628 proteasome binding(GO:0070628)
0.1 1.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 1.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.2 GO:0031386 protein tag(GO:0031386)
0.0 1.2 GO:0051082 unfolded protein binding(GO:0051082)
0.2 1.0 GO:0071253 connexin binding(GO:0071253)
0.0 1.0 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.9 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.1 0.9 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.9 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.9 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 0.8 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)