Motif ID: Evx2

Z-value: 1.011


Transcription factors associated with Evx2:

Gene SymbolEntrez IDGene Name
Evx2 ENSMUSG00000001815.9 Evx2



Activity profile for motif Evx2.

activity profile for motif Evx2


Sorted Z-values histogram for motif Evx2

Sorted Z-values for motif Evx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Evx2

PNG image of the network

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Top targets:


Showing 1 to 20 of 73 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_17402672 3.446 ENSMUST00000115576.2
 Lix1
limb expression 1 homolog (chicken)
chr2_+_154548888 2.730 ENSMUST00000045116.4
ENSMUST00000109709.3
 1700003F12Rik

RIKEN cDNA 1700003F12 gene

chrX_-_60893430 2.250 ENSMUST00000135107.2
 Sox3
SRY-box containing gene 3
chr2_-_168767136 1.529 ENSMUST00000029061.5
ENSMUST00000103074.1
 Sall4

sal-like 4 (Drosophila)

chr4_+_102570065 1.390 ENSMUST00000097950.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr2_+_91256813 1.034 ENSMUST00000144394.1
ENSMUST00000028694.5
ENSMUST00000168916.1
ENSMUST00000156919.1
 Pacsin3



protein kinase C and casein kinase substrate in neurons 3



chr2_+_91257323 1.012 ENSMUST00000111349.2
ENSMUST00000131711.1
 Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr4_-_132075250 0.961 ENSMUST00000105970.1
ENSMUST00000105975.1
 Epb4.1

erythrocyte protein band 4.1

chr5_-_84417359 0.941 ENSMUST00000113401.1
 Epha5
Eph receptor A5
chr11_+_75532099 0.872 ENSMUST00000169547.2
 Slc43a2
solute carrier family 43, member 2
chr6_+_72097561 0.852 ENSMUST00000069994.4
ENSMUST00000114112.1
 St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chr9_-_66514567 0.789 ENSMUST00000056890.8
 Fbxl22
F-box and leucine-rich repeat protein 22
chr10_+_80264942 0.740 ENSMUST00000105362.1
ENSMUST00000105361.3
 Dazap1

DAZ associated protein 1

chr2_-_132247747 0.740 ENSMUST00000110163.1
ENSMUST00000180286.1
ENSMUST00000028816.2
 Tmem230


transmembrane protein 230


chr12_-_98577940 0.731 ENSMUST00000110113.1
 Kcnk10
potassium channel, subfamily K, member 10
chr16_-_45724600 0.708 ENSMUST00000096057.4
 Tagln3
transgelin 3
chr14_+_48446128 0.693 ENSMUST00000124720.1
 Tmem260
transmembrane protein 260
chr9_+_47530173 0.677 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
 Cadm1





cell adhesion molecule 1





chr11_+_116843278 0.676 ENSMUST00000106370.3
 Mettl23
methyltransferase like 23
chr17_+_36837123 0.670 ENSMUST00000179968.1
ENSMUST00000130367.1
ENSMUST00000130801.1
ENSMUST00000144182.1
ENSMUST00000123715.1
ENSMUST00000053434.8
 Trim26





tripartite motif-containing 26






Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.4 GO:0097352 autophagosome maturation(GO:0097352)
0.1 2.2 GO:0007530 sex determination(GO:0007530)
0.1 2.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 2.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.4 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.9 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.8 GO:0015807 L-amino acid transport(GO:0015807)
0.2 0.7 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.7 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.6 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.6 GO:1901998 toxin transport(GO:1901998)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.5 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.4 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.3 GO:0046469 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 GO:0000792 heterochromatin(GO:0000792)
0.1 1.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.7 GO:0070852 cell body fiber(GO:0070852)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.1 0.6 GO:0033503 HULC complex(GO:0033503)
0.1 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.4 GO:0031672 A band(GO:0031672)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0005640 nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular_function category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 2.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 1.4 GO:0030552 cAMP binding(GO:0030552)
0.1 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.7 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.5 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.4 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)