Motif ID: Fos

Z-value: 0.891


Transcription factors associated with Fos:

Gene SymbolEntrez IDGene Name
Fos ENSMUSG00000021250.7 Fos

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosmm10_v2_chr12_+_85473883_85473896-0.771.3e-03Click!


Activity profile for motif Fos.

activity profile for motif Fos


Sorted Z-values histogram for motif Fos

Sorted Z-values for motif Fos



Network of associatons between targets according to the STRING database.



First level regulatory network of Fos

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_64090265 4.577 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr10_-_64090241 4.569 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr14_-_12345847 4.044 ENSMUST00000022262.4
 Fezf2
Fez family zinc finger 2
chr13_-_56296551 3.771 ENSMUST00000021970.9
 Cxcl14
chemokine (C-X-C motif) ligand 14
chr3_+_103576081 3.492 ENSMUST00000183637.1
ENSMUST00000117221.2
ENSMUST00000118117.1
ENSMUST00000118563.2
 Syt6



synaptotagmin VI



chr3_+_123267445 2.682 ENSMUST00000047923.7
 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr2_+_13573927 1.941 ENSMUST00000141365.1
ENSMUST00000028062.2
 Vim

vimentin

chr18_+_82910863 1.923 ENSMUST00000171238.1
 Zfp516
zinc finger protein 516
chr2_-_151632471 1.480 ENSMUST00000137936.1
ENSMUST00000146172.1
ENSMUST00000094456.3
ENSMUST00000148755.1
ENSMUST00000109875.1
ENSMUST00000028951.7
ENSMUST00000109877.3
 Snph






syntaphilin






chr11_-_84067063 1.439 ENSMUST00000108101.1
 Dusp14
dual specificity phosphatase 14
chr2_+_20737306 1.341 ENSMUST00000114606.1
ENSMUST00000114608.1
 Etl4

enhancer trap locus 4

chr11_-_84068766 1.268 ENSMUST00000018792.5
 Dusp14
dual specificity phosphatase 14
chr8_+_36489191 1.090 ENSMUST00000171777.1
 6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr2_-_76215363 1.086 ENSMUST00000144892.1
 Pde11a
phosphodiesterase 11A
chr16_-_44558864 1.030 ENSMUST00000023370.4
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr9_+_114978507 1.006 ENSMUST00000183104.1
 Osbpl10
oxysterol binding protein-like 10
chr11_-_84069179 0.979 ENSMUST00000138208.1
 Dusp14
dual specificity phosphatase 14
chr2_-_166581969 0.971 ENSMUST00000109246.1
 Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr18_+_32938955 0.966 ENSMUST00000042868.4
 Camk4
calcium/calmodulin-dependent protein kinase IV
chr8_-_61591130 0.906 ENSMUST00000135439.1
ENSMUST00000121200.1
 Palld

palladin, cytoskeletal associated protein


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 113 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 9.5 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.7 4.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.3 3.8 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 3.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
1.2 3.5 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.4 1.9 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 1.9 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 1.9 GO:0009409 response to cold(GO:0009409)
0.4 1.8 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 1.5 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.5 1.4 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 1.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.4 1.1 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.1 1.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 1.0 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.3 0.9 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 0.9 GO:0034720 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) histone H3-K4 demethylation(GO:0034720) mammary duct terminal end bud growth(GO:0060763)
0.1 0.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 2.8 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.5 GO:0043198 dendritic shaft(GO:0043198)
0.1 2.1 GO:0097440 apical dendrite(GO:0097440)
0.0 2.1 GO:0055037 recycling endosome(GO:0055037)
0.5 1.9 GO:0045098 type III intermediate filament(GO:0045098)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.9 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.2 0.8 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.1 0.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.7 GO:0031105 septin complex(GO:0031105)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.6 GO:0008623 CHRAC(GO:0008623)
0.1 0.6 GO:0005883 neurofilament(GO:0005883)
0.2 0.5 GO:1990047 spindle matrix(GO:1990047)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.8 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 3.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 3.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 3.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.7 GO:0008009 chemokine activity(GO:0008009)
0.0 2.4 GO:0022832 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.5 2.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 1.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.5 GO:0005521 lamin binding(GO:0005521)
0.0 1.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.2 1.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 1.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 1.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.1 GO:0030553 cGMP binding(GO:0030553)
0.0 1.1 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 1.0 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.3 0.9 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)