Motif ID: Fosl2_Bach2
Z-value: 0.771
Transcription factors associated with Fosl2_Bach2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Bach2 | ENSMUSG00000040270.10 | Bach2 |
| Fosl2 | ENSMUSG00000029135.9 | Fosl2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Bach2 | mm10_v2_chr4_+_32238950_32238964 | 0.80 | 5.9e-04 | Click! |
| Fosl2 | mm10_v2_chr5_+_32136458_32136505 | 0.72 | 3.7e-03 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 108 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 9.4 | GO:1902993 | positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993) |
| 0.2 | 5.2 | GO:0045663 | positive regulation of myoblast differentiation(GO:0045663) |
| 0.1 | 3.7 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 3.2 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.2 | 1.9 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.0 | 1.9 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
| 0.3 | 1.8 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
| 0.2 | 1.8 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.1 | 1.7 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.4 | 1.5 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 0.2 | 1.5 | GO:0034720 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) histone H3-K4 demethylation(GO:0034720) mammary duct terminal end bud growth(GO:0060763) |
| 0.1 | 1.5 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
| 0.1 | 1.4 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.4 | 1.3 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
| 0.1 | 1.3 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.0 | 1.3 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.4 | 1.2 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
| 0.1 | 1.2 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.1 | 1.2 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.1 | 1.2 | GO:0008063 | Toll signaling pathway(GO:0008063) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 57 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 15.7 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 5.6 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.1 | 3.2 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 3.2 | GO:0036464 | cytoplasmic ribonucleoprotein granule(GO:0036464) |
| 0.0 | 2.1 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.1 | 1.9 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.4 | 1.6 | GO:0031673 | H zone(GO:0031673) |
| 0.2 | 1.6 | GO:0005883 | neurofilament(GO:0005883) |
| 0.1 | 1.6 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.4 | 1.5 | GO:0043259 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
| 0.1 | 1.5 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.2 | 1.2 | GO:0008623 | CHRAC(GO:0008623) |
| 0.1 | 1.2 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.1 | 1.1 | GO:0031105 | septin complex(GO:0031105) |
| 0.0 | 1.1 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 1.0 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 0.9 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.0 | 0.9 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.2 | 0.8 | GO:0045098 | type III intermediate filament(GO:0045098) |
| 0.1 | 0.8 | GO:0031094 | platelet dense tubular network(GO:0031094) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 81 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.9 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.1 | 3.7 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.1 | 3.2 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 3.1 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 2.5 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.1 | 1.9 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.3 | 1.8 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.0 | 1.8 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.1 | 1.6 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.5 | 1.5 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.2 | 1.5 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.2 | 1.5 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.1 | 1.5 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.1 | 1.4 | GO:0030553 | cGMP binding(GO:0030553) |
| 0.4 | 1.3 | GO:1990450 | linear polyubiquitin binding(GO:1990450) |
| 0.2 | 1.2 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.1 | 1.2 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 1.2 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.2 | 1.0 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.1 | 1.0 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
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