Motif ID: Foxa3

Z-value: 1.242


Transcription factors associated with Foxa3:

Gene SymbolEntrez IDGene Name
Foxa3 ENSMUSG00000040891.5 Foxa3



Activity profile for motif Foxa3.

activity profile for motif Foxa3


Sorted Z-values histogram for motif Foxa3

Sorted Z-values for motif Foxa3



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxa3

PNG image of the network

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Top targets:


Showing 1 to 20 of 145 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_91269759 10.382 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr2_-_77519565 4.583 ENSMUST00000111830.2
 Zfp385b
zinc finger protein 385B
chr15_+_3270767 4.389 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr3_-_87263518 3.195 ENSMUST00000090986.4
 Fcrls
Fc receptor-like S, scavenger receptor
chr1_+_51289106 2.895 ENSMUST00000051572.6
 Sdpr
serum deprivation response
chr3_-_144202300 2.831 ENSMUST00000121796.1
ENSMUST00000121112.1
 Lmo4

LIM domain only 4

chr15_-_54919961 2.812 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
 Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr13_+_94173992 2.615 ENSMUST00000121618.1
 Lhfpl2
lipoma HMGIC fusion partner-like 2
chr15_-_54920115 2.367 ENSMUST00000171545.1
 Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr7_-_27181149 2.300 ENSMUST00000071986.6
ENSMUST00000121848.1
 Mia

melanoma inhibitory activity

chr10_-_128744014 2.290 ENSMUST00000026414.7
 Dgka
diacylglycerol kinase, alpha
chr2_-_84425258 2.141 ENSMUST00000074262.2
 Calcrl
calcitonin receptor-like
chrX_+_142228177 2.035 ENSMUST00000112914.1
 Nxt2
nuclear transport factor 2-like export factor 2
chr1_+_165763746 2.006 ENSMUST00000111432.3
 Creg1
cellular repressor of E1A-stimulated genes 1
chr13_-_96542479 1.966 ENSMUST00000022172.4
 Polk
polymerase (DNA directed), kappa
chr3_-_87263703 1.944 ENSMUST00000146512.1
 Fcrls
Fc receptor-like S, scavenger receptor
chr6_-_137571007 1.937 ENSMUST00000100841.2
 Eps8
epidermal growth factor receptor pathway substrate 8
chrX_+_142227923 1.822 ENSMUST00000042329.5
 Nxt2
nuclear transport factor 2-like export factor 2
chr11_+_78499087 1.753 ENSMUST00000017488.4
 Vtn
vitronectin
chr11_-_26210553 1.710 ENSMUST00000101447.3
 5730522E02Rik
RIKEN cDNA 5730522E02 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.6 GO:0048663 neuron fate commitment(GO:0048663)
0.7 5.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.6 4.4 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 3.9 GO:0051028 mRNA transport(GO:0051028)
0.0 3.6 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.2 2.8 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.5 2.5 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.8 2.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 2.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 2.2 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.5 2.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.3 2.0 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.5 1.9 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 1.8 GO:0097421 liver regeneration(GO:0097421)
0.3 1.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.5 1.6 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.5 1.6 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 1.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.4 1.5 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 14.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.7 GO:0005901 caveola(GO:0005901)
0.0 2.5 GO:0005902 microvillus(GO:0005902)
0.0 2.5 GO:0000786 nucleosome(GO:0000786)
0.0 2.5 GO:0031965 nuclear membrane(GO:0031965)
0.2 2.2 GO:0030478 actin cap(GO:0030478)
0.1 1.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.4 1.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 1.8 GO:0032432 actin filament bundle(GO:0032432)
0.3 1.6 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.2 GO:0043204 perikaryon(GO:0043204)
0.1 1.1 GO:0043219 catenin complex(GO:0016342) lateral loop(GO:0043219)
0.1 1.0 GO:0097433 dense body(GO:0097433)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 5.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.3 4.4 GO:0008430 selenium binding(GO:0008430)
0.0 4.4 GO:0002039 p53 binding(GO:0002039)
0.0 3.5 GO:0035326 enhancer binding(GO:0035326)
0.1 2.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 2.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 2.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.5 2.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.2 2.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 2.0 GO:0010181 FMN binding(GO:0010181)
0.1 2.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 1.8 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 1.6 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.6 GO:0031005 filamin binding(GO:0031005)
0.0 1.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2 1.5 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 1.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 1.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)