Motif ID: Foxa3
Z-value: 1.242
Transcription factors associated with Foxa3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Foxa3 | ENSMUSG00000040891.5 | Foxa3 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 2.3 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.7 | 5.2 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.6 | 4.4 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.5 | 1.6 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
| 0.5 | 2.1 | GO:0034285 | response to sucrose(GO:0009744) response to disaccharide(GO:0034285) |
| 0.5 | 1.6 | GO:1900158 | negative regulation of bone mineralization involved in bone maturation(GO:1900158) |
| 0.5 | 2.5 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 0.5 | 1.9 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.4 | 1.5 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.4 | 1.1 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
| 0.3 | 2.0 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
| 0.3 | 1.7 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.3 | 1.1 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
| 0.3 | 0.8 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
| 0.2 | 0.9 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.2 | 1.1 | GO:0060066 | oviduct development(GO:0060066) |
| 0.2 | 2.8 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
| 0.2 | 0.6 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.2 | 0.6 | GO:0034310 | primary alcohol catabolic process(GO:0034310) |
| 0.2 | 0.7 | GO:0031509 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
| 0.2 | 1.8 | GO:0097421 | liver regeneration(GO:0097421) |
| 0.1 | 0.9 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.1 | 1.3 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.1 | 1.3 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.1 | 1.0 | GO:0070447 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) |
| 0.1 | 0.9 | GO:0007343 | egg activation(GO:0007343) |
| 0.1 | 0.5 | GO:0010920 | negative regulation of inositol phosphate biosynthetic process(GO:0010920) |
| 0.1 | 10.6 | GO:0048663 | neuron fate commitment(GO:0048663) |
| 0.1 | 0.7 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
| 0.1 | 0.4 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.1 | 1.2 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.1 | 0.9 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.1 | 0.7 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.1 | 1.4 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.1 | 0.4 | GO:0050812 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 0.1 | 0.8 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.1 | 0.3 | GO:0006553 | lysine metabolic process(GO:0006553) |
| 0.1 | 2.3 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.1 | 0.4 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.1 | 0.5 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) hydrogen sulfide biosynthetic process(GO:0070814) |
| 0.1 | 0.2 | GO:0043651 | linoleic acid metabolic process(GO:0043651) |
| 0.1 | 0.5 | GO:0042573 | retinoic acid metabolic process(GO:0042573) |
| 0.1 | 1.2 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 0.1 | 0.8 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
| 0.1 | 1.6 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.1 | 1.0 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.1 | 0.3 | GO:1901837 | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
| 0.0 | 0.6 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.0 | 0.6 | GO:0032695 | negative regulation of interleukin-12 production(GO:0032695) |
| 0.0 | 0.7 | GO:1901028 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901028) |
| 0.0 | 2.2 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
| 0.0 | 0.4 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.0 | 0.2 | GO:0015803 | branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) |
| 0.0 | 3.6 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
| 0.0 | 0.2 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.0 | 1.4 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.1 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.0 | 0.3 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.0 | 3.9 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.0 | 0.9 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.0 | 0.5 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 0.0 | 0.1 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
| 0.0 | 0.5 | GO:0006625 | protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.0 | 0.4 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.0 | 0.6 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.8 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.3 | 1.6 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.2 | 2.2 | GO:0030478 | actin cap(GO:0030478) |
| 0.1 | 0.4 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.1 | 1.3 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.1 | 1.0 | GO:0097433 | dense body(GO:0097433) |
| 0.1 | 0.4 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.1 | 1.9 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 1.1 | GO:0043219 | catenin complex(GO:0016342) lateral loop(GO:0043219) |
| 0.1 | 0.2 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.8 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.0 | 0.3 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 2.5 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 14.7 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 1.5 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 2.5 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 0.4 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 2.7 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 1.6 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 1.8 | GO:0032432 | actin filament bundle(GO:0032432) |
| 0.0 | 0.4 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 1.0 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.6 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 2.5 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.0 | 0.2 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 1.2 | GO:0043204 | perikaryon(GO:0043204) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 5.2 | GO:0004528 | phosphodiesterase I activity(GO:0004528) |
| 0.5 | 2.1 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.3 | 4.4 | GO:0008430 | selenium binding(GO:0008430) |
| 0.3 | 1.6 | GO:0033192 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.2 | 1.5 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.2 | 2.3 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.2 | 2.1 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
| 0.2 | 0.6 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.2 | 1.4 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 0.1 | 1.0 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.1 | 2.0 | GO:0010181 | FMN binding(GO:0010181) |
| 0.1 | 1.8 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.1 | 0.4 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.1 | 1.0 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 0.1 | 2.9 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.1 | 0.4 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.1 | 1.7 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.1 | 1.6 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 1.1 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.1 | 1.3 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.1 | 1.2 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.1 | 0.8 | GO:0001846 | opsonin binding(GO:0001846) |
| 0.1 | 2.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 2.0 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 0.2 | GO:0071568 | UFM1 transferase activity(GO:0071568) |
| 0.1 | 0.9 | GO:0070636 | single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694) |
| 0.1 | 0.8 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.1 | 0.7 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.1 | 0.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 4.4 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.8 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
| 0.0 | 0.8 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.0 | 0.2 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.0 | 0.7 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 1.6 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.0 | 1.9 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 1.3 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 0.3 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.0 | 3.5 | GO:0035326 | enhancer binding(GO:0035326) |
| 0.0 | 0.5 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.2 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 0.4 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.3 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.1 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.0 | 0.4 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.3 | GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) |
