Motif ID: Foxb1

Z-value: 1.376


Transcription factors associated with Foxb1:

Gene SymbolEntrez IDGene Name
Foxb1 ENSMUSG00000059246.4 Foxb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxb1mm10_v2_chr9_-_69760924_697609400.421.3e-01Click!


Activity profile for motif Foxb1.

activity profile for motif Foxb1


Sorted Z-values histogram for motif Foxb1

Sorted Z-values for motif Foxb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 94 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_14901344 4.403 ENSMUST00000115477.1
 Foxp2
forkhead box P2
chr1_-_158814469 3.921 ENSMUST00000161589.2
 Pappa2
pappalysin 2
chr6_+_14901440 3.418 ENSMUST00000128567.1
 Foxp2
forkhead box P2
chr4_+_102430047 3.233 ENSMUST00000172616.1
 Pde4b
phosphodiesterase 4B, cAMP specific
chr18_-_47333311 3.147 ENSMUST00000126684.1
ENSMUST00000156422.1
 Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr15_-_48791933 2.959 ENSMUST00000160658.1
ENSMUST00000100670.3
ENSMUST00000162830.1
 Csmd3


CUB and Sushi multiple domains 3


chr6_+_8520008 2.953 ENSMUST00000162567.1
ENSMUST00000161217.1
 Glcci1

glucocorticoid induced transcript 1

chr2_+_55437100 2.945 ENSMUST00000112633.2
ENSMUST00000112632.1
 Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr6_-_56362356 2.741 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
 Pde1c



phosphodiesterase 1C



chr1_-_72536930 2.662 ENSMUST00000047786.5
 March4
membrane-associated ring finger (C3HC4) 4
chr2_-_45110336 2.375 ENSMUST00000028229.6
ENSMUST00000152232.1
 Zeb2

zinc finger E-box binding homeobox 2

chrX_+_41401128 2.320 ENSMUST00000115103.2
 Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr10_+_37139558 2.217 ENSMUST00000062667.3
 5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr15_-_11905609 2.216 ENSMUST00000066529.3
 Npr3
natriuretic peptide receptor 3
chrX_-_43274786 2.060 ENSMUST00000016294.7
 Tenm1
teneurin transmembrane protein 1
chr1_-_156034826 1.977 ENSMUST00000141878.1
ENSMUST00000123705.1
 Tor1aip1

torsin A interacting protein 1

chr5_-_51567717 1.936 ENSMUST00000127135.1
ENSMUST00000151104.1
 Ppargc1a

peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

chr1_+_179546303 1.853 ENSMUST00000040706.8
 Cnst
consortin, connexin sorting protein
chr11_-_107348130 1.767 ENSMUST00000134763.1
 Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr10_+_69925484 1.764 ENSMUST00000182692.1
ENSMUST00000092433.5
 Ank3

ankyrin 3, epithelial


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 6.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.5 6.1 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 3.9 GO:0060349 bone morphogenesis(GO:0060349)
0.2 3.2 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 3.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 2.9 GO:0010107 potassium ion import(GO:0010107)
0.2 2.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 2.6 GO:0015693 magnesium ion transport(GO:0015693)
0.4 2.4 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 2.3 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 2.3 GO:0006342 chromatin silencing(GO:0006342)
0.4 2.2 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 2.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.2 2.0 GO:0071763 nuclear membrane organization(GO:0071763)
0.6 1.9 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.6 1.9 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.6 1.7 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3 1.6 GO:0046684 response to pyrethroid(GO:0046684)
0.2 1.6 GO:0098907 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.1 1.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 6.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 3.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 2.9 GO:0030315 T-tubule(GO:0030315)
0.0 2.7 GO:0005795 Golgi stack(GO:0005795)
0.1 2.6 GO:0097440 apical dendrite(GO:0097440)
0.2 2.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.7 GO:0070852 cell body fiber(GO:0070852)
0.1 1.6 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 1.6 GO:0031430 M band(GO:0031430)
0.1 1.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.8 GO:0044291 cell-cell contact zone(GO:0044291)
0.2 0.7 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 7.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 5.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 3.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 3.2 GO:0030552 cAMP binding(GO:0030552)
0.1 3.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.6 2.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4 2.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 2.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 2.4 GO:0070412 R-SMAD binding(GO:0070412)
0.3 2.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.4 2.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 2.0 GO:0005521 lamin binding(GO:0005521)
0.4 1.9 GO:0071253 connexin binding(GO:0071253)
0.1 1.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 1.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 1.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.6 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.9 GO:0017081 chloride channel regulator activity(GO:0017081)