Motif ID: Foxc1

Z-value: 1.161


Transcription factors associated with Foxc1:

Gene SymbolEntrez IDGene Name
Foxc1 ENSMUSG00000050295.2 Foxc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxc1mm10_v2_chr13_+_31806627_318066500.322.7e-01Click!


Activity profile for motif Foxc1.

activity profile for motif Foxc1


Sorted Z-values histogram for motif Foxc1

Sorted Z-values for motif Foxc1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxc1

PNG image of the network

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Top targets:


Showing 1 to 20 of 156 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_+_1010543 6.183 ENSMUST00000091197.3
 Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr3_-_87263518 2.785 ENSMUST00000090986.4
 Fcrls
Fc receptor-like S, scavenger receptor
chr3_-_87263703 2.031 ENSMUST00000146512.1
 Fcrls
Fc receptor-like S, scavenger receptor
chr11_-_78550777 1.559 ENSMUST00000103242.4
 Tmem97
transmembrane protein 97
chr15_+_78597047 1.552 ENSMUST00000043069.5
 Cyth4
cytohesin 4
chr9_-_103222063 1.416 ENSMUST00000170904.1
 Trf
transferrin
chrY_+_90843934 1.273 ENSMUST00000178550.1
 Gm21742
predicted gene, 21742
chr18_+_33464163 1.259 ENSMUST00000097634.3
 Gm10549
predicted gene 10549
chr1_-_87394721 1.246 ENSMUST00000113212.3
 Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr15_-_58034289 1.202 ENSMUST00000100655.3
 9130401M01Rik
RIKEN cDNA 9130401M01 gene
chr13_-_29984219 1.007 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr5_-_70842617 1.004 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr1_+_45311538 0.987 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr7_-_51862216 0.927 ENSMUST00000169357.1
 Fancf
Fanconi anemia, complementation group F
chr17_+_16972910 0.926 ENSMUST00000071374.5
 BC002059
cDNA sequence BC002059
chrX_-_109013389 0.922 ENSMUST00000033597.8
 Hmgn5
high-mobility group nucleosome binding domain 5
chr9_-_60838200 0.914 ENSMUST00000063858.7
 Gm9869
predicted gene 9869
chr5_-_77115145 0.880 ENSMUST00000081964.5
 Hopx
HOP homeobox
chr3_+_95124476 0.870 ENSMUST00000131597.1
ENSMUST00000005769.6
ENSMUST00000107227.1
 Tmod4


tropomodulin 4


chr14_-_48662740 0.852 ENSMUST00000122009.1
 Otx2
orthodenticle homolog 2 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.6 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.2 1.4 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.0 1.2 GO:0010107 potassium ion import(GO:0010107)
0.1 1.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 1.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 1.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.9 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.9 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 0.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.9 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.2 0.7 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.1 0.7 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.1 0.6 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282)
0.1 0.6 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.6 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.2 0.5 GO:0003104 positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) hematopoietic stem cell migration(GO:0035701) dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510) regulation of dendritic cell apoptotic process(GO:2000668)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 1.4 GO:0097433 dense body(GO:0097433)
0.0 1.2 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.0 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.2 0.6 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.5 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.3 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613) Flemming body(GO:0090543)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 1.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 1.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 1.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.0 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917) GABA receptor binding(GO:0050811)
0.1 0.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.6 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.6 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.6 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296) receptor agonist activity(GO:0048018)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.5 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.5 GO:0030546 receptor activator activity(GO:0030546)
0.0 0.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)