Motif ID: Foxd1

Z-value: 1.486


Transcription factors associated with Foxd1:

Gene SymbolEntrez IDGene Name
Foxd1 ENSMUSG00000078302.3 Foxd1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxd1mm10_v2_chr13_+_98354234_983542500.431.3e-01Click!


Activity profile for motif Foxd1.

activity profile for motif Foxd1


Sorted Z-values histogram for motif Foxd1

Sorted Z-values for motif Foxd1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxd1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_46294592 11.114 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr4_+_144892813 8.450 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr4_+_144893077 7.072 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chrX_+_169685191 6.281 ENSMUST00000112104.1
ENSMUST00000112107.1
 Mid1

midline 1

chr15_+_3270767 6.116 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr8_+_65618009 5.924 ENSMUST00000110258.1
ENSMUST00000110256.1
ENSMUST00000110255.1
 March1


membrane-associated ring finger (C3HC4) 1


chr3_+_118430299 5.873 ENSMUST00000180774.1
 Gm26871
predicted gene, 26871
chr3_+_5218546 5.742 ENSMUST00000026284.6
 Zfhx4
zinc finger homeodomain 4
chr4_+_144893127 5.369 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr6_+_30541582 5.177 ENSMUST00000096066.4
 Cpa2
carboxypeptidase A2, pancreatic
chr3_+_52268337 4.893 ENSMUST00000053764.5
 Foxo1
forkhead box O1
chr14_-_55560340 4.079 ENSMUST00000066106.3
 A730061H03Rik
RIKEN cDNA A730061H03 gene
chr7_-_142372210 4.053 ENSMUST00000084412.5
 Ifitm10
interferon induced transmembrane protein 10
chr3_-_144205165 3.926 ENSMUST00000120539.1
 Lmo4
LIM domain only 4
chr3_+_5218516 3.814 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4
chr18_+_69344503 3.812 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr2_+_128126030 3.480 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
 Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr3_+_34649987 3.267 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr3_-_144202300 3.114 ENSMUST00000121796.1
ENSMUST00000121112.1
 Lmo4

LIM domain only 4

chr8_+_31091593 3.001 ENSMUST00000161713.1
 Dusp26
dual specificity phosphatase 26 (putative)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 104 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 20.9 GO:0042572 retinol metabolic process(GO:0042572)
0.6 11.6 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.5 7.0 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.2 6.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.9 6.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.3 5.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.2 5.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.6 4.9 GO:0071732 cellular response to nitric oxide(GO:0071732)
1.0 4.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.4 3.8 GO:0042118 endothelial cell activation(GO:0042118)
0.3 3.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 3.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 3.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 3.6 GO:0006270 DNA replication initiation(GO:0006270)
0.5 3.3 GO:0021984 adenohypophysis development(GO:0021984) olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.6 3.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.0 3.0 GO:1901254 positive regulation of intracellular transport of viral material(GO:1901254)
1.0 3.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.7 2.9 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.2 2.9 GO:0051150 regulation of smooth muscle cell differentiation(GO:0051150)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 28.4 GO:0005667 transcription factor complex(GO:0005667)
0.2 5.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.8 3.8 GO:0097149 centralspindlin complex(GO:0097149)
0.3 3.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.4 3.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.3 3.3 GO:0031931 TORC1 complex(GO:0031931)
1.0 3.0 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.3 2.8 GO:0030478 actin cap(GO:0030478)
0.1 2.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.4 2.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 2.3 GO:0005874 microtubule(GO:0005874)
0.0 2.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.5 2.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 2.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 2.0 GO:0031526 brush border membrane(GO:0031526)
0.0 1.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.7 GO:0043204 perikaryon(GO:0043204)
0.0 1.6 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.4 GO:0031209 SCAR complex(GO:0031209)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 78 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.0 20.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 12.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.3 6.2 GO:0042287 MHC protein binding(GO:0042287)
0.4 6.1 GO:0008430 selenium binding(GO:0008430)
0.3 5.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 5.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 4.9 GO:0001223 transcription coactivator binding(GO:0001223)
1.0 3.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 3.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 3.5 GO:0045502 dynein binding(GO:0045502)
0.2 3.3 GO:0035198 miRNA binding(GO:0035198)
1.0 3.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.6 3.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 3.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.7 2.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 2.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 2.7 GO:0070888 E-box binding(GO:0070888)
0.1 2.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.4 2.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 2.3 GO:0032036 myosin heavy chain binding(GO:0032036)