Motif ID: Foxd2

Z-value: 0.518


Transcription factors associated with Foxd2:

Gene SymbolEntrez IDGene Name
Foxd2 ENSMUSG00000055210.3 Foxd2



Activity profile for motif Foxd2.

activity profile for motif Foxd2


Sorted Z-values histogram for motif Foxd2

Sorted Z-values for motif Foxd2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxd2

PNG image of the network

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Top targets:


Showing 1 to 20 of 89 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_14562171 0.810 ENSMUST00000181796.1
 Vmn1r90
vomeronasal 1 receptor 90
chr1_-_157256682 0.716 ENSMUST00000134543.1
 Rasal2
RAS protein activator like 2
chr18_+_37513652 0.629 ENSMUST00000061405.4
 Pcdhb21
protocadherin beta 21
chr4_-_14621805 0.624 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr1_-_126830786 0.611 ENSMUST00000162646.1
 Nckap5
NCK-associated protein 5
chr10_-_11080956 0.582 ENSMUST00000105560.1
 Grm1
glutamate receptor, metabotropic 1
chr13_+_16014457 0.560 ENSMUST00000164993.1
 Inhba
inhibin beta-A
chr10_+_67096456 0.549 ENSMUST00000174317.1
 Jmjd1c
jumonji domain containing 1C
chr12_-_101958148 0.512 ENSMUST00000159883.1
ENSMUST00000160251.1
ENSMUST00000161011.1
ENSMUST00000021606.5
 Atxn3



ataxin 3



chr6_+_13069758 0.500 ENSMUST00000124234.1
ENSMUST00000142211.1
ENSMUST00000031556.7
 Tmem106b


transmembrane protein 106B


chr4_-_82850721 0.495 ENSMUST00000139401.1
 Zdhhc21
zinc finger, DHHC domain containing 21
chr15_+_92597104 0.465 ENSMUST00000035399.8
 Pdzrn4
PDZ domain containing RING finger 4
chr4_+_115737738 0.451 ENSMUST00000106525.2
 Efcab14
EF-hand calcium binding domain 14
chr18_+_51117754 0.430 ENSMUST00000116639.2
 Prr16
proline rich 16
chrX_+_159697308 0.426 ENSMUST00000123433.1
 Sh3kbp1
SH3-domain kinase binding protein 1
chr16_+_43508118 0.410 ENSMUST00000114690.1
 Zbtb20
zinc finger and BTB domain containing 20
chr9_-_95750335 0.408 ENSMUST00000053785.3
 Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr2_-_45110336 0.407 ENSMUST00000028229.6
ENSMUST00000152232.1
 Zeb2

zinc finger E-box binding homeobox 2

chr9_+_14276301 0.402 ENSMUST00000034507.7
 Sesn3
sestrin 3
chrX_-_105929206 0.396 ENSMUST00000134381.1
ENSMUST00000154866.1
 Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0019532 oxalate transport(GO:0019532)
0.2 0.7 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.0 0.7 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.1 0.6 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.0 0.6 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.5 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 0.4 GO:2000224 testosterone biosynthetic process(GO:0061370) regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.4 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.4 GO:0030035 microspike assembly(GO:0030035)
0.0 0.4 GO:0046541 saliva secretion(GO:0046541)
0.0 0.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.3 GO:1901731 calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731)
0.1 0.3 GO:0006547 histidine metabolic process(GO:0006547)
0.0 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.7 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.1 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 0.6 GO:0043512 inhibin A complex(GO:0043512)
0.1 0.6 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.1 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)

Gene overrepresentation in molecular_function category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.7 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.6 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.5 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.1 0.4 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)