Motif ID: Foxd3

Z-value: 0.664


Transcription factors associated with Foxd3:

Gene SymbolEntrez IDGene Name
Foxd3 ENSMUSG00000067261.3 Foxd3



Activity profile for motif Foxd3.

activity profile for motif Foxd3


Sorted Z-values histogram for motif Foxd3

Sorted Z-values for motif Foxd3



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxd3

PNG image of the network

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Top targets:


Showing 1 to 20 of 60 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_144209471 3.243 ENSMUST00000038815.7
 Sox5
SRY-box containing gene 5
chr6_-_144209558 3.208 ENSMUST00000111749.1
ENSMUST00000170367.2
 Sox5

SRY-box containing gene 5

chrX_+_164373363 1.710 ENSMUST00000033751.7
 Figf
c-fos induced growth factor
chr14_-_70630149 1.413 ENSMUST00000022694.9
 Dmtn
dematin actin binding protein
chr6_+_77242644 1.347 ENSMUST00000159616.1
 Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr6_+_77242715 1.307 ENSMUST00000161677.1
 Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr4_-_82850721 1.291 ENSMUST00000139401.1
 Zdhhc21
zinc finger, DHHC domain containing 21
chr1_-_126830786 1.242 ENSMUST00000162646.1
 Nckap5
NCK-associated protein 5
chr13_+_16014457 1.237 ENSMUST00000164993.1
 Inhba
inhibin beta-A
chr1_-_126830632 1.109 ENSMUST00000112583.1
ENSMUST00000094609.3
 Nckap5

NCK-associated protein 5

chr11_+_98798653 1.078 ENSMUST00000037930.6
 Msl1
male-specific lethal 1 homolog (Drosophila)
chr15_+_92597104 1.049 ENSMUST00000035399.8
 Pdzrn4
PDZ domain containing RING finger 4
chr11_+_83302817 0.847 ENSMUST00000142680.1
 Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr15_+_100154379 0.797 ENSMUST00000023768.6
ENSMUST00000108971.2
 Dip2b

DIP2 disco-interacting protein 2 homolog B (Drosophila)

chr8_-_87959560 0.790 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr10_-_19011948 0.785 ENSMUST00000105527.1
 Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr2_-_45110336 0.749 ENSMUST00000028229.6
ENSMUST00000152232.1
 Zeb2

zinc finger E-box binding homeobox 2

chr5_+_148265202 0.728 ENSMUST00000110515.2
 Mtus2
microtubule associated tumor suppressor candidate 2
chr17_+_28691419 0.724 ENSMUST00000124886.1
 Mapk14
mitogen-activated protein kinase 14
chr5_-_88675190 0.717 ENSMUST00000133532.1
ENSMUST00000150438.1
 Grsf1

G-rich RNA sequence binding factor 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 6.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 2.7 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.5 1.4 GO:1901731 calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731)
0.1 1.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 1.2 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.2 1.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 1.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.3 0.8 GO:0070428 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.2 0.8 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.8 GO:0035904 aorta development(GO:0035904)
0.1 0.7 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.5 GO:0021814 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814)
0.1 0.4 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.4 GO:0006547 histidine metabolic process(GO:0006547)
0.0 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.4 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 0.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.5 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 3.0 GO:0030426 growth cone(GO:0030426)
0.0 1.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.4 1.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.4 1.2 GO:0043512 inhibin A complex(GO:0043512)
0.2 1.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.4 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.4 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.3 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 2.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 2.2 GO:0043621 protein self-association(GO:0043621)
0.1 1.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.2 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.8 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.8 GO:0030276 clathrin binding(GO:0030276)
0.0 0.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.6 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.4 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639)
0.1 0.4 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889) acetylcholine binding(GO:0042166)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)