Motif ID: Foxi1_Foxo1

Z-value: 1.548

Transcription factors associated with Foxi1_Foxo1:

Gene SymbolEntrez IDGene Name
Foxi1 ENSMUSG00000047861.2 Foxi1
Foxo1 ENSMUSG00000044167.5 Foxo1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxo1mm10_v2_chr3_+_52268337_522683880.244.0e-01Click!


Activity profile for motif Foxi1_Foxo1.

activity profile for motif Foxi1_Foxo1


Sorted Z-values histogram for motif Foxi1_Foxo1

Sorted Z-values for motif Foxi1_Foxo1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxi1_Foxo1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_20665250 9.541 ENSMUST00000075312.3
 Ttr
transthyretin
chrY_+_1010543 5.462 ENSMUST00000091197.3
 Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr15_+_3270767 4.911 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr8_-_46294592 4.459 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr4_+_94739276 3.891 ENSMUST00000073939.6
ENSMUST00000102798.1
 Tek

endothelial-specific receptor tyrosine kinase

chr1_-_171196229 3.260 ENSMUST00000111332.1
 Pcp4l1
Purkinje cell protein 4-like 1
chr13_+_65512678 2.856 ENSMUST00000081471.2
 Gm10139
predicted gene 10139
chr6_+_30541582 2.771 ENSMUST00000096066.4
 Cpa2
carboxypeptidase A2, pancreatic
chr8_+_116504973 2.746 ENSMUST00000078170.5
 Dynlrb2
dynein light chain roadblock-type 2
chr14_-_55560340 2.678 ENSMUST00000066106.3
 A730061H03Rik
RIKEN cDNA A730061H03 gene
chr4_+_144892813 2.647 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr3_+_118430299 2.585 ENSMUST00000180774.1
 Gm26871
predicted gene, 26871
chr4_-_143299498 2.491 ENSMUST00000030317.7
 Pdpn
podoplanin
chr3_+_34649987 2.424 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr14_-_51913393 2.332 ENSMUST00000004673.7
ENSMUST00000111632.3
 Ndrg2

N-myc downstream regulated gene 2

chrX_+_169685191 2.259 ENSMUST00000112104.1
ENSMUST00000112107.1
 Mid1

midline 1

chr7_-_79149042 2.226 ENSMUST00000032825.8
ENSMUST00000107409.3
 Mfge8

milk fat globule-EGF factor 8 protein

chr2_+_128126030 2.203 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
 Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr19_+_55741810 2.196 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
 Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr4_+_144893077 2.176 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 413 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 9.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.8 7.8 GO:0042572 retinol metabolic process(GO:0042572)
0.4 5.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.7 4.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 4.5 GO:0001967 suckling behavior(GO:0001967)
1.4 4.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.4 4.0 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.3 3.8 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 3.8 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.3 3.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 3.7 GO:0001893 maternal placenta development(GO:0001893)
0.4 3.6 GO:0021984 adenohypophysis development(GO:0021984)
0.8 3.0 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 2.8 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 2.7 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 2.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.8 2.4 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.8 2.4 GO:1901254 positive regulation of intracellular transport of viral material(GO:1901254)
0.6 2.4 GO:0042938 dipeptide transport(GO:0042938)
0.0 2.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 169 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.4 GO:0005615 extracellular space(GO:0005615)
0.0 11.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 9.0 GO:0031012 extracellular matrix(GO:0031012)
0.1 5.6 GO:0005902 microvillus(GO:0005902)
0.0 5.6 GO:0019866 organelle inner membrane(GO:0019866)
0.0 4.4 GO:0005813 centrosome(GO:0005813)
0.3 4.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.4 3.9 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.3 3.6 GO:0031931 TORC1 complex(GO:0031931)
0.0 3.4 GO:0000776 kinetochore(GO:0000776)
0.1 2.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 2.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.6 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.3 2.5 GO:0030478 actin cap(GO:0030478)
0.8 2.4 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.0 2.3 GO:0030175 filopodium(GO:0030175)
0.3 2.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.7 2.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 2.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 271 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.1 9.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.9 6.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.6 6.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.4 5.8 GO:0008430 selenium binding(GO:0008430)
0.1 4.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 4.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.3 3.7 GO:0015250 water channel activity(GO:0015250)
0.2 3.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 3.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.7 3.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 3.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 3.0 GO:0045502 dynein binding(GO:0045502)
0.1 2.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 2.9 GO:0003774 motor activity(GO:0003774)
0.3 2.8 GO:0050693 LBD domain binding(GO:0050693)
0.3 2.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.6 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.1 2.5 GO:0042287 MHC protein binding(GO:0042287)