Motif ID: Foxj3_Tbl1xr1

Z-value: 1.094

Transcription factors associated with Foxj3_Tbl1xr1:

Gene SymbolEntrez IDGene Name
Foxj3 ENSMUSG00000032998.10 Foxj3
Tbl1xr1 ENSMUSG00000027630.8 Tbl1xr1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxj3mm10_v2_chr4_+_119539652_1195396980.669.9e-03Click!
Tbl1xr1mm10_v2_chr3_+_22076644_220766810.461.0e-01Click!


Activity profile for motif Foxj3_Tbl1xr1.

activity profile for motif Foxj3_Tbl1xr1


Sorted Z-values histogram for motif Foxj3_Tbl1xr1

Sorted Z-values for motif Foxj3_Tbl1xr1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxj3_Tbl1xr1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_66860458 2.718 ENSMUST00000057942.2
 Mc4r
melanocortin 4 receptor
chr13_+_109260481 2.102 ENSMUST00000153234.1
 Pde4d
phosphodiesterase 4D, cAMP specific
chr1_-_126492900 2.036 ENSMUST00000161954.1
 Nckap5
NCK-associated protein 5
chr18_+_86711520 1.967 ENSMUST00000122464.1
 Cbln2
cerebellin 2 precursor protein
chr7_+_123982799 1.942 ENSMUST00000106437.1
 Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr9_+_34904913 1.886 ENSMUST00000045091.6
 Kirrel3
kin of IRRE like 3 (Drosophila)
chr11_-_110095937 1.883 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
 Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr1_-_154725920 1.870 ENSMUST00000004214.8
 Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr1_+_153740344 1.815 ENSMUST00000027748.7
 Rgs16
regulator of G-protein signaling 16
chr4_+_85205120 1.807 ENSMUST00000107188.3
 Sh3gl2
SH3-domain GRB2-like 2
chr18_-_13972617 1.757 ENSMUST00000025288.7
 Zfp521
zinc finger protein 521
chr10_+_100015817 1.739 ENSMUST00000130190.1
ENSMUST00000020129.7
 Kitl

kit ligand

chr2_-_64975762 1.719 ENSMUST00000156765.1
 Grb14
growth factor receptor bound protein 14
chr2_-_57113053 1.701 ENSMUST00000112627.1
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr11_-_110095974 1.676 ENSMUST00000100287.2
 Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr16_-_22161450 1.648 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr6_+_51432663 1.623 ENSMUST00000005103.5
 Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr1_-_158814469 1.614 ENSMUST00000161589.2
 Pappa2
pappalysin 2
chrX_+_164373363 1.613 ENSMUST00000033751.7
 Figf
c-fos induced growth factor
chr6_-_99028874 1.594 ENSMUST00000154163.2
 Foxp1
forkhead box P1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 809 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 7.7 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 6.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.7 5.4 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.3 4.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.5 3.7 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.3 3.7 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 3.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.5 3.2 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.2 3.2 GO:0060013 righting reflex(GO:0060013)
0.0 3.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.6 3.1 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.5 3.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 2.9 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 2.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.7 2.7 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 2.7 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 2.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 2.6 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 2.4 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.5 2.3 GO:0042636 negative regulation of hair cycle(GO:0042636) negative regulation of hair follicle development(GO:0051799)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 295 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 10.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 7.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 6.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 5.7 GO:0043198 dendritic shaft(GO:0043198)
0.1 5.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.1 GO:0036064 ciliary basal body(GO:0036064)
0.1 2.9 GO:0071565 nBAF complex(GO:0071565)
0.0 2.9 GO:0005643 nuclear pore(GO:0005643)
0.1 2.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 2.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 2.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.6 2.3 GO:0031673 H zone(GO:0031673)
0.0 2.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.3 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 2.0 GO:0097470 ribbon synapse(GO:0097470)
0.1 2.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 1.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 1.9 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.8 GO:0031045 dense core granule(GO:0031045)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 484 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 9.4 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 6.7 GO:0003779 actin binding(GO:0003779)
0.2 5.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 5.0 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.0 5.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 4.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 4.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 4.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 3.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 3.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 3.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 3.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 3.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 3.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2 3.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 2.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.9 2.7 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.4 2.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 2.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.6 GO:0004027 alcohol sulfotransferase activity(GO:0004027)