Motif ID: Foxk1_Foxj1

Z-value: 0.556

Transcription factors associated with Foxk1_Foxj1:

Gene SymbolEntrez IDGene Name
Foxj1 ENSMUSG00000034227.7 Foxj1
Foxk1 ENSMUSG00000056493.8 Foxk1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxk1mm10_v2_chr5_+_142401484_142401532-0.806.4e-04Click!
Foxj1mm10_v2_chr11_-_116335384_1163353990.714.1e-03Click!


Activity profile for motif Foxk1_Foxj1.

activity profile for motif Foxk1_Foxj1


Sorted Z-values histogram for motif Foxk1_Foxj1

Sorted Z-values for motif Foxk1_Foxj1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxk1_Foxj1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_140968028 1.406 ENSMUST00000106040.1
ENSMUST00000026564.8
 Ifitm1

interferon induced transmembrane protein 1

chr10_+_97482350 1.110 ENSMUST00000163448.2
 Dcn
decorin
chrX_+_170010744 1.088 ENSMUST00000178789.1
 Gm21887
predicted gene, 21887
chr13_-_103920295 1.052 ENSMUST00000169083.1
 Erbb2ip
Erbb2 interacting protein
chrY_+_90785442 0.953 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
 Erdr1


erythroid differentiation regulator 1


chr4_+_94739276 0.896 ENSMUST00000073939.6
ENSMUST00000102798.1
 Tek

endothelial-specific receptor tyrosine kinase

chr15_-_75048837 0.820 ENSMUST00000179762.1
ENSMUST00000065408.9
 Ly6c1

lymphocyte antigen 6 complex, locus C1

chr4_-_55532453 0.757 ENSMUST00000132746.1
ENSMUST00000107619.2
 Klf4

Kruppel-like factor 4 (gut)

chr1_+_45311538 0.721 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr3_+_159495408 0.687 ENSMUST00000120272.1
ENSMUST00000029825.7
ENSMUST00000106041.2
 Depdc1a


DEP domain containing 1a


chrY_+_1010543 0.663 ENSMUST00000091197.3
 Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr1_-_97977233 0.653 ENSMUST00000161567.1
 Pam
peptidylglycine alpha-amidating monooxygenase
chr12_-_103443653 0.638 ENSMUST00000055071.8
 Ifi27l2a
interferon, alpha-inducible protein 27 like 2A
chr6_-_48708206 0.630 ENSMUST00000119315.1
ENSMUST00000053661.4
 Gimap6

GTPase, IMAP family member 6

chr1_-_144177259 0.629 ENSMUST00000111941.1
ENSMUST00000052375.1
 Rgs13

regulator of G-protein signaling 13

chr16_+_42907563 0.593 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chrX_+_7722267 0.585 ENSMUST00000125991.1
ENSMUST00000148624.1
 Wdr45

WD repeat domain 45

chr15_+_57912199 0.584 ENSMUST00000022992.6
 Tbc1d31
TBC1 domain family, member 31
chr19_+_3935186 0.574 ENSMUST00000162708.1
ENSMUST00000165711.1
 Unc93b1

unc-93 homolog B1 (C. elegans)

chrX_+_7722214 0.553 ENSMUST00000043045.2
ENSMUST00000116634.1
ENSMUST00000115689.3
ENSMUST00000131077.1
ENSMUST00000115688.1
ENSMUST00000116633.1
 Wdr45





WD repeat domain 45






Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 108 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 1.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 1.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.3 1.1 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.2 1.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 1.0 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.2 0.9 GO:0042938 dipeptide transport(GO:0042938)
0.3 0.8 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.0 0.8 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.8 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.1 0.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.7 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.7 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.2 0.6 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.6 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.2 0.5 GO:0009812 flavonoid metabolic process(GO:0009812) flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696)
0.2 0.5 GO:0036292 positive regulation of prostaglandin biosynthetic process(GO:0031394) DNA rewinding(GO:0036292) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2 0.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 1.6 GO:0070469 respiratory chain(GO:0070469)
0.0 1.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.7 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.6 GO:0032009 early phagosome(GO:0032009)
0.1 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.5 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.3 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.3 GO:0097227 sperm annulus(GO:0097227)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0044327 dendritic spine membrane(GO:0032591) dendritic spine head(GO:0044327)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 1.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 0.9 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 0.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.8 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 0.7 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.6 GO:0035325 Toll-like receptor binding(GO:0035325)
0.1 0.5 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.3 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.3 GO:0030284 estrogen receptor activity(GO:0030284)