Motif ID: Foxl1

Z-value: 1.081


Transcription factors associated with Foxl1:

Gene SymbolEntrez IDGene Name
Foxl1 ENSMUSG00000097084.1 Foxl1
Foxl1 ENSMUSG00000043867.5 Foxl1



Activity profile for motif Foxl1.

activity profile for motif Foxl1


Sorted Z-values histogram for motif Foxl1

Sorted Z-values for motif Foxl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxl1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_102490418 8.573 ENSMUST00000020040.3
 Nts
neurotensin
chr7_+_122289297 3.658 ENSMUST00000064989.5
ENSMUST00000064921.4
 Prkcb

protein kinase C, beta

chr13_-_23622502 3.259 ENSMUST00000062045.2
 Hist1h1e
histone cluster 1, H1e
chr6_-_147264124 2.537 ENSMUST00000052296.6
 Pthlh
parathyroid hormone-like peptide
chr13_+_23763660 2.499 ENSMUST00000055770.1
 Hist1h1a
histone cluster 1, H1a
chr16_+_43508118 1.768 ENSMUST00000114690.1
 Zbtb20
zinc finger and BTB domain containing 20
chr2_+_119325784 1.714 ENSMUST00000102517.3
 Dll4
delta-like 4 (Drosophila)
chr9_+_71215779 1.595 ENSMUST00000034723.5
 Aldh1a2
aldehyde dehydrogenase family 1, subfamily A2
chr16_+_45093611 1.529 ENSMUST00000099498.2
 Ccdc80
coiled-coil domain containing 80
chrM_+_2743 1.226 ENSMUST00000082392.1
 mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr7_+_91090728 1.214 ENSMUST00000074273.3
 Dlg2
discs, large homolog 2 (Drosophila)
chr4_+_11191726 1.157 ENSMUST00000029866.9
ENSMUST00000108324.3
 Ccne2

cyclin E2

chr2_-_59948155 1.146 ENSMUST00000153136.1
 Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr7_+_91090697 1.131 ENSMUST00000107196.2
 Dlg2
discs, large homolog 2 (Drosophila)
chr17_-_91092715 1.126 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
 Nrxn1


neurexin I


chr13_+_23555023 1.021 ENSMUST00000045301.6
 Hist1h1d
histone cluster 1, H1d
chr18_-_15151427 0.925 ENSMUST00000025992.6
 Kctd1
potassium channel tetramerisation domain containing 1
chr16_-_22439570 0.867 ENSMUST00000170393.1
 Etv5
ets variant gene 5
chr2_-_147186389 0.808 ENSMUST00000109970.3
ENSMUST00000067075.5
 Nkx2-2

NK2 homeobox 2

chr17_+_40811089 0.718 ENSMUST00000024721.7
 Rhag
Rhesus blood group-associated A glycoprotein
chrX_+_18162575 0.617 ENSMUST00000044484.6
ENSMUST00000052368.8
 Kdm6a

lysine (K)-specific demethylase 6A

chrX_+_112604274 0.609 ENSMUST00000071814.6
 Zfp711
zinc finger protein 711
chr9_-_101198999 0.603 ENSMUST00000066773.7
 Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr18_+_34409415 0.549 ENSMUST00000166156.1
ENSMUST00000014647.7
 Pkd2l2

polycystic kidney disease 2-like 2

chr18_-_25753852 0.495 ENSMUST00000025117.6
ENSMUST00000115816.2
 Celf4

CUGBP, Elav-like family member 4

chr15_+_43477213 0.479 ENSMUST00000022962.6
 Emc2
ER membrane protein complex subunit 2
chr6_+_42286676 0.438 ENSMUST00000031894.6
 Clcn1
chloride channel 1
chr16_+_30065333 0.413 ENSMUST00000023171.7
 Hes1
hairy and enhancer of split 1 (Drosophila)
chr9_+_44069421 0.348 ENSMUST00000114830.2
 Usp2
ubiquitin specific peptidase 2
chr13_+_23575753 0.287 ENSMUST00000105105.1
 Hist1h3d
histone cluster 1, H3d
chrX_-_94123087 0.222 ENSMUST00000113925.1
 Zfx
zinc finger protein X-linked
chr2_+_91255954 0.174 ENSMUST00000134699.1
 Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr2_+_18055203 0.091 ENSMUST00000028076.8
 Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr2_+_91256144 0.049 ENSMUST00000154959.1
ENSMUST00000059566.4
 Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr1_-_170110491 0.027 ENSMUST00000027985.2
 Ddr2
discoidin domain receptor family, member 2
chr10_+_56377300 0.006 ENSMUST00000068581.7
 Gja1
gap junction protein, alpha 1
chr2_-_94264713 0.003 ENSMUST00000129661.1
 E530001K10Rik
RIKEN cDNA E530001K10 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.7 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.6 4.2 GO:0016584 nucleosome positioning(GO:0016584)
0.6 1.7 GO:0072554 blood vessel lumenization(GO:0072554)
0.5 1.6 GO:0035799 ureter maturation(GO:0035799)
0.4 2.5 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.3 0.8 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 1.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.2 0.6 GO:0007525 somatic muscle development(GO:0007525)
0.2 0.9 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 2.3 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.1 0.7 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.4 GO:0021557 oculomotor nerve development(GO:0021557) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 8.6 GO:0008542 visual learning(GO:0008542)
0.1 0.5 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.2 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 1.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 1.2 GO:0006270 DNA replication initiation(GO:0006270)
0.0 2.8 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.2 GO:0060746 parental behavior(GO:0060746)
0.0 0.5 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 1.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 7.0 GO:0000786 nucleosome(GO:0000786)
0.1 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 3.7 GO:0031526 brush border membrane(GO:0031526)
0.0 8.6 GO:0043679 axon terminus(GO:0043679)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.2 GO:0070469 respiratory chain(GO:0070469)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.7 GO:0035184 histone threonine kinase activity(GO:0035184)
0.4 8.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.3 1.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.3 1.6 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 2.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 2.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 1.7 GO:0005112 Notch binding(GO:0005112)
0.1 1.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 1.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.0 GO:0031490 chromatin DNA binding(GO:0031490)