Motif ID: Foxm1

Z-value: 0.937


Transcription factors associated with Foxm1:

Gene SymbolEntrez IDGene Name
Foxm1 ENSMUSG00000001517.8 Foxm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxm1mm10_v2_chr6_+_128362919_128363058-0.582.8e-02Click!


Activity profile for motif Foxm1.

activity profile for motif Foxm1


Sorted Z-values histogram for motif Foxm1

Sorted Z-values for motif Foxm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxm1

PNG image of the network

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Top targets:


Showing 1 to 20 of 125 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_164373363 4.288 ENSMUST00000033751.7
Figf
c-fos induced growth factor
chr19_+_25672408 3.523 ENSMUST00000053068.5
Dmrt2
doublesex and mab-3 related transcription factor 2
chr2_+_65845833 2.672 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr6_-_59024340 2.611 ENSMUST00000173193.1
Fam13a
family with sequence similarity 13, member A
chr10_-_130280218 2.580 ENSMUST00000061571.3
Neurod4
neurogenic differentiation 4
chr4_-_15149755 2.294 ENSMUST00000108273.1
Necab1
N-terminal EF-hand calcium binding protein 1
chr2_+_96318014 1.833 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr8_-_36732897 1.650 ENSMUST00000098826.3
Dlc1
deleted in liver cancer 1
chr10_-_63927434 1.611 ENSMUST00000079279.3
Gm10118
predicted gene 10118
chr14_-_24486994 1.528 ENSMUST00000026322.7
Polr3a
polymerase (RNA) III (DNA directed) polypeptide A
chr18_+_67133713 1.475 ENSMUST00000076605.7
Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr9_-_75597643 1.320 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr11_+_94044111 1.228 ENSMUST00000132079.1
Spag9
sperm associated antigen 9
chr10_+_11281583 1.176 ENSMUST00000070300.4
Fbxo30
F-box protein 30
chr2_+_68117713 1.084 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr18_-_62741387 1.071 ENSMUST00000097557.3
Spink13
serine peptidase inhibitor, Kazal type 13
chr12_-_51971289 0.975 ENSMUST00000040583.5
Heatr5a
HEAT repeat containing 5A
chr13_+_55209776 0.969 ENSMUST00000099490.2
Nsd1
nuclear receptor-binding SET-domain protein 1
chr12_-_99393010 0.938 ENSMUST00000177451.1
Foxn3
forkhead box N3
chr19_-_40402267 0.925 ENSMUST00000099467.3
ENSMUST00000099466.3
ENSMUST00000165212.1
ENSMUST00000165469.1
Sorbs1



sorbin and SH3 domain containing 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 3.5 GO:0061055 myotome development(GO:0061055)
0.0 3.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.3 2.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 2.0 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 1.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 1.7 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 1.5 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 1.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 1.4 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 1.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 1.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 1.1 GO:0060467 negative regulation of fertilization(GO:0060467)
0.1 1.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.0 GO:1903025 regulation of histone H3-K36 methylation(GO:0000414) regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.9 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.9 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.2 0.8 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.8 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.2 0.7 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.7 GO:0007029 endoplasmic reticulum organization(GO:0007029)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.4 GO:0097470 ribbon synapse(GO:0097470)
0.1 1.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.0 GO:0035097 histone methyltransferase complex(GO:0035097)
0.3 0.9 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.8 GO:0031045 dense core granule(GO:0031045)
0.0 0.7 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 0.6 GO:0002177 manchette(GO:0002177)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.3 GO:0001652 granular component(GO:0001652)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.3 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.2 2.0 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 1.9 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 1.8 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.5 1.5 GO:0050827 toxin receptor binding(GO:0050827)
0.1 1.5 GO:0017166 vinculin binding(GO:0017166)
0.1 1.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 1.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 1.3 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.8 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.7 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.7 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.6 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.2 0.5 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)