Motif ID: Foxn1

Z-value: 0.632


Transcription factors associated with Foxn1:

Gene SymbolEntrez IDGene Name
Foxn1 ENSMUSG00000002057.4 Foxn1



Activity profile for motif Foxn1.

activity profile for motif Foxn1


Sorted Z-values histogram for motif Foxn1

Sorted Z-values for motif Foxn1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxn1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_123982799 3.146 ENSMUST00000106437.1
 Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr11_+_67455339 0.976 ENSMUST00000108681.1
 Gas7
growth arrest specific 7
chrX_+_151803642 0.885 ENSMUST00000156616.2
 Huwe1
HECT, UBA and WWE domain containing 1
chr1_-_155099630 0.860 ENSMUST00000055322.4
 Ier5
immediate early response 5
chr5_+_21424934 0.817 ENSMUST00000056045.4
 Fam185a
family with sequence similarity 185, member A
chr14_+_111675113 0.780 ENSMUST00000042767.7
 Slitrk5
SLIT and NTRK-like family, member 5
chr9_-_72985344 0.768 ENSMUST00000124565.2
 Gm5918
predicted gene 5918
chr8_-_111876661 0.757 ENSMUST00000034431.1
 Tmem170
transmembrane protein 170
chr13_+_77135513 0.647 ENSMUST00000168779.1
 2210408I21Rik
RIKEN cDNA 2210408I21 gene
chr10_+_19934472 0.617 ENSMUST00000095806.3
ENSMUST00000120259.1
 Map3k5

mitogen-activated protein kinase kinase kinase 5

chr3_-_158562199 0.573 ENSMUST00000106044.1
 Lrrc7
leucine rich repeat containing 7
chr11_+_30771726 0.566 ENSMUST00000041231.7
 Psme4
proteasome (prosome, macropain) activator subunit 4
chr19_+_46152505 0.560 ENSMUST00000026254.7
 Gbf1
golgi-specific brefeldin A-resistance factor 1
chr9_-_95750335 0.548 ENSMUST00000053785.3
 Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr10_+_88379127 0.489 ENSMUST00000127615.1
 Gnptab
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr17_+_6106464 0.480 ENSMUST00000142030.1
 Tulp4
tubby like protein 4
chr18_+_32938955 0.453 ENSMUST00000042868.4
 Camk4
calcium/calmodulin-dependent protein kinase IV
chr9_-_45984816 0.434 ENSMUST00000172450.1
 Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr7_+_100372224 0.425 ENSMUST00000051777.8
ENSMUST00000098259.4
 C2cd3

C2 calcium-dependent domain containing 3

chr14_-_57746044 0.409 ENSMUST00000173990.1
ENSMUST00000022531.7
 Lats2

large tumor suppressor 2

chrX_+_151803313 0.408 ENSMUST00000026292.8
 Huwe1
HECT, UBA and WWE domain containing 1
chr13_-_64274879 0.394 ENSMUST00000109770.1
 Cdc14b
CDC14 cell division cycle 14B
chr6_-_30896735 0.371 ENSMUST00000048774.6
ENSMUST00000166192.1
ENSMUST00000135230.1
 Copg2


coatomer protein complex, subunit gamma 2


chr11_-_104550392 0.366 ENSMUST00000106962.2
 Cdc27
cell division cycle 27
chr14_+_63606491 0.345 ENSMUST00000119973.2
 Xkr6
X Kell blood group precursor related family member 6 homolog
chrX_-_74085656 0.324 ENSMUST00000033770.6
 Mecp2
methyl CpG binding protein 2
chr19_+_36834215 0.324 ENSMUST00000025729.5
 Tnks2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr7_-_81829431 0.321 ENSMUST00000026093.7
 Btbd1
BTB (POZ) domain containing 1
chr9_-_64737623 0.294 ENSMUST00000169058.1
 Rab11a
RAB11a, member RAS oncogene family
chr18_-_46525940 0.274 ENSMUST00000036226.5
 Fem1c
fem-1 homolog c (C.elegans)
chr2_+_32395896 0.270 ENSMUST00000028162.3
 Ptges2
prostaglandin E synthase 2
chr17_-_80062333 0.265 ENSMUST00000061331.7
 Hnrnpll
heterogeneous nuclear ribonucleoprotein L-like
chr8_-_94012120 0.259 ENSMUST00000143265.1
 Amfr
autocrine motility factor receptor
chr11_-_104550460 0.253 ENSMUST00000106961.1
ENSMUST00000093923.2
 Cdc27

cell division cycle 27

chr1_-_178337774 0.249 ENSMUST00000037748.7
 Hnrnpu
heterogeneous nuclear ribonucleoprotein U
chr6_-_32588192 0.248 ENSMUST00000115096.2
 Plxna4
plexin A4
chr11_-_69758630 0.243 ENSMUST00000058470.9
 Polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr11_+_93996082 0.242 ENSMUST00000041956.7
 Spag9
sperm associated antigen 9
chr9_-_64737684 0.241 ENSMUST00000171100.1
ENSMUST00000167569.1
ENSMUST00000004892.6
ENSMUST00000172298.1
 Rab11a



RAB11a, member RAS oncogene family



chr9_+_72985504 0.235 ENSMUST00000156879.1
 Ccpg1
cell cycle progression 1
chr10_+_88379217 0.233 ENSMUST00000130301.1
ENSMUST00000020251.8
 Gnptab

N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits

chr14_+_75284343 0.232 ENSMUST00000022577.5
 Zc3h13
zinc finger CCCH type containing 13
chr6_+_28480337 0.228 ENSMUST00000001460.7
ENSMUST00000167201.1
 Snd1

staphylococcal nuclease and tudor domain containing 1

chr4_+_40722461 0.225 ENSMUST00000030118.3
 Dnaja1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr11_-_69758223 0.218 ENSMUST00000071213.3
 Polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr3_+_152210458 0.211 ENSMUST00000166984.1
ENSMUST00000106121.1
 Fubp1

far upstream element (FUSE) binding protein 1

chr14_-_99099701 0.196 ENSMUST00000042471.9
 Dis3
DIS3 mitotic control homolog (S. cerevisiae)
chr9_+_69989466 0.190 ENSMUST00000034754.5
ENSMUST00000085393.6
ENSMUST00000117450.1
 Bnip2


BCL2/adenovirus E1B interacting protein 2


chr1_+_59119822 0.189 ENSMUST00000180570.1
 G730003C15Rik
RIKEN cDNA G730003C15 gene
chrX_-_111463103 0.187 ENSMUST00000137712.2
 Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr9_+_72985410 0.180 ENSMUST00000037977.8
 Ccpg1
cell cycle progression 1
chr11_-_120348475 0.175 ENSMUST00000062147.7
ENSMUST00000128055.1
 Actg1

actin, gamma, cytoplasmic 1

chr12_-_105685235 0.174 ENSMUST00000041055.7
 Atg2b
autophagy related 2B
chr4_+_40722912 0.171 ENSMUST00000164233.1
ENSMUST00000137246.1
ENSMUST00000125442.1
 Dnaja1


DnaJ (Hsp40) homolog, subfamily A, member 1


chr9_+_21592722 0.167 ENSMUST00000062125.10
 1810026J23Rik
RIKEN cDNA 1810026J23 gene
chr6_+_149408973 0.165 ENSMUST00000086829.4
ENSMUST00000111513.2
 Bicd1

bicaudal D homolog 1 (Drosophila)

chr1_-_161876656 0.165 ENSMUST00000048377.5
 Suco
SUN domain containing ossification factor
chr9_-_119578981 0.157 ENSMUST00000117911.1
ENSMUST00000120420.1
 Scn5a

sodium channel, voltage-gated, type V, alpha

chrX_-_74085586 0.155 ENSMUST00000123362.1
ENSMUST00000140399.1
ENSMUST00000100750.3
 Mecp2


methyl CpG binding protein 2


chr7_+_133776857 0.150 ENSMUST00000065359.5
ENSMUST00000151031.1
ENSMUST00000121560.1
 Fank1


fibronectin type 3 and ankyrin repeat domains 1


chr11_+_97362396 0.145 ENSMUST00000045540.3
 Socs7
suppressor of cytokine signaling 7
chr16_-_96082513 0.141 ENSMUST00000113827.1
 Brwd1
bromodomain and WD repeat domain containing 1
chr17_-_80062199 0.137 ENSMUST00000184635.1
 Hnrnpll
heterogeneous nuclear ribonucleoprotein L-like
chr9_+_72985568 0.132 ENSMUST00000150826.2
ENSMUST00000085350.4
ENSMUST00000140675.1
 Ccpg1


cell cycle progression 1


chr9_+_70207342 0.126 ENSMUST00000034745.7
 Myo1e
myosin IE
chr7_-_133776772 0.126 ENSMUST00000033290.5
 Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr19_+_43612299 0.124 ENSMUST00000057178.9
 Nkx2-3
NK2 homeobox 3
chrX_+_101429555 0.123 ENSMUST00000033673.6
 Nono
non-POU-domain-containing, octamer binding protein
chrX_+_99136119 0.119 ENSMUST00000052839.6
 Efnb1
ephrin B1
chr3_-_116007399 0.116 ENSMUST00000067485.3
 Slc30a7
solute carrier family 30 (zinc transporter), member 7
chr8_-_11008458 0.116 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2
chr7_-_133776681 0.110 ENSMUST00000130182.1
ENSMUST00000106139.1
 Dhx32

DEAH (Asp-Glu-Ala-His) box polypeptide 32

chr11_-_97744659 0.110 ENSMUST00000018691.8
 Pip4k2b
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr4_-_121215071 0.107 ENSMUST00000056635.5
 Rlf
rearranged L-myc fusion sequence
chr13_-_64274962 0.098 ENSMUST00000039318.8
 Cdc14b
CDC14 cell division cycle 14B
chr7_-_100371889 0.097 ENSMUST00000032963.8
 Ppme1
protein phosphatase methylesterase 1
chr18_+_60526194 0.092 ENSMUST00000025505.5
 Dctn4
dynactin 4
chr5_+_130171798 0.085 ENSMUST00000119797.1
ENSMUST00000148264.1
 Rabgef1

RAB guanine nucleotide exchange factor (GEF) 1

chr18_-_37935378 0.077 ENSMUST00000025337.7
 Diap1
diaphanous homolog 1 (Drosophila)
chr7_-_25297866 0.074 ENSMUST00000148150.1
ENSMUST00000155118.1
 Pafah1b3

platelet-activating factor acetylhydrolase, isoform 1b, subunit 3

chr9_-_75683992 0.057 ENSMUST00000034699.6
 Scg3
secretogranin III
chr2_-_163645125 0.056 ENSMUST00000017851.3
 Serinc3
serine incorporator 3
chr4_+_122836236 0.051 ENSMUST00000030412.4
ENSMUST00000121870.1
ENSMUST00000097902.4
 Ppt1


palmitoyl-protein thioesterase 1


chr6_+_113442569 0.048 ENSMUST00000101070.4
 Jagn1
jagunal homolog 1 (Drosophila)
chr7_+_127588698 0.048 ENSMUST00000033088.6
 Rnf40
ring finger protein 40
chr8_+_105636509 0.042 ENSMUST00000005841.9
 Ctcf
CCCTC-binding factor
chr17_+_47688992 0.041 ENSMUST00000156118.1
 Frs3
fibroblast growth factor receptor substrate 3
chr8_-_83332416 0.041 ENSMUST00000177594.1
ENSMUST00000053902.3
 Elmod2

ELMO/CED-12 domain containing 2

chrX_-_74249819 0.038 ENSMUST00000114299.1
 Flna
filamin, alpha
chr5_-_115300957 0.034 ENSMUST00000009157.3
 Dynll1
dynein light chain LC8-type 1
chr17_-_57031468 0.033 ENSMUST00000007814.8
 Khsrp
KH-type splicing regulatory protein
chr9_-_21592805 0.023 ENSMUST00000034700.7
ENSMUST00000180365.1
ENSMUST00000078572.7
 Yipf2


Yip1 domain family, member 2


chr7_-_25297967 0.015 ENSMUST00000005583.5
 Pafah1b3
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr17_-_36951636 0.014 ENSMUST00000040402.7
ENSMUST00000174711.1
 Ppp1r11

protein phosphatase 1, regulatory (inhibitor) subunit 11

chr6_-_85374606 0.012 ENSMUST00000060837.7
 Rab11fip5
RAB11 family interacting protein 5 (class I)
chr6_+_38433913 0.008 ENSMUST00000160583.1
 Ubn2
ubinuclein 2
chr6_-_39725448 0.007 ENSMUST00000002487.8
 Braf
Braf transforming gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.2 0.6 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 0.5 GO:0009405 pathogenesis(GO:0009405)
0.1 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.4 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.1 0.5 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.1 0.4 GO:0061511 centriole elongation(GO:0061511)
0.1 0.2 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.1 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.2 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.1 0.6 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.1 0.2 GO:1900275 negative regulation of phospholipase C activity(GO:1900275) regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.1 0.5 GO:0046541 saliva secretion(GO:0046541)
0.1 0.5 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.8 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 0.2 GO:0086017 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) Purkinje myocyte action potential(GO:0086017) membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.4 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.2 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.8 GO:0021756 striatum development(GO:0021756)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 1.3 GO:0006284 base-excision repair(GO:0006284)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.5 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166) glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.3 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.5 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.2 GO:0044804 nucleophagy(GO:0044804)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.6 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788) cis-Golgi network(GO:0005801)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 0.5 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.5 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 3.1 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.1 0.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.4 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.5 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)