Motif ID: Foxo6

Z-value: 0.646


Transcription factors associated with Foxo6:

Gene SymbolEntrez IDGene Name
Foxo6 ENSMUSG00000052135.8 Foxo6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxo6mm10_v2_chr4_-_120287349_1202873490.641.4e-02Click!


Activity profile for motif Foxo6.

activity profile for motif Foxo6


Sorted Z-values histogram for motif Foxo6

Sorted Z-values for motif Foxo6



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxo6

PNG image of the network

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Top targets:


Showing 1 to 20 of 91 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_88724667 1.279 ENSMUST00000163271.1
 Mgll
monoglyceride lipase
chr1_-_184883218 1.013 ENSMUST00000048308.5
 C130074G19Rik
RIKEN cDNA C130074G19 gene
chr11_+_29463735 0.771 ENSMUST00000155854.1
 Ccdc88a
coiled coil domain containing 88A
chr4_+_102570065 0.727 ENSMUST00000097950.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr8_+_25911670 0.721 ENSMUST00000120653.1
ENSMUST00000126226.1
 Kcnu1

potassium channel, subfamily U, member 1

chr11_-_12027958 0.645 ENSMUST00000109654.1
 Grb10
growth factor receptor bound protein 10
chr10_-_93310963 0.609 ENSMUST00000151153.1
 Elk3
ELK3, member of ETS oncogene family
chr6_-_23248264 0.550 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chrX_-_163761323 0.515 ENSMUST00000059320.2
 Rnf138rt1
ring finger protein 138, retrogene 1
chr8_+_46986913 0.436 ENSMUST00000039840.7
ENSMUST00000119686.1
 Enpp6

ectonucleotide pyrophosphatase/phosphodiesterase 6

chr19_-_45742873 0.407 ENSMUST00000026241.5
ENSMUST00000026240.7
ENSMUST00000111928.1
 Fgf8


fibroblast growth factor 8


chr7_+_62476306 0.392 ENSMUST00000097132.3
 Atp5l-ps1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g, pseudogene 1
chr11_+_87853207 0.370 ENSMUST00000038196.6
 Mks1
Meckel syndrome, type 1
chr3_+_103968110 0.363 ENSMUST00000117150.1
ENSMUST00000063717.7
ENSMUST00000055425.8
ENSMUST00000123611.1
ENSMUST00000090685.4
 Phtf1




putative homeodomain transcription factor 1




chr10_-_93311073 0.351 ENSMUST00000008542.5
 Elk3
ELK3, member of ETS oncogene family
chrX_+_106920618 0.314 ENSMUST00000060576.7
 Lpar4
lysophosphatidic acid receptor 4
chr12_-_98577940 0.310 ENSMUST00000110113.1
 Kcnk10
potassium channel, subfamily K, member 10
chr1_+_74391479 0.300 ENSMUST00000027367.7
 Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr9_-_22071345 0.292 ENSMUST00000179605.1
ENSMUST00000043922.6
 Zfp653

zinc finger protein 653

chr1_+_171270321 0.280 ENSMUST00000064272.3
ENSMUST00000141999.1
ENSMUST00000111313.3
 B4galt3


UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.8 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.1 0.7 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.6 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.4 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.4 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.4 GO:1903887 motile primary cilium assembly(GO:1903887)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574) negative regulation of phagocytosis(GO:0050765)
0.1 0.2 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.2 GO:0097421 liver regeneration(GO:0097421)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0043196 varicosity(GO:0043196)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.1 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 1.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.8 GO:0043422 protein kinase B binding(GO:0043422)
0.2 0.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.7 GO:0030552 cAMP binding(GO:0030552)
0.0 0.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)