Motif ID: Foxp1_Foxj2

Z-value: 1.137

Transcription factors associated with Foxp1_Foxj2:

Gene SymbolEntrez IDGene Name
Foxj2 ENSMUSG00000003154.9 Foxj2
Foxp1 ENSMUSG00000030067.11 Foxp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxp1mm10_v2_chr6_-_99028251_990283130.761.7e-03Click!
Foxj2mm10_v2_chr6_+_122819888_1228199380.253.9e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Foxp1_Foxj2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_47333311 3.943 ENSMUST00000126684.1
ENSMUST00000156422.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr4_+_32238950 3.211 ENSMUST00000037416.6
Bach2
BTB and CNC homology 2
chr16_-_22161450 3.031 ENSMUST00000115379.1
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr15_-_60824942 2.937 ENSMUST00000100635.3
Fam84b
family with sequence similarity 84, member B
chr2_-_118256929 2.916 ENSMUST00000028820.6
ENSMUST00000028821.3
Fsip1

fibrous sheath-interacting protein 1

chr1_+_66386968 2.861 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr6_-_143947092 2.698 ENSMUST00000144289.1
ENSMUST00000111748.1
Sox5

SRY-box containing gene 5

chr11_-_107348130 2.659 ENSMUST00000134763.1
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr2_-_104712122 2.566 ENSMUST00000111118.1
ENSMUST00000028597.3
Tcp11l1

t-complex 11 like 1

chr16_-_34263179 2.559 ENSMUST00000114949.1
ENSMUST00000114954.1
Kalrn

kalirin, RhoGEF kinase

chr6_+_14901440 2.554 ENSMUST00000128567.1
Foxp2
forkhead box P2
chr6_-_148444336 2.446 ENSMUST00000060095.8
ENSMUST00000100772.3
Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr8_+_36457548 2.390 ENSMUST00000135373.1
ENSMUST00000147525.1
6430573F11Rik

RIKEN cDNA 6430573F11 gene

chr16_-_34262945 2.361 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr6_-_39725193 2.346 ENSMUST00000101497.3
Braf
Braf transforming gene
chr4_-_15149755 2.320 ENSMUST00000108273.1
Necab1
N-terminal EF-hand calcium binding protein 1
chr19_-_34255325 2.319 ENSMUST00000039631.8
Acta2
actin, alpha 2, smooth muscle, aorta
chr10_+_37139558 2.275 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr6_-_143947061 2.262 ENSMUST00000124233.1
Sox5
SRY-box containing gene 5
chr1_+_34005872 2.224 ENSMUST00000182296.1
Dst
dystonin

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 337 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 6.7 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.7 5.5 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.5 4.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 3.3 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 3.3 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.1 3.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.5 3.0 GO:0072318 clathrin coat disassembly(GO:0072318)
0.3 3.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 3.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 2.9 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.3 2.7 GO:0090527 actin filament reorganization(GO:0090527)
0.2 2.7 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.2 2.6 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 2.6 GO:0030010 establishment of cell polarity(GO:0030010)
0.6 2.5 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069)
0.1 2.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 2.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318) negative regulation of fibroblast migration(GO:0010764)
0.0 2.2 GO:0008033 tRNA processing(GO:0008033)
0.2 2.1 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2 2.1 GO:0070842 aggresome assembly(GO:0070842)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 142 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.5 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 6.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 4.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.7 3.0 GO:0031673 H zone(GO:0031673)
0.1 3.0 GO:0031430 M band(GO:0031430)
0.3 2.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 2.7 GO:0031941 filamentous actin(GO:0031941)
0.0 2.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.6 2.6 GO:0005874 microtubule(GO:0005874)
0.0 2.4 GO:0044295 axonal growth cone(GO:0044295)
0.7 2.0 GO:0043512 inhibin A complex(GO:0043512)
0.2 1.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.8 GO:0030427 site of polarized growth(GO:0030427)
0.0 1.7 GO:0070160 occluding junction(GO:0070160)
0.0 1.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.4 GO:0042383 sarcolemma(GO:0042383)
0.1 1.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.3 GO:0035327 transcriptionally active chromatin(GO:0035327)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 226 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 5.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 4.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.5 4.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 4.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 4.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.4 4.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 3.9 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 3.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 3.7 GO:0003779 actin binding(GO:0003779)
0.0 3.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.4 2.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 2.9 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 2.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 2.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 2.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.3 2.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 2.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 2.0 GO:0017137 Rab GTPase binding(GO:0017137)