Motif ID: Foxp2_Foxp3

Z-value: 0.780

Transcription factors associated with Foxp2_Foxp3:

Gene SymbolEntrez IDGene Name
Foxp2 ENSMUSG00000029563.10 Foxp2
Foxp3 ENSMUSG00000039521.6 Foxp3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxp2mm10_v2_chr6_+_15196949_15197102-0.687.7e-03Click!
Foxp3mm10_v2_chrX_+_7579666_75796930.263.7e-01Click!


Activity profile for motif Foxp2_Foxp3.

activity profile for motif Foxp2_Foxp3


Sorted Z-values histogram for motif Foxp2_Foxp3

Sorted Z-values for motif Foxp2_Foxp3



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxp2_Foxp3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_66386292 4.443 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr4_+_144892813 3.323 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr10_-_49783259 3.136 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
 Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr8_-_46294592 2.901 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr4_+_144893077 2.714 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr6_+_30541582 2.649 ENSMUST00000096066.4
 Cpa2
carboxypeptidase A2, pancreatic
chr15_+_3270767 2.519 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr18_+_69344503 2.511 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr3_+_118430299 2.353 ENSMUST00000180774.1
 Gm26871
predicted gene, 26871
chr3_+_5218546 2.321 ENSMUST00000026284.6
 Zfhx4
zinc finger homeodomain 4
chr3_+_52268337 2.224 ENSMUST00000053764.5
 Foxo1
forkhead box O1
chr4_+_144893127 2.171 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr6_+_141524379 1.989 ENSMUST00000032362.9
 Slco1c1
solute carrier organic anion transporter family, member 1c1
chr6_+_15185203 1.959 ENSMUST00000154448.1
 Foxp2
forkhead box P2
chr7_-_142372210 1.683 ENSMUST00000084412.5
 Ifitm10
interferon induced transmembrane protein 10
chr14_-_51913393 1.672 ENSMUST00000004673.7
ENSMUST00000111632.3
 Ndrg2

N-myc downstream regulated gene 2

chr14_-_55560340 1.654 ENSMUST00000066106.3
 A730061H03Rik
RIKEN cDNA A730061H03 gene
chr3_+_5218516 1.508 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4
chr7_+_19359740 1.497 ENSMUST00000140836.1
 Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr12_+_38780817 1.491 ENSMUST00000160856.1
 Etv1
ets variant gene 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 179 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 8.2 GO:0042572 retinol metabolic process(GO:0042572)
0.2 4.4 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.3 3.1 GO:0042118 endothelial cell activation(GO:0042118)
0.3 3.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 2.8 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.2 2.7 GO:0019835 cytolysis(GO:0019835)
0.2 2.6 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.4 2.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 2.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 2.4 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.7 2.2 GO:1901254 positive regulation of intracellular transport of viral material(GO:1901254)
0.3 2.2 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.2 2.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 1.5 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 1.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.3 1.4 GO:0001907 killing by symbiont of host cells(GO:0001907) induction of programmed cell death(GO:0012502) disruption by symbiont of host cell(GO:0044004) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 1.4 GO:0097421 liver regeneration(GO:0097421)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.9 GO:0005667 transcription factor complex(GO:0005667)
0.1 4.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 3.9 GO:0016605 PML body(GO:0016605)
0.5 3.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.5 2.5 GO:0097149 centralspindlin complex(GO:0097149)
0.5 2.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.7 2.2 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.6 GO:0045171 intercellular bridge(GO:0045171)
0.2 1.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.4 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.3 GO:0030478 actin cap(GO:0030478)
0.0 1.2 GO:0032590 dendrite membrane(GO:0032590)
0.1 1.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 1.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.0 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 0.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.8 GO:0000788 nuclear nucleosome(GO:0000788)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 115 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 8.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 4.7 GO:0042287 MHC protein binding(GO:0042287)
0.0 4.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 3.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.8 3.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 3.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 2.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 2.5 GO:0008430 selenium binding(GO:0008430)
0.1 2.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.4 2.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.5 2.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 1.8 GO:0005178 integrin binding(GO:0005178)
0.1 1.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 1.5 GO:0050693 LBD domain binding(GO:0050693)
0.1 1.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.4 GO:0045502 dynein binding(GO:0045502)
0.4 1.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)