Motif ID: Gata3

Z-value: 1.684


Transcription factors associated with Gata3:

Gene SymbolEntrez IDGene Name
Gata3 ENSMUSG00000015619.10 Gata3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gata3mm10_v2_chr2_-_9890026_9890035-0.488.0e-02Click!


Activity profile for motif Gata3.

activity profile for motif Gata3


Sorted Z-values histogram for motif Gata3

Sorted Z-values for motif Gata3



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_153665666 3.528 ENSMUST00000111814.1
ENSMUST00000111810.1
 Rgs8

regulator of G-protein signaling 8

chr6_+_88724828 2.950 ENSMUST00000089449.2
 Mgll
monoglyceride lipase
chr15_+_74516196 2.868 ENSMUST00000042035.9
 Bai1
brain-specific angiogenesis inhibitor 1
chr11_-_95514570 2.717 ENSMUST00000058866.7
 Nxph3
neurexophilin 3
chr3_-_103737995 2.543 ENSMUST00000029440.8
 Olfml3
olfactomedin-like 3
chr15_-_45114926 2.531 ENSMUST00000022967.5
 Kcnv1
potassium channel, subfamily V, member 1
chr1_-_25829511 2.386 ENSMUST00000135518.1
ENSMUST00000151309.1
 Bai3

brain-specific angiogenesis inhibitor 3

chr4_+_102589687 2.385 ENSMUST00000097949.4
ENSMUST00000106901.1
 Pde4b

phosphodiesterase 4B, cAMP specific

chr12_-_67221221 2.376 ENSMUST00000178814.1
ENSMUST00000179345.2
 Mdga2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr2_+_96318014 2.340 ENSMUST00000135431.1
ENSMUST00000162807.2
 Lrrc4c

leucine rich repeat containing 4C

chr1_-_119053339 2.292 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
 Gli2


GLI-Kruppel family member GLI2


chr1_+_153665587 2.291 ENSMUST00000147700.1
 Rgs8
regulator of G-protein signaling 8
chr15_-_67113909 2.248 ENSMUST00000092640.5
 St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr9_-_16378231 2.166 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr1_-_155417394 2.114 ENSMUST00000111775.1
ENSMUST00000111774.1
 Xpr1

xenotropic and polytropic retrovirus receptor 1

chr1_-_119053619 2.011 ENSMUST00000062483.8
 Gli2
GLI-Kruppel family member GLI2
chr1_+_153665627 2.005 ENSMUST00000147482.1
 Rgs8
regulator of G-protein signaling 8
chr2_+_136892168 1.980 ENSMUST00000099311.2
 Slx4ip
SLX4 interacting protein
chr7_-_75308373 1.947 ENSMUST00000085164.5
 Sv2b
synaptic vesicle glycoprotein 2 b
chr11_+_102604370 1.885 ENSMUST00000057893.5
 Fzd2
frizzled homolog 2 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 342 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 7.8 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.7 4.6 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.1 4.3 GO:0060032 notochord regression(GO:0060032)
0.7 3.7 GO:0015671 oxygen transport(GO:0015671)
0.6 3.7 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 3.6 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.2 3.2 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 3.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.2 3.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.4 2.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 2.7 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.2 2.4 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 2.4 GO:0010842 retina layer formation(GO:0010842)
0.1 2.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 2.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.4 1.9 GO:0007223 muscular septum morphogenesis(GO:0003150) Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1 1.9 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 1.9 GO:0060612 adipose tissue development(GO:0060612)
0.1 1.8 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.3 1.7 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 151 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 4.7 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.3 4.5 GO:0097542 ciliary tip(GO:0097542)
0.1 4.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 3.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.6 GO:0043198 dendritic shaft(GO:0043198)
0.4 3.4 GO:0005833 hemoglobin complex(GO:0005833)
0.1 3.1 GO:0031430 M band(GO:0031430)
0.2 2.8 GO:0043196 varicosity(GO:0043196)
0.0 2.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.5 GO:0043195 terminal bouton(GO:0043195)
0.1 2.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.4 GO:0060077 inhibitory synapse(GO:0060077)
0.1 2.3 GO:0030673 axolemma(GO:0030673)
0.1 2.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 2.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.8 GO:0043204 perikaryon(GO:0043204)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 1.6 GO:0005643 nuclear pore(GO:0005643)
0.2 1.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 212 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.7 3.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.5 3.7 GO:0001618 virus receptor activity(GO:0001618)
0.1 3.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 3.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 3.1 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.2 3.0 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 2.9 GO:0008565 protein transporter activity(GO:0008565)
0.2 2.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 2.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 2.6 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 2.4 GO:0005518 collagen binding(GO:0005518)
0.0 2.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.3 2.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 2.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 2.0 GO:0030552 cAMP binding(GO:0030552)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 1.6 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)