Motif ID: Gata4

Z-value: 0.566


Transcription factors associated with Gata4:

Gene SymbolEntrez IDGene Name
Gata4 ENSMUSG00000021944.9 Gata4



Activity profile for motif Gata4.

activity profile for motif Gata4


Sorted Z-values histogram for motif Gata4

Sorted Z-values for motif Gata4



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata4

PNG image of the network

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Top targets:


Showing 1 to 20 of 132 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_73191848 1.839 ENSMUST00000176910.1
 Fryl
furry homolog-like (Drosophila)
chr4_+_13751297 1.125 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_+_102570065 0.809 ENSMUST00000097950.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr4_+_102254739 0.764 ENSMUST00000106907.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr16_-_34263179 0.729 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chr2_+_71786923 0.689 ENSMUST00000112101.1
ENSMUST00000028522.3
 Itga6

integrin alpha 6

chr12_+_95692212 0.651 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr16_-_34262830 0.648 ENSMUST00000114947.1
 Kalrn
kalirin, RhoGEF kinase
chr16_-_34262945 0.611 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase
chr4_+_102254993 0.599 ENSMUST00000106908.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr1_+_179803376 0.590 ENSMUST00000097454.2
 Gm10518
predicted gene 10518
chr1_+_180851131 0.577 ENSMUST00000038091.6
 Sde2
SDE2 telomere maintenance homolog (S. pombe)
chr2_+_65845833 0.547 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr8_+_45627946 0.542 ENSMUST00000145458.1
 Sorbs2
sorbin and SH3 domain containing 2
chr9_+_66350465 0.542 ENSMUST00000042824.6
 Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr14_+_75455957 0.538 ENSMUST00000164848.1
 Siah3
seven in absentia homolog 3 (Drosophila)
chr16_+_58670208 0.530 ENSMUST00000060077.5
 Cpox
coproporphyrinogen oxidase
chr3_+_96596628 0.513 ENSMUST00000058943.7
 Ankrd34a
ankyrin repeat domain 34A
chr10_-_62342674 0.476 ENSMUST00000143179.1
ENSMUST00000130422.1
 Hk1

hexokinase 1

chr6_-_127109517 0.457 ENSMUST00000039913.8
 9630033F20Rik
RIKEN cDNA 9630033F20 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.2 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 2.0 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 1.8 GO:0090527 actin filament reorganization(GO:0090527)
0.0 1.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.8 GO:0019532 oxalate transport(GO:0019532)
0.0 0.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 0.7 GO:0035878 nail development(GO:0035878)
0.1 0.7 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.7 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.5 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.5 GO:0010359 regulation of anion channel activity(GO:0010359)
0.0 0.5 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.5 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.4 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0 0.4 GO:0050957 equilibrioception(GO:0050957)
0.1 0.3 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.1 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.4 GO:0002139 stereocilia coupling link(GO:0002139)
0.1 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.2 GO:0030552 cAMP binding(GO:0030552)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.5 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0050733 RS domain binding(GO:0050733)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)