Motif ID: Gata6

Z-value: 0.398


Transcription factors associated with Gata6:

Gene SymbolEntrez IDGene Name
Gata6 ENSMUSG00000005836.8 Gata6



Activity profile for motif Gata6.

activity profile for motif Gata6


Sorted Z-values histogram for motif Gata6

Sorted Z-values for motif Gata6



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata6

PNG image of the network

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Top targets:


Showing 1 to 20 of 70 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_95692212 0.920 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr6_+_58833689 0.896 ENSMUST00000041401.8
Herc3
hect domain and RLD 3
chr11_+_67586675 0.869 ENSMUST00000108680.1
Gas7
growth arrest specific 7
chr7_-_103853199 0.852 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr2_+_71786923 0.745 ENSMUST00000112101.1
ENSMUST00000028522.3
Itga6

integrin alpha 6

chr1_-_25829511 0.731 ENSMUST00000135518.1
ENSMUST00000151309.1
Bai3

brain-specific angiogenesis inhibitor 3

chr6_+_58831748 0.713 ENSMUST00000126292.1
ENSMUST00000031823.5
Herc3

hect domain and RLD 3

chr2_+_68104671 0.678 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr2_+_80617045 0.638 ENSMUST00000028384.4
Dusp19
dual specificity phosphatase 19
chr8_-_122699066 0.615 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr9_+_66350465 0.590 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr4_+_13751297 0.551 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_+_45628176 0.536 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr17_+_71204647 0.527 ENSMUST00000126681.1
Lpin2
lipin 2
chr5_-_73191848 0.514 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr8_+_45627709 0.502 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr2_+_65930117 0.465 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr8_+_45627946 0.446 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr1_+_179803376 0.434 ENSMUST00000097454.2
Gm10518
predicted gene 10518
chr16_-_46010212 0.381 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 1.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 0.9 GO:0015671 oxygen transport(GO:0015671)
0.2 0.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 0.7 GO:0035878 nail development(GO:0035878)
0.0 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.6 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.5 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.4 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.4 GO:0010225 response to UV-C(GO:0010225)
0.1 0.3 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)

Gene overrepresentation in cellular_component category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.9 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)

Gene overrepresentation in molecular_function category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.9 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.7 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.3 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)