Motif ID: Gata6

Z-value: 0.398


Transcription factors associated with Gata6:

Gene SymbolEntrez IDGene Name
Gata6 ENSMUSG00000005836.8 Gata6



Activity profile for motif Gata6.

activity profile for motif Gata6


Sorted Z-values histogram for motif Gata6

Sorted Z-values for motif Gata6



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_95692212 0.920 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr6_+_58833689 0.896 ENSMUST00000041401.8
Herc3
hect domain and RLD 3
chr11_+_67586675 0.869 ENSMUST00000108680.1
Gas7
growth arrest specific 7
chr7_-_103853199 0.852 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr2_+_71786923 0.745 ENSMUST00000112101.1
ENSMUST00000028522.3
Itga6

integrin alpha 6

chr1_-_25829511 0.731 ENSMUST00000135518.1
ENSMUST00000151309.1
Bai3

brain-specific angiogenesis inhibitor 3

chr6_+_58831748 0.713 ENSMUST00000126292.1
ENSMUST00000031823.5
Herc3

hect domain and RLD 3

chr2_+_68104671 0.678 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr2_+_80617045 0.638 ENSMUST00000028384.4
Dusp19
dual specificity phosphatase 19
chr8_-_122699066 0.615 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr9_+_66350465 0.590 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr4_+_13751297 0.551 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_+_45628176 0.536 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr17_+_71204647 0.527 ENSMUST00000126681.1
Lpin2
lipin 2
chr5_-_73191848 0.514 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr8_+_45627709 0.502 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr2_+_65930117 0.465 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr8_+_45627946 0.446 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr1_+_179803376 0.434 ENSMUST00000097454.2
Gm10518
predicted gene 10518
chr16_-_46010212 0.381 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr16_-_34262945 0.372 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr6_-_127109517 0.364 ENSMUST00000039913.8
9630033F20Rik
RIKEN cDNA 9630033F20 gene
chr7_-_119895446 0.360 ENSMUST00000098080.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr16_+_58670208 0.356 ENSMUST00000060077.5
Cpox
coproporphyrinogen oxidase
chr5_+_121777929 0.347 ENSMUST00000160821.1
Atxn2
ataxin 2
chr17_-_33713372 0.346 ENSMUST00000173392.1
March2
membrane-associated ring finger (C3HC4) 2
chr2_-_7396192 0.330 ENSMUST00000137733.2
Celf2
CUGBP, Elav-like family member 2
chr11_+_4883186 0.329 ENSMUST00000139737.1
Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr2_-_7395879 0.314 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr19_+_4711153 0.307 ENSMUST00000008991.6
Sptbn2
spectrin beta, non-erythrocytic 2
chr2_-_7081207 0.280 ENSMUST00000114923.2
ENSMUST00000182706.1
Celf2

CUGBP, Elav-like family member 2

chr11_-_53707269 0.260 ENSMUST00000124352.1
ENSMUST00000020649.7
Rad50

RAD50 homolog (S. cerevisiae)

chr6_+_86078070 0.258 ENSMUST00000032069.5
Add2
adducin 2 (beta)
chr4_-_110287479 0.232 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr11_+_95712673 0.230 ENSMUST00000107717.1
Zfp652
zinc finger protein 652
chr1_+_45311538 0.211 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr8_-_64205970 0.209 ENSMUST00000066166.4
Tll1
tolloid-like
chr10_+_40883469 0.201 ENSMUST00000019975.7
Wasf1
WAS protein family, member 1
chr17_+_34604819 0.155 ENSMUST00000173242.1
Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr2_-_7081256 0.143 ENSMUST00000183209.1
Celf2
CUGBP, Elav-like family member 2
chr10_+_52417532 0.142 ENSMUST00000023830.8
Nus1
nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
chr6_-_38124568 0.140 ENSMUST00000040259.4
Atp6v0a4
ATPase, H+ transporting, lysosomal V0 subunit A4
chr9_+_65032413 0.140 ENSMUST00000034960.6
Dpp8
dipeptidylpeptidase 8
chr1_-_173333503 0.134 ENSMUST00000038227.4
Darc
Duffy blood group, chemokine receptor
chr9_+_62342449 0.127 ENSMUST00000156461.1
Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr9_+_44379490 0.125 ENSMUST00000066601.6
Hyou1
hypoxia up-regulated 1
chr11_-_102365111 0.123 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr15_-_103251465 0.120 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
Nfe2




nuclear factor, erythroid derived 2




chr10_-_40883073 0.119 ENSMUST00000044166.7
Cdc40
cell division cycle 40
chr9_-_65827544 0.119 ENSMUST00000159109.1
Zfp609
zinc finger protein 609
chr1_+_152954966 0.113 ENSMUST00000043313.8
Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr11_+_3330781 0.113 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr10_-_62342674 0.109 ENSMUST00000143179.1
ENSMUST00000130422.1
Hk1

hexokinase 1

chr7_+_119900099 0.103 ENSMUST00000106516.1
Lyrm1
LYR motif containing 1
chr11_-_70220969 0.102 ENSMUST00000060010.2
Slc16a13
solute carrier family 16 (monocarboxylic acid transporters), member 13
chrX_-_37110257 0.100 ENSMUST00000076265.6
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr3_-_20242173 0.097 ENSMUST00000001921.1
Cpa3
carboxypeptidase A3, mast cell
chr2_+_110597298 0.075 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr2_-_7395968 0.052 ENSMUST00000002176.6
Celf2
CUGBP, Elav-like family member 2
chr4_-_46404224 0.047 ENSMUST00000107764.2
Hemgn
hemogen
chr6_-_7983424 0.044 ENSMUST00000178598.1
Gm9825
predicted gene 9825
chr5_+_76840597 0.037 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
C530008M17Rik


RIKEN cDNA C530008M17 gene


chr18_-_43477764 0.032 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr2_+_143915273 0.027 ENSMUST00000103172.3
Dstn
destrin
chr2_+_125859134 0.021 ENSMUST00000028636.6
ENSMUST00000125084.1
Galk2

galactokinase 2

chr3_-_92429403 0.021 ENSMUST00000047300.7
Gm9774
predicted pseudogene 9774
chr13_+_24802020 0.018 ENSMUST00000155575.1
BC005537
cDNA sequence BC005537
chr15_-_83170168 0.012 ENSMUST00000162834.1
Cyb5r3
cytochrome b5 reductase 3
chr16_+_44943737 0.006 ENSMUST00000114622.3
ENSMUST00000166731.1
Cd200r3

CD200 receptor 3

chr18_+_76059458 0.003 ENSMUST00000167921.1
Zbtb7c
zinc finger and BTB domain containing 7C

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0035878 nail development(GO:0035878)
0.2 0.9 GO:0015671 oxygen transport(GO:0015671)
0.2 0.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.6 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.3 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.1 0.5 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.4 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 1.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 1.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 1.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0010359 regulation of anion channel activity(GO:0010359)
0.0 0.4 GO:0010225 response to UV-C(GO:0010225)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
0.0 0.1 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.1 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.2 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.7 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.3 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)