Motif ID: Gbx2

Z-value: 0.633


Transcription factors associated with Gbx2:

Gene SymbolEntrez IDGene Name
Gbx2 ENSMUSG00000034486.7 Gbx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gbx2mm10_v2_chr1_-_89933290_899332900.263.8e-01Click!


Activity profile for motif Gbx2.

activity profile for motif Gbx2


Sorted Z-values histogram for motif Gbx2

Sorted Z-values for motif Gbx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Gbx2

PNG image of the network

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Top targets:


Showing 1 to 20 of 50 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_59170978 1.923 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr14_-_48667508 1.898 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr8_-_21906412 1.283 ENSMUST00000051965.4
Defb11
defensin beta 11
chr3_-_116129615 0.884 ENSMUST00000029574.8
Vcam1
vascular cell adhesion molecule 1
chr13_-_97747373 0.694 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr13_-_97747399 0.664 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr18_+_56432116 0.663 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chrM_-_14060 0.660 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr5_-_111761697 0.645 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
E130006D01Rik


RIKEN cDNA E130006D01 gene


chr11_-_79504078 0.600 ENSMUST00000164465.2
Omg
oligodendrocyte myelin glycoprotein
chr13_+_49544443 0.576 ENSMUST00000177948.1
ENSMUST00000021820.6
Aspn

asporin

chr3_-_113577743 0.548 ENSMUST00000067980.5
Amy1
amylase 1, salivary
chr13_+_31806627 0.545 ENSMUST00000062292.2
Foxc1
forkhead box C1
chr16_-_36784924 0.496 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr2_+_152754156 0.467 ENSMUST00000010020.5
Cox4i2
cytochrome c oxidase subunit IV isoform 2
chr16_-_36784784 0.459 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr17_-_36032682 0.454 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr12_+_111814170 0.449 ENSMUST00000021714.7
Zfyve21
zinc finger, FYVE domain containing 21
chr13_+_23763660 0.439 ENSMUST00000055770.1
Hist1h1a
histone cluster 1, H1a
chr11_+_59306920 0.437 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a

wingless-type MMTV integration site 9A


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 1.9 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.2 1.9 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.2 1.0 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.9 GO:0061032 chorio-allantoic fusion(GO:0060710) visceral serous pericardium development(GO:0061032)
0.1 0.6 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.6 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.2 0.5 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.2 0.5 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.4 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.1 0.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.3 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.3 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.0 0.2 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0 0.2 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.1 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.9 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 1.0 GO:0042895 antibiotic transporter activity(GO:0042895)
0.2 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 0.5 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.5 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.4 GO:0000150 recombinase activity(GO:0000150)
0.1 0.4 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.1 0.3 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)