Motif ID: Gcm1

Z-value: 0.718


Transcription factors associated with Gcm1:

Gene SymbolEntrez IDGene Name
Gcm1 ENSMUSG00000023333.7 Gcm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gcm1mm10_v2_chr9_+_78051938_780519580.253.9e-01Click!


Activity profile for motif Gcm1.

activity profile for motif Gcm1


Sorted Z-values histogram for motif Gcm1

Sorted Z-values for motif Gcm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gcm1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_119238794 2.529 ENSMUST00000026360.8
 Itgb8
integrin beta 8
chr19_+_53529100 1.729 ENSMUST00000038287.6
 Dusp5
dual specificity phosphatase 5
chr8_-_45358737 1.592 ENSMUST00000155230.1
ENSMUST00000135912.1
 Fam149a

family with sequence similarity 149, member A

chr2_+_169633517 1.297 ENSMUST00000109157.1
 Tshz2
teashirt zinc finger family member 2
chr2_+_128126030 1.279 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
 Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr14_-_66213552 1.110 ENSMUST00000178730.1
 Ptk2b
PTK2 protein tyrosine kinase 2 beta
chr19_+_6400523 0.979 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
 Rasgrp2



RAS, guanyl releasing protein 2



chrX_+_93286499 0.913 ENSMUST00000046565.7
ENSMUST00000113947.2
 Arx

aristaless related homeobox

chr19_+_6400611 0.778 ENSMUST00000113467.1
 Rasgrp2
RAS, guanyl releasing protein 2
chr17_+_23679363 0.699 ENSMUST00000024699.2
 Cldn6
claudin 6
chr15_-_10470490 0.682 ENSMUST00000136591.1
 Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr11_+_101246960 0.657 ENSMUST00000107282.3
 Ramp2
receptor (calcitonin) activity modifying protein 2
chr11_-_6065538 0.638 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr4_-_136956784 0.627 ENSMUST00000030420.8
 Epha8
Eph receptor A8
chr15_-_75747922 0.580 ENSMUST00000062002.4
 Mafa
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr7_-_99182681 0.580 ENSMUST00000033001.4
 Dgat2
diacylglycerol O-acyltransferase 2
chr15_+_79348061 0.551 ENSMUST00000163691.1
 Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr1_+_43092588 0.527 ENSMUST00000039080.3
 8430432A02Rik
RIKEN cDNA 8430432A02 gene
chr17_+_25471564 0.518 ENSMUST00000025002.1
 Tekt4
tektin 4
chr8_+_105170668 0.451 ENSMUST00000109395.1
ENSMUST00000109394.1
ENSMUST00000052209.2
ENSMUST00000109392.1
 Cbfb



core binding factor beta



chr13_-_95250166 0.425 ENSMUST00000162153.1
ENSMUST00000160957.2
ENSMUST00000159598.1
ENSMUST00000162412.1
 Pde8b



phosphodiesterase 8B



chr13_-_100108337 0.366 ENSMUST00000180822.1
 BC001981
cDNA sequence BC001981
chr17_+_24696234 0.339 ENSMUST00000019464.7
 Noxo1
NADPH oxidase organizer 1
chr1_-_79761752 0.311 ENSMUST00000113512.1
ENSMUST00000113513.1
ENSMUST00000113515.1
ENSMUST00000113514.1
ENSMUST00000113510.1
ENSMUST00000113511.1
ENSMUST00000048820.7
 Wdfy1






WD repeat and FYVE domain containing 1






chr6_+_6863769 0.307 ENSMUST00000031768.6
 Dlx6
distal-less homeobox 6
chr13_+_8202922 0.304 ENSMUST00000123187.1
 Adarb2
adenosine deaminase, RNA-specific, B2
chr11_-_121354337 0.284 ENSMUST00000106110.3
ENSMUST00000136797.1
ENSMUST00000026173.6
 Wdr45b


WD repeat domain 45B


chr11_-_106613370 0.274 ENSMUST00000128933.1
 Tex2
testis expressed gene 2
chr19_+_46761578 0.270 ENSMUST00000077666.4
ENSMUST00000099373.4
 Cnnm2

cyclin M2

chr13_+_100108155 0.254 ENSMUST00000129014.1
 Serf1
small EDRK-rich factor 1
chr17_-_6948283 0.248 ENSMUST00000024572.9
 Rsph3b
radial spoke 3B homolog (Chlamydomonas)
chr13_+_100107997 0.235 ENSMUST00000142155.1
ENSMUST00000022145.8
ENSMUST00000132053.1
 Serf1


small EDRK-rich factor 1


chr13_+_8202860 0.226 ENSMUST00000064473.6
 Adarb2
adenosine deaminase, RNA-specific, B2
chr12_+_8674224 0.226 ENSMUST00000111122.2
 Pum2
pumilio 2 (Drosophila)
chrX_+_73503074 0.216 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
 Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr7_+_46396439 0.193 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr9_-_70657121 0.183 ENSMUST00000049031.5
 Fam63b
family with sequence similarity 63, member B
chr6_-_113501818 0.164 ENSMUST00000101059.1
 Prrt3
proline-rich transmembrane protein 3
chr3_-_69598822 0.155 ENSMUST00000061826.1
 B3galnt1
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
chr8_+_13339656 0.143 ENSMUST00000170909.1
 Tfdp1
transcription factor Dp 1
chrX_+_7657260 0.135 ENSMUST00000033485.7
 Prickle3
prickle homolog 3 (Drosophila)
chr16_+_38902305 0.133 ENSMUST00000023478.7
 Igsf11
immunoglobulin superfamily, member 11
chr2_-_39226343 0.132 ENSMUST00000028087.3
 Ppp6c
protein phosphatase 6, catalytic subunit
chr8_+_91070052 0.131 ENSMUST00000034091.7
 Rbl2
retinoblastoma-like 2
chr14_-_32201869 0.130 ENSMUST00000170331.1
ENSMUST00000013845.6
 Timm23

translocase of inner mitochondrial membrane 23

chr13_+_8202885 0.121 ENSMUST00000139438.1
ENSMUST00000135574.1
 Adarb2

adenosine deaminase, RNA-specific, B2

chr11_+_120491840 0.118 ENSMUST00000026899.3
 Slc25a10
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr2_+_105904629 0.116 ENSMUST00000037499.5
 Immp1l
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chrX_-_75130914 0.109 ENSMUST00000114091.1
 Mpp1
membrane protein, palmitoylated
chr7_+_4922251 0.092 ENSMUST00000047309.5
 Nat14
N-acetyltransferase 14
chr12_+_8674129 0.082 ENSMUST00000111123.2
ENSMUST00000178015.1
ENSMUST00000020915.3
 Pum2


pumilio 2 (Drosophila)


chr11_-_60352869 0.080 ENSMUST00000095254.5
ENSMUST00000102683.4
ENSMUST00000093048.6
ENSMUST00000093046.6
ENSMUST00000064019.8
ENSMUST00000102682.4
 Tom1l2





target of myb1-like 2 (chicken)





chr18_-_39487096 0.060 ENSMUST00000097592.2
ENSMUST00000115571.1
 Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr14_+_55578360 0.046 ENSMUST00000174259.1
ENSMUST00000174563.1
ENSMUST00000089619.6
ENSMUST00000172738.1
 Psme1



proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)



chr2_-_105904484 0.044 ENSMUST00000122965.1
 Elp4
elongation protein 4 homolog (S. cerevisiae)
chr11_+_116918844 0.037 ENSMUST00000103027.3
 Mgat5b
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr4_-_156234777 0.037 ENSMUST00000105569.3
 Klhl17
kelch-like 17
chr17_+_8311101 0.022 ENSMUST00000154553.1
 Sft2d1
SFT2 domain containing 1
chr7_-_101011976 0.021 ENSMUST00000178340.1
ENSMUST00000037540.3
 P2ry2

purinergic receptor P2Y, G-protein coupled 2

chr6_+_86365673 0.016 ENSMUST00000071492.7
 Fam136a
family with sequence similarity 136, member A
chr2_+_48814109 0.015 ENSMUST00000063886.3
 Acvr2a
activin receptor IIA
chr3_+_89459325 0.014 ENSMUST00000107410.1
 Pmvk
phosphomevalonate kinase
chr16_+_36875119 0.003 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
 Golgb1


Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1


golgi autoantigen, golgin subfamily b, macrogolgin 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0010752 signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752)
0.3 1.3 GO:0001907 killing by symbiont of host cells(GO:0001907) induction of programmed cell death(GO:0012502) disruption by symbiont of host cell(GO:0044004) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of fibroblast apoptotic process(GO:2000271)
0.3 0.9 GO:0021759 globus pallidus development(GO:0021759)
0.2 0.6 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.1 0.4 GO:0035106 operant conditioning(GO:0035106)
0.1 0.6 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 2.5 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 0.6 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.3 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.1 0.7 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 0.5 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 0.3 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 1.7 GO:0001706 endoderm formation(GO:0001706)
0.0 1.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0015744 succinate transport(GO:0015744)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.6 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.6 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.3 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 2.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.6 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 1.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 1.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.7 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.7 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.6 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.1 GO:0045502 dynein binding(GO:0045502)
0.0 0.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0015266 protein channel activity(GO:0015266)
0.0 0.0 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)