Motif ID: Gcm1

Z-value: 0.718


Transcription factors associated with Gcm1:

Gene SymbolEntrez IDGene Name
Gcm1 ENSMUSG00000023333.7 Gcm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gcm1mm10_v2_chr9_+_78051938_780519580.253.9e-01Click!


Activity profile for motif Gcm1.

activity profile for motif Gcm1


Sorted Z-values histogram for motif Gcm1

Sorted Z-values for motif Gcm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gcm1

PNG image of the network

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Top targets:


Showing 1 to 20 of 63 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_119238794 2.529 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr19_+_53529100 1.729 ENSMUST00000038287.6
Dusp5
dual specificity phosphatase 5
chr8_-_45358737 1.592 ENSMUST00000155230.1
ENSMUST00000135912.1
Fam149a

family with sequence similarity 149, member A

chr2_+_169633517 1.297 ENSMUST00000109157.1
Tshz2
teashirt zinc finger family member 2
chr2_+_128126030 1.279 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr14_-_66213552 1.110 ENSMUST00000178730.1
Ptk2b
PTK2 protein tyrosine kinase 2 beta
chr19_+_6400523 0.979 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
Rasgrp2



RAS, guanyl releasing protein 2



chrX_+_93286499 0.913 ENSMUST00000046565.7
ENSMUST00000113947.2
Arx

aristaless related homeobox

chr19_+_6400611 0.778 ENSMUST00000113467.1
Rasgrp2
RAS, guanyl releasing protein 2
chr17_+_23679363 0.699 ENSMUST00000024699.2
Cldn6
claudin 6
chr15_-_10470490 0.682 ENSMUST00000136591.1
Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr11_+_101246960 0.657 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr11_-_6065538 0.638 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr4_-_136956784 0.627 ENSMUST00000030420.8
Epha8
Eph receptor A8
chr15_-_75747922 0.580 ENSMUST00000062002.4
Mafa
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr7_-_99182681 0.580 ENSMUST00000033001.4
Dgat2
diacylglycerol O-acyltransferase 2
chr15_+_79348061 0.551 ENSMUST00000163691.1
Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr1_+_43092588 0.527 ENSMUST00000039080.3
8430432A02Rik
RIKEN cDNA 8430432A02 gene
chr17_+_25471564 0.518 ENSMUST00000025002.1
Tekt4
tektin 4
chr8_+_105170668 0.451 ENSMUST00000109395.1
ENSMUST00000109394.1
ENSMUST00000052209.2
ENSMUST00000109392.1
Cbfb



core binding factor beta




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.5 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 1.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.7 GO:0001706 endoderm formation(GO:0001706)
0.3 1.3 GO:0001907 killing by symbiont of host cells(GO:0001907) induction of programmed cell death(GO:0012502) disruption by symbiont of host cell(GO:0044004) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of fibroblast apoptotic process(GO:2000271)
0.4 1.1 GO:0010752 signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752)
0.3 0.9 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.7 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.2 0.6 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.1 0.6 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 0.6 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.6 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.6 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.5 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.4 GO:0035106 operant conditioning(GO:0035106)
0.1 0.3 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.1 0.3 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0022617 extracellular matrix disassembly(GO:0022617)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.2 1.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0051233 spindle midzone(GO:0051233)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 1.1 GO:0045502 dynein binding(GO:0045502)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.7 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.7 GO:0015026 coreceptor activity(GO:0015026)
0.2 0.6 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.6 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.1 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0015266 protein channel activity(GO:0015266)
0.0 0.0 GO:0031208 POZ domain binding(GO:0031208)