Motif ID: Gfi1_Gfi1b

Z-value: 1.656

Transcription factors associated with Gfi1_Gfi1b:

Gene SymbolEntrez IDGene Name
Gfi1 ENSMUSG00000029275.11 Gfi1
Gfi1b ENSMUSG00000026815.8 Gfi1b



Activity profile for motif Gfi1_Gfi1b.

activity profile for motif Gfi1_Gfi1b


Sorted Z-values histogram for motif Gfi1_Gfi1b

Sorted Z-values for motif Gfi1_Gfi1b



Network of associatons between targets according to the STRING database.



First level regulatory network of Gfi1_Gfi1b

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_3027439 4.299 ENSMUST00000177875.1
ENSMUST00000179982.1
 Gm10717

predicted gene 10717

chr9_+_3000922 4.282 ENSMUST00000151376.2
 Gm10722
predicted gene 10722
chr9_+_3005125 4.071 ENSMUST00000179881.1
 Gm11168
predicted gene 11168
chr9_+_3013140 3.904 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr9_+_3034599 3.630 ENSMUST00000178641.1
 Gm17535
predicted gene, 17535
chr9_+_3023547 3.344 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr9_+_3017408 3.342 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr9_+_3015654 3.290 ENSMUST00000099050.3
 Gm10720
predicted gene 10720
chr9_+_3025417 3.261 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr9_+_3037111 2.951 ENSMUST00000177969.1
 Gm10715
predicted gene 10715
chr9_+_3036877 2.732 ENSMUST00000155807.2
 Gm10715
predicted gene 10715
chr9_+_3004457 2.413 ENSMUST00000178348.1
 Gm11168
predicted gene 11168
chr9_+_3018753 2.141 ENSMUST00000179272.1
 Gm10719
predicted gene 10719
chr3_+_54361103 1.906 ENSMUST00000107985.3
ENSMUST00000117373.1
ENSMUST00000073012.6
ENSMUST00000081564.6
 Postn



periostin, osteoblast specific factor



chr6_+_121300227 1.585 ENSMUST00000064580.7
 Slc6a13
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr16_+_38089001 1.349 ENSMUST00000023507.6
 Gsk3b
glycogen synthase kinase 3 beta
chr10_+_102158858 1.337 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
 Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr13_+_16011851 1.268 ENSMUST00000042603.6
 Inhba
inhibin beta-A
chrX_+_140367494 1.142 ENSMUST00000141660.1
 Frmpd3
FERM and PDZ domain containing 3
chr3_+_88965812 1.098 ENSMUST00000090933.4
 Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 147 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.9 GO:0006491 N-glycan processing(GO:0006491)
0.1 2.2 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.3 1.9 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343)
0.0 1.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.3 1.7 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.5 1.5 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.1 1.5 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 1.5 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 1.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.4 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.4 1.3 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 1.2 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.0 1.2 GO:0030325 adrenal gland development(GO:0030325)
0.0 1.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 1.1 GO:0008542 visual learning(GO:0008542)
0.1 1.0 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.9 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.9 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 0.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.0 GO:0030027 lamellipodium(GO:0030027)
0.0 2.2 GO:0016605 PML body(GO:0016605)
0.0 2.1 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.4 1.3 GO:0043512 inhibin A complex(GO:0043512)
0.1 1.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.2 GO:0030118 clathrin coat(GO:0030118)
0.0 0.9 GO:0005801 cis-Golgi network(GO:0005801)
0.2 0.8 GO:0090537 CERF complex(GO:0090537)
0.1 0.8 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.7 GO:0005883 neurofilament(GO:0005883)
0.1 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 0.6 GO:0005588 collagen type V trimer(GO:0005588)
0.2 0.6 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.1 0.6 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.5 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 108 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 1.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.5 1.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 1.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.4 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.2 1.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 1.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.1 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.9 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.9 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.3 0.8 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.3 0.8 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 0.7 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.7 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.7 GO:0043559 insulin binding(GO:0043559)