Motif ID: Gmeb1

Z-value: 0.485


Transcription factors associated with Gmeb1:

Gene SymbolEntrez IDGene Name
Gmeb1 ENSMUSG00000028901.7 Gmeb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gmeb1mm10_v2_chr4_-_132261521_1322615720.723.6e-03Click!


Activity profile for motif Gmeb1.

activity profile for motif Gmeb1


Sorted Z-values histogram for motif Gmeb1

Sorted Z-values for motif Gmeb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gmeb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 86 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_7213897 1.120 ENSMUST00000020702.4
ENSMUST00000135887.2
 Igfbp3

insulin-like growth factor binding protein 3

chr2_-_157007015 0.429 ENSMUST00000146413.1
 Dsn1
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr18_+_36559972 0.408 ENSMUST00000134146.1
 Ankhd1
ankyrin repeat and KH domain containing 1
chr3_+_127553462 0.388 ENSMUST00000043108.4
 4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr8_+_26119611 0.340 ENSMUST00000140819.1
 Rnf170
ring finger protein 170
chr15_+_81400132 0.292 ENSMUST00000163754.1
ENSMUST00000041609.4
 Xpnpep3

X-prolyl aminopeptidase (aminopeptidase P) 3, putative

chr8_+_23139064 0.284 ENSMUST00000033947.8
 Ank1
ankyrin 1, erythroid
chr15_-_83724979 0.273 ENSMUST00000171496.1
ENSMUST00000043634.5
ENSMUST00000076060.5
ENSMUST00000016907.7
 Scube1



signal peptide, CUB domain, EGF-like 1



chr4_-_40269778 0.268 ENSMUST00000042575.6
 Topors
topoisomerase I binding, arginine/serine-rich
chr11_+_101009452 0.261 ENSMUST00000044721.6
ENSMUST00000103110.3
ENSMUST00000168757.2
 Atp6v0a1


ATPase, H+ transporting, lysosomal V0 subunit A1


chr8_-_25016743 0.258 ENSMUST00000084032.5
 Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr8_-_25016901 0.251 ENSMUST00000084035.5
 Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr12_+_4917376 0.243 ENSMUST00000045664.5
 Atad2b
ATPase family, AAA domain containing 2B
chr8_+_23139030 0.241 ENSMUST00000121075.1
 Ank1
ankyrin 1, erythroid
chr3_+_40800054 0.221 ENSMUST00000168287.1
 Plk4
polo-like kinase 4
chr7_+_5020376 0.217 ENSMUST00000076251.4
 Zfp865
zinc finger protein 865
chr6_+_90619241 0.204 ENSMUST00000032177.8
 Slc41a3
solute carrier family 41, member 3
chr3_-_127553233 0.192 ENSMUST00000029588.5
 Larp7
La ribonucleoprotein domain family, member 7
chr8_+_26119361 0.192 ENSMUST00000014022.8
ENSMUST00000153528.1
ENSMUST00000131138.1
ENSMUST00000110575.1
 Rnf170



ring finger protein 170



chr3_+_40800013 0.192 ENSMUST00000026858.5
ENSMUST00000170825.1
 Plk4

polo-like kinase 4


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.1 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.2 0.5 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.0 0.5 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.1 0.4 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.3 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.3 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.2 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.2 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.0 0.2 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.2 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.1 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661) regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 0.6 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)

Gene overrepresentation in molecular_function category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0032564 dATP binding(GO:0032564)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0045505 dynein intermediate chain binding(GO:0045505)