Motif ID: Gmeb1

Z-value: 0.485


Transcription factors associated with Gmeb1:

Gene SymbolEntrez IDGene Name
Gmeb1 ENSMUSG00000028901.7 Gmeb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gmeb1mm10_v2_chr4_-_132261521_1322615720.723.6e-03Click!


Activity profile for motif Gmeb1.

activity profile for motif Gmeb1


Sorted Z-values histogram for motif Gmeb1

Sorted Z-values for motif Gmeb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gmeb1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_7213897 1.120 ENSMUST00000020702.4
ENSMUST00000135887.2
 Igfbp3

insulin-like growth factor binding protein 3

chr2_-_157007015 0.429 ENSMUST00000146413.1
 Dsn1
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr18_+_36559972 0.408 ENSMUST00000134146.1
 Ankhd1
ankyrin repeat and KH domain containing 1
chr3_+_127553462 0.388 ENSMUST00000043108.4
 4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr8_+_26119611 0.340 ENSMUST00000140819.1
 Rnf170
ring finger protein 170
chr15_+_81400132 0.292 ENSMUST00000163754.1
ENSMUST00000041609.4
 Xpnpep3

X-prolyl aminopeptidase (aminopeptidase P) 3, putative

chr8_+_23139064 0.284 ENSMUST00000033947.8
 Ank1
ankyrin 1, erythroid
chr15_-_83724979 0.273 ENSMUST00000171496.1
ENSMUST00000043634.5
ENSMUST00000076060.5
ENSMUST00000016907.7
 Scube1



signal peptide, CUB domain, EGF-like 1



chr4_-_40269778 0.268 ENSMUST00000042575.6
 Topors
topoisomerase I binding, arginine/serine-rich
chr11_+_101009452 0.261 ENSMUST00000044721.6
ENSMUST00000103110.3
ENSMUST00000168757.2
 Atp6v0a1


ATPase, H+ transporting, lysosomal V0 subunit A1


chr8_-_25016743 0.258 ENSMUST00000084032.5
 Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr8_-_25016901 0.251 ENSMUST00000084035.5
 Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr12_+_4917376 0.243 ENSMUST00000045664.5
 Atad2b
ATPase family, AAA domain containing 2B
chr8_+_23139030 0.241 ENSMUST00000121075.1
 Ank1
ankyrin 1, erythroid
chr3_+_40800054 0.221 ENSMUST00000168287.1
 Plk4
polo-like kinase 4
chr7_+_5020376 0.217 ENSMUST00000076251.4
 Zfp865
zinc finger protein 865
chr6_+_90619241 0.204 ENSMUST00000032177.8
 Slc41a3
solute carrier family 41, member 3
chr3_-_127553233 0.192 ENSMUST00000029588.5
 Larp7
La ribonucleoprotein domain family, member 7
chr8_+_26119361 0.192 ENSMUST00000014022.8
ENSMUST00000153528.1
ENSMUST00000131138.1
ENSMUST00000110575.1
 Rnf170



ring finger protein 170



chr3_+_40800013 0.192 ENSMUST00000026858.5
ENSMUST00000170825.1
 Plk4

polo-like kinase 4

chr11_+_86544982 0.188 ENSMUST00000108030.2
ENSMUST00000020821.3
ENSMUST00000069503.6
ENSMUST00000167178.2
 Tubd1



tubulin, delta 1



chr9_-_45906837 0.180 ENSMUST00000161203.1
ENSMUST00000058720.5
ENSMUST00000160699.1
 Rnf214


ring finger protein 214


chr5_-_31291026 0.176 ENSMUST00000041565.7
 Ift172
intraflagellar transport 172
chr11_+_69095217 0.176 ENSMUST00000101004.2
 Per1
period circadian clock 1
chr11_+_53770458 0.175 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
 Irf1



interferon regulatory factor 1



chr11_-_40733373 0.171 ENSMUST00000020579.8
 Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr6_+_113531675 0.166 ENSMUST00000036340.5
ENSMUST00000101051.2
 Fancd2

Fanconi anemia, complementation group D2

chr7_+_5020561 0.164 ENSMUST00000085427.3
 Zfp865
zinc finger protein 865
chr16_-_87432597 0.158 ENSMUST00000039449.7
 Ltn1
listerin E3 ubiquitin protein ligase 1
chr3_+_95434386 0.144 ENSMUST00000102749.4
ENSMUST00000090804.5
ENSMUST00000107161.1
ENSMUST00000107160.1
ENSMUST00000015666.10
 Arnt




aryl hydrocarbon receptor nuclear translocator




chr3_-_108086590 0.143 ENSMUST00000102638.1
ENSMUST00000102637.1
 Ampd2

adenosine monophosphate deaminase 2

chr11_+_50025309 0.143 ENSMUST00000054684.7
ENSMUST00000102776.4
 Rnf130

ring finger protein 130

chr11_+_51263114 0.136 ENSMUST00000093132.6
ENSMUST00000109113.1
 Clk4

CDC like kinase 4

chr17_-_46327949 0.133 ENSMUST00000047970.7
 Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr2_-_157007039 0.130 ENSMUST00000103129.2
ENSMUST00000103130.1
 Dsn1

DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)

chr17_-_46327990 0.129 ENSMUST00000167360.1
 Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr17_+_83350925 0.124 ENSMUST00000096766.4
ENSMUST00000112363.2
ENSMUST00000049503.8
 Eml4


echinoderm microtubule associated protein like 4


chr11_+_83302641 0.123 ENSMUST00000176430.1
ENSMUST00000065692.7
 Ap2b1

adaptor-related protein complex 2, beta 1 subunit

chr15_-_81399594 0.120 ENSMUST00000023039.8
 St13
suppression of tumorigenicity 13
chr11_-_83302586 0.113 ENSMUST00000176374.1
 Pex12
peroxisomal biogenesis factor 12
chr18_+_23954668 0.108 ENSMUST00000060762.4
 Zfp397
zinc finger protein 397
chr17_-_85090204 0.107 ENSMUST00000072406.3
ENSMUST00000171795.1
 Prepl

prolyl endopeptidase-like

chr4_-_126202583 0.102 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
 Thrap3


thyroid hormone receptor associated protein 3


chr11_+_83302817 0.102 ENSMUST00000142680.1
 Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr1_+_82316452 0.102 ENSMUST00000027322.7
 Rhbdd1
rhomboid domain containing 1
chr18_-_53744509 0.102 ENSMUST00000049811.6
 Cep120
centrosomal protein 120
chr3_+_138143483 0.096 ENSMUST00000162864.1
 Trmt10a
tRNA methyltransferase 10A
chr4_-_135353126 0.096 ENSMUST00000030613.4
ENSMUST00000131373.1
 Srrm1

serine/arginine repetitive matrix 1

chr15_-_58135047 0.092 ENSMUST00000038194.3
 Atad2
ATPase family, AAA domain containing 2
chr4_-_135353164 0.091 ENSMUST00000084846.5
ENSMUST00000136342.2
ENSMUST00000105861.1
 Srrm1


serine/arginine repetitive matrix 1


chr2_+_75659253 0.089 ENSMUST00000111964.1
ENSMUST00000111962.1
ENSMUST00000111961.1
ENSMUST00000164947.2
ENSMUST00000090792.4
 Hnrnpa3




heterogeneous nuclear ribonucleoprotein A3




chr4_+_40970906 0.080 ENSMUST00000098143.4
ENSMUST00000030133.8
ENSMUST00000091614.6
 Nfx1


nuclear transcription factor, X-box binding 1


chr7_+_44496588 0.076 ENSMUST00000107927.3
 Fam71e1
family with sequence similarity 71, member E1
chr14_+_20694956 0.076 ENSMUST00000048016.1
 Fut11
fucosyltransferase 11
chr8_-_123949201 0.076 ENSMUST00000044795.7
 Nup133
nucleoporin 133
chr11_-_74724670 0.076 ENSMUST00000021091.8
 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr7_-_111082997 0.074 ENSMUST00000161051.1
ENSMUST00000160132.1
ENSMUST00000106666.3
ENSMUST00000162415.1
 Eif4g2



eukaryotic translation initiation factor 4, gamma 2



chr1_-_91459254 0.074 ENSMUST00000069620.8
 Per2
period circadian clock 2
chr9_-_48495321 0.073 ENSMUST00000170000.2
 Rbm7
RNA binding motif protein 7
chr19_-_41981119 0.070 ENSMUST00000026168.2
ENSMUST00000171561.1
 Mms19

MMS19 (MET18 S. cerevisiae)

chr15_-_81400043 0.068 ENSMUST00000172107.1
ENSMUST00000169204.1
ENSMUST00000163382.1
 St13


suppression of tumorigenicity 13


chr7_+_101663633 0.067 ENSMUST00000001884.7
 Clpb
ClpB caseinolytic peptidase B
chr6_+_29348069 0.067 ENSMUST00000173216.1
ENSMUST00000031779.10
ENSMUST00000090481.7
 Calu


calumenin


chr7_+_100607410 0.062 ENSMUST00000107048.1
ENSMUST00000032946.3
 Rab6a

RAB6A, member RAS oncogene family

chr3_+_138143429 0.061 ENSMUST00000040321.6
 Trmt10a
tRNA methyltransferase 10A
chr6_-_87672142 0.058 ENSMUST00000032130.2
ENSMUST00000065997.2
 Aplf

aprataxin and PNKP like factor

chr17_+_85090647 0.051 ENSMUST00000095188.5
 Camkmt
calmodulin-lysine N-methyltransferase
chr11_-_86544754 0.045 ENSMUST00000138810.1
ENSMUST00000058286.2
ENSMUST00000154617.1
 Rps6kb1


ribosomal protein S6 kinase, polypeptide 1


chr19_+_46075842 0.044 ENSMUST00000165017.1
 Nolc1
nucleolar and coiled-body phosphoprotein 1
chr1_-_160212864 0.044 ENSMUST00000014370.5
 Cacybp
calcyclin binding protein
chr19_-_44135816 0.044 ENSMUST00000026218.5
 Cwf19l1
CWF19-like 1, cell cycle control (S. pombe)
chr8_-_94918012 0.042 ENSMUST00000077955.5
 Ccdc102a
coiled-coil domain containing 102A
chr16_+_49699198 0.042 ENSMUST00000046777.4
ENSMUST00000142682.1
 Ift57

intraflagellar transport 57

chr4_-_126202757 0.039 ENSMUST00000080919.5
 Thrap3
thyroid hormone receptor associated protein 3
chr3_-_19311269 0.035 ENSMUST00000099195.3
 Pde7a
phosphodiesterase 7A
chr5_-_122779278 0.034 ENSMUST00000111668.3
 Camkk2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr10_-_112928974 0.030 ENSMUST00000099276.2
 Atxn7l3b
ataxin 7-like 3B
chrX_+_150588223 0.027 ENSMUST00000153221.1
 Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr15_+_102073773 0.025 ENSMUST00000169681.1
 Eif4b
eukaryotic translation initiation factor 4B
chr17_-_56626872 0.024 ENSMUST00000047226.8
 Lonp1
lon peptidase 1, mitochondrial
chr7_+_35397046 0.018 ENSMUST00000079414.5
 Cep89
centrosomal protein 89
chr19_-_40588453 0.015 ENSMUST00000025979.6
 Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr19_-_40588338 0.014 ENSMUST00000176939.1
 Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr15_-_79546741 0.005 ENSMUST00000054014.7
 Ddx17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr7_+_100607660 0.005 ENSMUST00000098252.4
 Rab6a
RAB6A, member RAS oncogene family
chr7_-_19310035 0.002 ENSMUST00000003640.2
 Fosb
FBJ osteosarcoma oncogene B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.2 0.5 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.1 0.4 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 0.2 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.3 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.2 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.0 0.2 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.3 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661) regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.5 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 0.6 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.2 GO:0032564 dATP binding(GO:0032564)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0070182 DNA polymerase binding(GO:0070182)