Motif ID: Gmeb2

Z-value: 0.753


Transcription factors associated with Gmeb2:

Gene SymbolEntrez IDGene Name
Gmeb2 ENSMUSG00000038705.7 Gmeb2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gmeb2mm10_v2_chr2_-_181288016_1812880410.175.6e-01Click!


Activity profile for motif Gmeb2.

activity profile for motif Gmeb2


Sorted Z-values histogram for motif Gmeb2

Sorted Z-values for motif Gmeb2



Network of associatons between targets according to the STRING database.



First level regulatory network of Gmeb2

PNG image of the network

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Top targets:


Showing 1 to 20 of 180 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_119896285 1.633 ENSMUST00000106519.1
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr7_+_66839726 1.606 ENSMUST00000098382.3
Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr7_+_66839752 1.525 ENSMUST00000107478.1
Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr15_-_78544345 1.496 ENSMUST00000053239.2
Sstr3
somatostatin receptor 3
chr11_-_107348130 1.459 ENSMUST00000134763.1
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr7_-_119895697 1.442 ENSMUST00000059851.6
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr4_+_102570065 1.326 ENSMUST00000097950.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr7_-_119895446 1.293 ENSMUST00000098080.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr6_-_39725193 1.266 ENSMUST00000101497.3
Braf
Braf transforming gene
chr1_+_185454803 1.248 ENSMUST00000061093.6
Slc30a10
solute carrier family 30, member 10
chr17_-_94749874 1.237 ENSMUST00000171284.1
Mettl4
methyltransferase like 4
chr1_-_162740350 1.225 ENSMUST00000182331.1
ENSMUST00000183011.1
ENSMUST00000182593.1
ENSMUST00000182149.1
Prrc2c



proline-rich coiled-coil 2C



chr1_-_161034794 1.072 ENSMUST00000177003.1
ENSMUST00000162226.2
ENSMUST00000159250.2
Zbtb37


zinc finger and BTB domain containing 37


chr1_-_162740540 1.003 ENSMUST00000028016.9
ENSMUST00000182660.1
Prrc2c

proline-rich coiled-coil 2C

chr4_-_149307506 0.967 ENSMUST00000055647.8
ENSMUST00000030806.5
ENSMUST00000060537.6
Kif1b


kinesin family member 1B


chr16_+_14361552 0.860 ENSMUST00000100167.3
ENSMUST00000154748.1
ENSMUST00000134776.1
Abcc1


ATP-binding cassette, sub-family C (CFTR/MRP), member 1


chr9_+_46012822 0.858 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3

SIK family kinase 3

chr17_-_85090204 0.814 ENSMUST00000072406.3
ENSMUST00000171795.1
Prepl

prolyl endopeptidase-like

chr5_-_110343009 0.750 ENSMUST00000058016.9
ENSMUST00000112478.3
P2rx2

purinergic receptor P2X, ligand-gated ion channel, 2

chr12_+_73964481 0.742 ENSMUST00000021532.4
Snapc1
small nuclear RNA activating complex, polypeptide 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 4.4 GO:0010225 response to UV-C(GO:0010225)
0.1 1.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 1.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 1.3 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 1.3 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 1.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 1.2 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 1.0 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.3 0.9 GO:0042939 glutathione transport(GO:0034635) oligopeptide transmembrane transport(GO:0035672) xenobiotic transport(GO:0042908) tripeptide transport(GO:0042939)
0.0 0.9 GO:0035904 aorta development(GO:0035904)
0.0 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.2 0.7 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.2 0.7 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.7 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.1 0.6 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.6 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.6 GO:0051646 mitochondrion localization(GO:0051646)
0.2 0.5 GO:0002842 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
0.2 0.5 GO:0019401 alditol biosynthetic process(GO:0019401)
0.1 0.5 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.6 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 1.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.6 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.6 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.4 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.1 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.9 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.5 1.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 1.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.3 GO:0046870 cadmium ion binding(GO:0046870)
0.0 1.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 1.3 GO:0030552 cAMP binding(GO:0030552)
0.3 0.9 GO:0015562 efflux transmembrane transporter activity(GO:0015562) oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.8 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 0.7 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.6 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.5 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.1 0.5 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 0.5 GO:0043559 insulin binding(GO:0043559)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.4 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)