Motif ID: Grhl1

Z-value: 0.511


Transcription factors associated with Grhl1:

Gene SymbolEntrez IDGene Name
Grhl1 ENSMUSG00000020656.9 Grhl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Grhl1mm10_v2_chr12_+_24572276_24572308-0.039.3e-01Click!


Activity profile for motif Grhl1.

activity profile for motif Grhl1


Sorted Z-values histogram for motif Grhl1

Sorted Z-values for motif Grhl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Grhl1

PNG image of the network

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Top targets:


Showing 1 to 20 of 50 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_87263518 1.828 ENSMUST00000090986.4
 Fcrls
Fc receptor-like S, scavenger receptor
chr14_-_57133268 1.128 ENSMUST00000160703.1
 Gjb6
gap junction protein, beta 6
chr3_-_87263703 1.082 ENSMUST00000146512.1
 Fcrls
Fc receptor-like S, scavenger receptor
chr18_+_56432116 0.950 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr14_+_75136326 0.899 ENSMUST00000145303.1
 Lcp1
lymphocyte cytosolic protein 1
chrX_+_100730178 0.740 ENSMUST00000113744.1
 Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr9_-_44268156 0.600 ENSMUST00000169651.1
 Nlrx1
NLR family member X1
chr1_-_192855723 0.585 ENSMUST00000155579.1
 Sertad4
SERTA domain containing 4
chr8_+_80494032 0.564 ENSMUST00000063359.6
 Gypa
glycophorin A
chr4_+_141242850 0.523 ENSMUST00000138096.1
ENSMUST00000006618.2
ENSMUST00000125392.1
 Arhgef19


Rho guanine nucleotide exchange factor (GEF) 19


chr2_-_30205772 0.501 ENSMUST00000113662.1
 Ccbl1
cysteine conjugate-beta lyase 1
chr9_+_15239045 0.488 ENSMUST00000034413.6
 Vstm5
V-set and transmembrane domain containing 5
chr17_+_87635974 0.483 ENSMUST00000053577.8
 Epcam
epithelial cell adhesion molecule
chr2_-_30205794 0.464 ENSMUST00000113663.2
ENSMUST00000044038.3
 Ccbl1

cysteine conjugate-beta lyase 1

chr4_+_155086577 0.449 ENSMUST00000030915.4
ENSMUST00000155775.1
ENSMUST00000127457.1
 Morn1


MORN repeat containing 1


chr8_-_71381907 0.400 ENSMUST00000002466.8
 Nr2f6
nuclear receptor subfamily 2, group F, member 6
chr12_+_76417598 0.378 ENSMUST00000063977.7
 Ppp1r36
protein phosphatase 1, regulatory subunit 36
chr17_+_43389436 0.351 ENSMUST00000113599.1
 Gpr116
G protein-coupled receptor 116
chr14_+_63943666 0.346 ENSMUST00000079652.5
 Sox7
SRY-box containing gene 7
chr14_-_73385225 0.332 ENSMUST00000022704.7
 Itm2b
integral membrane protein 2B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.7 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.6 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.6 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.4 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782) positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.1 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0005922 connexon complex(GO:0005922)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891) podosome(GO:0002102)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.0 GO:0031088 platelet dense granule membrane(GO:0031088)

Gene overrepresentation in molecular_function category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.2 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.1 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)