Motif ID: Grhl1

Z-value: 0.511


Transcription factors associated with Grhl1:

Gene SymbolEntrez IDGene Name
Grhl1 ENSMUSG00000020656.9 Grhl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Grhl1mm10_v2_chr12_+_24572276_24572308-0.039.3e-01Click!


Activity profile for motif Grhl1.

activity profile for motif Grhl1


Sorted Z-values histogram for motif Grhl1

Sorted Z-values for motif Grhl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Grhl1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_87263518 1.828 ENSMUST00000090986.4
Fcrls
Fc receptor-like S, scavenger receptor
chr14_-_57133268 1.128 ENSMUST00000160703.1
Gjb6
gap junction protein, beta 6
chr3_-_87263703 1.082 ENSMUST00000146512.1
Fcrls
Fc receptor-like S, scavenger receptor
chr18_+_56432116 0.950 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr14_+_75136326 0.899 ENSMUST00000145303.1
Lcp1
lymphocyte cytosolic protein 1
chrX_+_100730178 0.740 ENSMUST00000113744.1
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr9_-_44268156 0.600 ENSMUST00000169651.1
Nlrx1
NLR family member X1
chr1_-_192855723 0.585 ENSMUST00000155579.1
Sertad4
SERTA domain containing 4
chr8_+_80494032 0.564 ENSMUST00000063359.6
Gypa
glycophorin A
chr4_+_141242850 0.523 ENSMUST00000138096.1
ENSMUST00000006618.2
ENSMUST00000125392.1
Arhgef19


Rho guanine nucleotide exchange factor (GEF) 19


chr2_-_30205772 0.501 ENSMUST00000113662.1
Ccbl1
cysteine conjugate-beta lyase 1
chr9_+_15239045 0.488 ENSMUST00000034413.6
Vstm5
V-set and transmembrane domain containing 5
chr17_+_87635974 0.483 ENSMUST00000053577.8
Epcam
epithelial cell adhesion molecule
chr2_-_30205794 0.464 ENSMUST00000113663.2
ENSMUST00000044038.3
Ccbl1

cysteine conjugate-beta lyase 1

chr4_+_155086577 0.449 ENSMUST00000030915.4
ENSMUST00000155775.1
ENSMUST00000127457.1
Morn1


MORN repeat containing 1


chr8_-_71381907 0.400 ENSMUST00000002466.8
Nr2f6
nuclear receptor subfamily 2, group F, member 6
chr12_+_76417598 0.378 ENSMUST00000063977.7
Ppp1r36
protein phosphatase 1, regulatory subunit 36
chr17_+_43389436 0.351 ENSMUST00000113599.1
Gpr116
G protein-coupled receptor 116
chr14_+_63943666 0.346 ENSMUST00000079652.5
Sox7
SRY-box containing gene 7
chr14_-_73385225 0.332 ENSMUST00000022704.7
Itm2b
integral membrane protein 2B
chr9_+_21337828 0.325 ENSMUST00000034697.7
Slc44a2
solute carrier family 44, member 2
chr19_-_18631754 0.316 ENSMUST00000025631.6
Ostf1
osteoclast stimulating factor 1
chr12_+_90738201 0.254 ENSMUST00000181874.1
Gm26512
predicted gene, 26512
chr7_+_101321703 0.248 ENSMUST00000174291.1
ENSMUST00000167888.2
ENSMUST00000172662.1
ENSMUST00000173270.1
ENSMUST00000174083.1
Stard10




START domain containing 10




chr10_+_128747850 0.243 ENSMUST00000163377.2
Wibg
within bgcn homolog (Drosophila)
chr4_+_108834601 0.218 ENSMUST00000030296.8
Txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr14_+_79481164 0.206 ENSMUST00000040131.5
Elf1
E74-like factor 1
chr12_-_54656496 0.197 ENSMUST00000056228.6
Sptssa
serine palmitoyltransferase, small subunit A
chr4_-_155086271 0.188 ENSMUST00000030914.3
Rer1
RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)
chr7_+_65693417 0.179 ENSMUST00000032726.7
ENSMUST00000107495.3
Tm2d3

TM2 domain containing 3

chr5_-_137600650 0.174 ENSMUST00000111007.1
ENSMUST00000133705.1
Mospd3

motile sperm domain containing 3

chr9_-_7872983 0.146 ENSMUST00000115672.1
Birc3
baculoviral IAP repeat-containing 3
chr6_+_128438757 0.140 ENSMUST00000144745.1
Gm10069
predicted gene 10069
chr3_-_85722474 0.135 ENSMUST00000119077.1
Fam160a1
family with sequence similarity 160, member A1
chr17_+_29268788 0.132 ENSMUST00000064709.5
ENSMUST00000120346.1
BC004004

cDNA sequence BC004004

chr1_+_135818593 0.107 ENSMUST00000038760.8
Lad1
ladinin
chr4_+_109676568 0.106 ENSMUST00000102724.4
Faf1
Fas-associated factor 1
chr17_-_56005566 0.098 ENSMUST00000043785.6
Stap2
signal transducing adaptor family member 2
chr19_+_18631927 0.077 ENSMUST00000159572.1
ENSMUST00000042392.7
Nmrk1

nicotinamide riboside kinase 1

chr10_-_79533750 0.076 ENSMUST00000166804.1
ENSMUST00000063879.5
Ppap2c

phosphatidic acid phosphatase type 2C

chr18_-_25753852 0.075 ENSMUST00000025117.6
ENSMUST00000115816.2
Celf4

CUGBP, Elav-like family member 4

chr2_-_30967859 0.074 ENSMUST00000028200.8
Tor1a
torsin family 1, member A (torsin A)
chr4_-_19570073 0.074 ENSMUST00000029885.4
Cpne3
copine III
chr17_-_34628005 0.073 ENSMUST00000166040.2
Ppt2
palmitoyl-protein thioesterase 2
chrX_-_38456407 0.048 ENSMUST00000074913.5
ENSMUST00000016678.7
ENSMUST00000061755.8
Lamp2


lysosomal-associated membrane protein 2


chr2_-_151973387 0.042 ENSMUST00000109863.1
Fam110a
family with sequence similarity 110, member A
chr17_+_56005672 0.035 ENSMUST00000133998.1
Mpnd
MPN domain containing
chr7_+_65693447 0.033 ENSMUST00000143508.1
Tm2d3
TM2 domain containing 3
chr8_-_95853501 0.020 ENSMUST00000040481.3
Slc38a7
solute carrier family 38, member 7
chr16_-_26989974 0.016 ENSMUST00000089832.4
Gmnc
geminin coiled-coil domain containing

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.6 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.7 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782) positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.4 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0005922 connexon complex(GO:0005922)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891) podosome(GO:0002102)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.2 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.1 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.1 0.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)