Motif ID: Gsc2_Dmbx1

Z-value: 0.706

Transcription factors associated with Gsc2_Dmbx1:

Gene SymbolEntrez IDGene Name
Dmbx1 ENSMUSG00000028707.9 Dmbx1
Gsc2 ENSMUSG00000022738.6 Gsc2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dmbx1mm10_v2_chr4_-_115939923_115939928-0.136.6e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gsc2_Dmbx1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_93595877 3.702 ENSMUST00000048982.4
Prickle1
prickle homolog 1 (Drosophila)
chr3_-_103737995 2.456 ENSMUST00000029440.8
Olfml3
olfactomedin-like 3
chr7_-_133015248 1.174 ENSMUST00000169570.1
Ctbp2
C-terminal binding protein 2
chr8_-_113848615 1.092 ENSMUST00000093113.4
Adamts18
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
chr11_-_70459957 0.966 ENSMUST00000019064.2
Cxcl16
chemokine (C-X-C motif) ligand 16
chr4_+_102589687 0.892 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr11_-_107337556 0.807 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr5_+_77265454 0.765 ENSMUST00000080359.5
Rest
RE1-silencing transcription factor
chr10_-_6980376 0.736 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr15_+_4375462 0.709 ENSMUST00000061925.4
Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr6_-_124840192 0.700 ENSMUST00000024206.5
Gnb3
guanine nucleotide binding protein (G protein), beta 3
chrX_+_74424632 0.674 ENSMUST00000114129.2
ENSMUST00000132749.1
Ikbkg

inhibitor of kappaB kinase gamma

chr14_-_118052235 0.643 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr1_+_12692430 0.543 ENSMUST00000180062.1
ENSMUST00000177608.1
Sulf1

sulfatase 1

chr1_-_168431695 0.501 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr16_-_46010212 0.480 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr17_+_27655572 0.451 ENSMUST00000045896.3
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr17_+_35861343 0.450 ENSMUST00000172931.1
Nrm
nurim (nuclear envelope membrane protein)
chr7_-_80403315 0.438 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr4_-_141053660 0.429 ENSMUST00000040222.7
Crocc
ciliary rootlet coiled-coil, rootletin
chr17_+_27655509 0.428 ENSMUST00000114873.1
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr5_-_144223516 0.421 ENSMUST00000085701.6
Tecpr1
tectonin beta-propeller repeat containing 1
chr17_+_27655643 0.403 ENSMUST00000114872.1
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr1_-_168431502 0.398 ENSMUST00000064438.4
Pbx1
pre B cell leukemia homeobox 1
chr11_+_113659283 0.392 ENSMUST00000137878.1
Cog1
component of oligomeric golgi complex 1
chr14_-_19977040 0.392 ENSMUST00000159028.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr2_+_102659213 0.376 ENSMUST00000111213.1
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr10_-_22149270 0.370 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chrX_-_43167817 0.363 ENSMUST00000115058.1
ENSMUST00000115059.1
Tenm1

teneurin transmembrane protein 1

chr11_-_68973840 0.350 ENSMUST00000038644.4
Rangrf
RAN guanine nucleotide release factor
chr14_-_19977151 0.337 ENSMUST00000055100.7
ENSMUST00000162425.1
Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr8_+_78509319 0.318 ENSMUST00000034111.8
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr14_-_31640878 0.313 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
Hacl1


2-hydroxyacyl-CoA lyase 1


chr1_+_178187721 0.307 ENSMUST00000159284.1
Desi2
desumoylating isopeptidase 2
chr17_+_35861318 0.269 ENSMUST00000074259.8
ENSMUST00000174873.1
Nrm

nurim (nuclear envelope membrane protein)

chr2_+_91259822 0.246 ENSMUST00000138470.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr10_+_18407658 0.237 ENSMUST00000037341.7
Nhsl1
NHS-like 1
chr6_-_59426279 0.232 ENSMUST00000051065.4
Gprin3
GPRIN family member 3
chr1_+_44551650 0.211 ENSMUST00000160854.1
Gulp1
GULP, engulfment adaptor PTB domain containing 1
chr11_+_70459940 0.208 ENSMUST00000147289.1
ENSMUST00000126105.1
Zmynd15

zinc finger, MYND-type containing 15

chr13_+_23752267 0.193 ENSMUST00000091703.2
Hist1h3b
histone cluster 1, H3b
chr5_+_3343893 0.186 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr5_-_134456702 0.185 ENSMUST00000073161.5
ENSMUST00000171794.2
ENSMUST00000111245.2
ENSMUST00000100654.3
ENSMUST00000167084.2
ENSMUST00000100652.3
ENSMUST00000100650.3
ENSMUST00000074114.5
Gtf2ird1







general transcription factor II I repeat domain-containing 1







chrX_+_74424534 0.173 ENSMUST00000135165.1
ENSMUST00000114128.1
ENSMUST00000114133.2
ENSMUST00000004330.3
Ikbkg



inhibitor of kappaB kinase gamma



chr19_-_43752924 0.172 ENSMUST00000045562.5
Cox15
cytochrome c oxidase assembly protein 15
chr19_+_26605106 0.159 ENSMUST00000025862.7
ENSMUST00000176030.1
Smarca2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr1_-_168431896 0.152 ENSMUST00000176540.1
Pbx1
pre B cell leukemia homeobox 1
chr11_-_103954015 0.151 ENSMUST00000103075.4
Nsf
N-ethylmaleimide sensitive fusion protein
chr13_-_23562369 0.149 ENSMUST00000105107.1
Hist1h3e
histone cluster 1, H3e
chr14_-_19977249 0.144 ENSMUST00000160013.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr4_-_129742275 0.142 ENSMUST00000066257.5
Khdrbs1
KH domain containing, RNA binding, signal transduction associated 1
chr5_+_149184678 0.142 ENSMUST00000139474.1
ENSMUST00000117878.1
Uspl1

ubiquitin specific peptidase like 1

chr2_-_30093607 0.138 ENSMUST00000081838.6
Zdhhc12
zinc finger, DHHC domain containing 12
chr11_-_59187738 0.130 ENSMUST00000170895.2
Guk1
guanylate kinase 1
chr7_+_13398115 0.122 ENSMUST00000005791.7
Cabp5
calcium binding protein 5
chr18_+_46597698 0.119 ENSMUST00000078079.3
ENSMUST00000168382.1
Eif1a

eukaryotic translation initiation factor 1A

chr6_+_136954521 0.113 ENSMUST00000137768.1
Pde6h
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr7_-_25398697 0.111 ENSMUST00000105177.2
ENSMUST00000149349.1
Lipe

lipase, hormone sensitive

chr4_-_141053704 0.111 ENSMUST00000102491.3
Crocc
ciliary rootlet coiled-coil, rootletin
chr3_+_28781305 0.110 ENSMUST00000060500.7
Eif5a2
eukaryotic translation initiation factor 5A2
chr6_+_4902913 0.107 ENSMUST00000175889.1
ENSMUST00000168998.2
Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr11_+_70017085 0.094 ENSMUST00000108589.2
Dlg4
discs, large homolog 4 (Drosophila)
chr8_+_19682268 0.091 ENSMUST00000153710.1
ENSMUST00000127799.1
Gm6483

predicted gene 6483

chr11_+_19924403 0.088 ENSMUST00000093298.5
Spred2
sprouty-related, EVH1 domain containing 2
chr18_-_12305638 0.081 ENSMUST00000122408.1
ENSMUST00000118525.1
ENSMUST00000142066.1
Ankrd29


ankyrin repeat domain 29


chr11_+_109649376 0.080 ENSMUST00000106677.1
Prkar1a
protein kinase, cAMP dependent regulatory, type I, alpha
chr2_-_30093642 0.079 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr11_-_5099084 0.076 ENSMUST00000063232.6
Ewsr1
Ewing sarcoma breakpoint region 1
chr9_-_60838200 0.075 ENSMUST00000063858.7
Gm9869
predicted gene 9869
chr2_-_73486456 0.074 ENSMUST00000141264.1
Wipf1
WAS/WASL interacting protein family, member 1
chr10_+_80930071 0.073 ENSMUST00000015456.8
Gadd45b
growth arrest and DNA-damage-inducible 45 beta
chr1_-_155232710 0.063 ENSMUST00000035914.3
BC034090
cDNA sequence BC034090
chr11_-_5099223 0.060 ENSMUST00000079949.6
Ewsr1
Ewing sarcoma breakpoint region 1
chr11_-_5099036 0.053 ENSMUST00000102930.3
Ewsr1
Ewing sarcoma breakpoint region 1
chr16_-_4213404 0.053 ENSMUST00000023165.6
Crebbp
CREB binding protein
chr11_+_70017199 0.042 ENSMUST00000133140.1
Dlg4
discs, large homolog 4 (Drosophila)
chr7_-_105752193 0.042 ENSMUST00000033184.4
Tpp1
tripeptidyl peptidase I
chr8_-_60954726 0.036 ENSMUST00000110302.1
Clcn3
chloride channel 3
chr11_+_23256566 0.034 ENSMUST00000136235.1
Xpo1
exportin 1, CRM1 homolog (yeast)
chr11_-_5099053 0.032 ENSMUST00000093365.5
ENSMUST00000073308.4
Ewsr1

Ewing sarcoma breakpoint region 1

chr1_-_44218952 0.031 ENSMUST00000054801.3
Mettl21e
methyltransferase like 21E
chr11_+_5099608 0.031 ENSMUST00000139742.1
Rhbdd3
rhomboid domain containing 3
chr2_+_164562579 0.030 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr4_-_133968611 0.029 ENSMUST00000102552.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr14_-_54617993 0.028 ENSMUST00000022803.4
Psmb5
proteasome (prosome, macropain) subunit, beta type 5
chr11_-_90687572 0.025 ENSMUST00000107869.2
ENSMUST00000154599.1
ENSMUST00000107868.1
ENSMUST00000020849.2
Tom1l1



target of myb1-like 1 (chicken)



chr7_+_126976338 0.022 ENSMUST00000032920.3
Cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr1_+_178187417 0.014 ENSMUST00000161075.1
ENSMUST00000027783.7
Desi2

desumoylating isopeptidase 2

chr13_-_21783391 0.003 ENSMUST00000099704.3
Hist1h3i
histone cluster 1, H3i
chr19_+_46056539 0.003 ENSMUST00000111899.1
ENSMUST00000099392.3
ENSMUST00000062322.4
Pprc1


peroxisome proliferative activated receptor, gamma, coactivator-related 1


chr4_-_137766474 0.000 ENSMUST00000139951.1
Alpl
alkaline phosphatase, liver/bone/kidney
chrX_+_48623737 0.000 ENSMUST00000114936.1
Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.2 0.8 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.2 0.5 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.6 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 1.0 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.4 GO:0032911 nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 1.1 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 1.0 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 0.9 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 1.5 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.2 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.1 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0009182 purine deoxyribonucleotide biosynthetic process(GO:0009153) purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) GDP metabolic process(GO:0046710)
0.0 1.1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.3 GO:2000010 positive regulation of protein localization to cell surface(GO:2000010)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.4 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.4 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388) synaptic vesicle lumen acidification(GO:0097401)
0.0 0.2 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.0 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.7 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 3.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.0 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 0.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.8 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.0 0.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 1.0 GO:0030552 cAMP binding(GO:0030552)
0.0 1.0 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.2 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 1.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 0.0 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.1 GO:0030553 cGMP binding(GO:0030553) 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)