Motif ID: Hcfc1_Six5_Smarcc2_Zfp143

Z-value: 1.742

Transcription factors associated with Hcfc1_Six5_Smarcc2_Zfp143:

Gene SymbolEntrez IDGene Name
Hcfc1 ENSMUSG00000031386.8 Hcfc1
Six5 ENSMUSG00000040841.5 Six5
Smarcc2 ENSMUSG00000025369.8 Smarcc2
Zfp143 ENSMUSG00000061079.7 Zfp143

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp143mm10_v2_chr7_+_110061702_1100617320.554.3e-02Click!
Six5mm10_v2_chr7_+_19094594_19094633-0.322.6e-01Click!
Smarcc2mm10_v2_chr10_+_128459236_1284592480.302.9e-01Click!
Hcfc1mm10_v2_chrX_-_73966329_739663760.263.8e-01Click!


Activity profile for motif Hcfc1_Six5_Smarcc2_Zfp143.

activity profile for motif Hcfc1_Six5_Smarcc2_Zfp143


Sorted Z-values histogram for motif Hcfc1_Six5_Smarcc2_Zfp143

Sorted Z-values for motif Hcfc1_Six5_Smarcc2_Zfp143



Network of associatons between targets according to the STRING database.



First level regulatory network of Hcfc1_Six5_Smarcc2_Zfp143

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_151996113 2.806 ENSMUST00000055688.9
 Phf13
PHD finger protein 13
chr7_+_97332311 1.929 ENSMUST00000054107.5
 Kctd21
potassium channel tetramerisation domain containing 21
chr7_-_29518566 1.929 ENSMUST00000181975.1
 Sipa1l3
signal-induced proliferation-associated 1 like 3
chr9_-_72985344 1.824 ENSMUST00000124565.2
 Gm5918
predicted gene 5918
chr7_+_29768552 1.796 ENSMUST00000032802.4
 Zfp84
zinc finger protein 84
chr7_+_19119853 1.765 ENSMUST00000053109.3
 Fbxo46
F-box protein 46
chr14_+_64950037 1.748 ENSMUST00000043914.5
 Ints9
integrator complex subunit 9
chr1_-_134955847 1.744 ENSMUST00000168381.1
 Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr4_+_134396320 1.677 ENSMUST00000105869.2
 Pafah2
platelet-activating factor acetylhydrolase 2
chr1_+_151428612 1.494 ENSMUST00000065625.5
 Trmt1l
tRNA methyltransferase 1 like
chr4_-_116708312 1.475 ENSMUST00000030453.4
 Mmachc
methylmalonic aciduria cblC type, with homocystinuria
chr7_+_12897800 1.403 ENSMUST00000055528.4
ENSMUST00000117189.1
ENSMUST00000120809.1
ENSMUST00000119989.1
 Zscan22



zinc finger and SCAN domain containing 22



chr15_-_53902472 1.348 ENSMUST00000078673.6
 Samd12
sterile alpha motif domain containing 12
chr5_-_33657889 1.343 ENSMUST00000019439.7
 Tmem129
transmembrane protein 129
chr9_+_83548309 1.333 ENSMUST00000113215.3
 Sh3bgrl2
SH3 domain binding glutamic acid-rich protein like 2
chr15_-_81729864 1.332 ENSMUST00000171115.1
ENSMUST00000170134.1
ENSMUST00000052374.5
 Rangap1


RAN GTPase activating protein 1


chr1_+_178187721 1.291 ENSMUST00000159284.1
 Desi2
desumoylating isopeptidase 2
chr15_-_44428303 1.261 ENSMUST00000038719.6
 Nudcd1
NudC domain containing 1
chr5_+_24423805 1.235 ENSMUST00000153274.1
 Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr5_+_24423851 1.225 ENSMUST00000141966.1
 Slc4a2
solute carrier family 4 (anion exchanger), member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 286 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0006821 chloride transport(GO:0006821)
0.5 2.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 2.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 2.1 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 2.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.7 2.0 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 2.0 GO:0016579 protein deubiquitination(GO:0016579)
0.3 1.9 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 1.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.6 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 1.6 GO:0016180 snRNA processing(GO:0016180)
0.0 1.6 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 1.5 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 1.5 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 1.4 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 1.4 GO:0098792 xenophagy(GO:0098792)
0.2 1.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 1.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 138 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.2 GO:0031672 A band(GO:0031672)
0.1 2.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.6 GO:0070822 Sin3-type complex(GO:0070822)
0.0 2.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.3 GO:0005840 ribosome(GO:0005840)
0.1 2.0 GO:0071565 nBAF complex(GO:0071565)
0.3 1.9 GO:0061689 tricellular tight junction(GO:0061689)
0.1 1.9 GO:0032039 integrator complex(GO:0032039)
0.1 1.8 GO:0071203 WASH complex(GO:0071203)
0.2 1.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 1.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 1.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 1.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 1.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.4 1.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 1.3 GO:0005923 bicellular tight junction(GO:0005923)
0.2 1.2 GO:0097361 CIA complex(GO:0097361)
0.0 1.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.1 GO:0035869 ciliary transition zone(GO:0035869)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 178 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 3.8 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 3.6 GO:0003774 motor activity(GO:0003774)
0.0 3.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 3.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 2.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 2.5 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 2.4 GO:0008242 omega peptidase activity(GO:0008242)
0.0 2.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 2.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 1.9 GO:0031419 cobalamin binding(GO:0031419)
0.0 1.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 1.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.2 1.7 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 1.5 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2 1.4 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.1 1.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.3 GO:0008565 protein transporter activity(GO:0008565)