Motif ID: Hdx

Z-value: 9.112


Transcription factors associated with Hdx:

Gene SymbolEntrez IDGene Name
Hdx ENSMUSG00000034551.6 Hdx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hdxmm10_v2_chrX_-_111697069_111697127-0.156.2e-01Click!


Activity profile for motif Hdx.

activity profile for motif Hdx


Sorted Z-values histogram for motif Hdx

Sorted Z-values for motif Hdx



Network of associatons between targets according to the STRING database.



First level regulatory network of Hdx

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_3017408 228.028 ENSMUST00000099049.3
Gm10719
predicted gene 10719
chr9_+_3015654 190.545 ENSMUST00000099050.3
Gm10720
predicted gene 10720
chr9_+_3023547 190.542 ENSMUST00000099046.3
Gm10718
predicted gene 10718
chr9_+_3000922 170.076 ENSMUST00000151376.2
Gm10722
predicted gene 10722
chr9_+_3027439 163.958 ENSMUST00000177875.1
ENSMUST00000179982.1
Gm10717

predicted gene 10717

chr9_+_3005125 159.182 ENSMUST00000179881.1
Gm11168
predicted gene 11168
chr9_+_3034599 148.490 ENSMUST00000178641.1
Gm17535
predicted gene, 17535
chr9_+_3025417 134.312 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr14_-_19418930 126.350 ENSMUST00000177817.1
Gm21738
predicted gene, 21738
chr9_+_3018753 101.117 ENSMUST00000179272.1
Gm10719
predicted gene 10719
chr9_+_3036877 97.522 ENSMUST00000155807.2
Gm10715
predicted gene 10715
chr9_+_3004457 95.355 ENSMUST00000178348.1
Gm11168
predicted gene 11168
chr9_+_3037111 94.166 ENSMUST00000177969.1
Gm10715
predicted gene 10715
chr9_+_3013140 92.148 ENSMUST00000143083.2
Gm10721
predicted gene 10721
chr2_-_98667264 73.610 ENSMUST00000099683.1
Gm10800
predicted gene 10800
chr7_+_13398115 6.112 ENSMUST00000005791.7
Cabp5
calcium binding protein 5
chr1_-_140183404 5.047 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr6_-_131313827 4.911 ENSMUST00000049150.1
Styk1
serine/threonine/tyrosine kinase 1
chr3_-_20242173 4.263 ENSMUST00000001921.1
Cpa3
carboxypeptidase A3, mast cell
chr8_+_66697404 4.113 ENSMUST00000039303.5
Npy1r
neuropeptide Y receptor Y1
chr7_+_19359740 3.739 ENSMUST00000140836.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr17_+_22689771 3.683 ENSMUST00000055305.8
Gm9805
predicted gene 9805
chr9_-_121495678 3.466 ENSMUST00000035120.4
Cck
cholecystokinin
chr3_-_54915867 3.230 ENSMUST00000070342.3
Sertm1
serine rich and transmembrane domain containing 1
chr4_-_149126688 2.450 ENSMUST00000030815.2
Cort
cortistatin
chr1_-_140183283 2.428 ENSMUST00000111977.1
Cfh
complement component factor h
chr11_-_28584260 2.005 ENSMUST00000093253.3
ENSMUST00000109502.2
ENSMUST00000042534.8
Ccdc85a


coiled-coil domain containing 85A


chr6_+_114131229 1.721 ENSMUST00000032451.7
Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr2_+_97467657 1.399 ENSMUST00000059049.7
Lrrc4c
leucine rich repeat containing 4C
chr1_+_87327044 1.362 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr19_+_12460749 1.223 ENSMUST00000081035.7
Mpeg1
macrophage expressed gene 1
chr6_-_149101506 1.162 ENSMUST00000127727.1
Dennd5b
DENN/MADD domain containing 5B
chr16_+_14705832 1.120 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr4_-_115133977 1.093 ENSMUST00000051400.7
Cyp4x1
cytochrome P450, family 4, subfamily x, polypeptide 1
chr9_-_39603635 0.846 ENSMUST00000119722.1
AW551984
expressed sequence AW551984
chr7_-_128596278 0.789 ENSMUST00000179317.1
Gm7258
predicted gene 7258
chrX_+_143518671 0.740 ENSMUST00000134402.1
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr11_-_67965631 0.730 ENSMUST00000021287.5
ENSMUST00000126766.1
Wdr16

WD repeat domain 16

chrX_+_143518576 0.438 ENSMUST00000033640.7
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr11_+_16257706 0.431 ENSMUST00000109645.2
ENSMUST00000109647.2
Vstm2a

V-set and transmembrane domain containing 2A

chr14_+_115092244 0.409 ENSMUST00000176912.1
ENSMUST00000175665.1
Gpc5

glypican 5

chr14_+_70774304 0.385 ENSMUST00000022698.7
Dok2
docking protein 2
chr1_+_87327008 0.377 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr5_-_27501362 0.357 ENSMUST00000155721.1
ENSMUST00000053257.3
Speer4b

spermatogenesis associated glutamate (E)-rich protein 4b

chr13_+_5861489 0.351 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr13_-_67729109 0.326 ENSMUST00000073157.6
Zfp71-rs1
zinc finger protein 71, related sequence
chr13_-_113663670 0.304 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr1_-_54194048 0.261 ENSMUST00000120904.1
Hecw2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr18_+_37477768 0.256 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr2_-_126618655 0.203 ENSMUST00000028838.4
Hdc
histidine decarboxylase
chr14_-_36968679 0.197 ENSMUST00000067700.6
Ccser2
coiled-coil serine rich 2
chr8_-_54718664 0.170 ENSMUST00000144711.2
ENSMUST00000093510.2
Wdr17

WD repeat domain 17

chr9_+_53771499 0.164 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chrX_-_21089229 0.163 ENSMUST00000040667.6
Zfp300
zinc finger protein 300
chr2_+_116900152 0.125 ENSMUST00000126467.1
ENSMUST00000128305.1
ENSMUST00000155323.1
D330050G23Rik


RIKEN cDNA D330050G23 gene


chr11_+_69765970 0.122 ENSMUST00000108642.1
ENSMUST00000156932.1
Zbtb4

zinc finger and BTB domain containing 4

chr11_+_95666957 0.015 ENSMUST00000125172.1
ENSMUST00000036374.5
Phb

prohibitin

chr11_+_82101836 0.002 ENSMUST00000000194.3
Ccl12
chemokine (C-C motif) ligand 12

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.6 4.3 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.4 4.1 GO:0030432 peristalsis(GO:0030432)
0.4 1.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.3 3.5 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.2 3.7 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 1.7 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 4.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 1298.7 GO:0008150 biological_process(GO:0008150)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 GO:0043203 axon hillock(GO:0043203)
0.1 1329.2 GO:0005575 cellular_component(GO:0005575)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0001851 complement component C3b binding(GO:0001851)
0.7 4.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.6 1.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.3 5.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 1.1 GO:0070330 aromatase activity(GO:0070330)
0.2 3.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 4.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1312.7 GO:0003674 molecular_function(GO:0003674)