Motif ID: Hey1_Myc_Mxi1

Z-value: 1.133

Transcription factors associated with Hey1_Myc_Mxi1:

Gene SymbolEntrez IDGene Name
Hey1 ENSMUSG00000040289.3 Hey1
Mxi1 ENSMUSG00000025025.7 Mxi1
Myc ENSMUSG00000022346.8 Myc

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hey1mm10_v2_chr3_-_8667033_86670460.771.3e-03Click!
Mycmm10_v2_chr15_+_61985377_619853970.431.2e-01Click!
Mxi1mm10_v2_chr19_+_53329413_53329478-0.421.3e-01Click!


Activity profile for motif Hey1_Myc_Mxi1.

activity profile for motif Hey1_Myc_Mxi1


Sorted Z-values histogram for motif Hey1_Myc_Mxi1

Sorted Z-values for motif Hey1_Myc_Mxi1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hey1_Myc_Mxi1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_54055650 4.598 ENSMUST00000021932.5
 Drd1a
dopamine receptor D1A
chr6_+_88724828 4.459 ENSMUST00000089449.2
 Mgll
monoglyceride lipase
chr15_-_44788016 4.374 ENSMUST00000090057.4
ENSMUST00000110269.1
 Sybu

syntabulin (syntaxin-interacting)

chr6_+_88724412 3.929 ENSMUST00000113585.2
 Mgll
monoglyceride lipase
chr9_+_34486125 3.851 ENSMUST00000115148.2
ENSMUST00000183580.1
 Kirrel3
RP24-225I21.1
kin of IRRE like 3 (Drosophila)
RP24-225I21.1
chr11_+_98348404 3.542 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr6_+_88724462 3.453 ENSMUST00000113582.1
 Mgll
monoglyceride lipase
chr2_+_129198757 3.410 ENSMUST00000028880.3
 Slc20a1
solute carrier family 20, member 1
chr15_+_44787746 3.224 ENSMUST00000181839.1
 2310069G16Rik
RIKEN cDNA 2310069G16 gene
chr7_-_68749170 2.907 ENSMUST00000118110.1
ENSMUST00000048068.7
 Arrdc4

arrestin domain containing 4

chr2_+_68861564 2.813 ENSMUST00000176018.1
 Cers6
ceramide synthase 6
chrX_+_86191764 2.721 ENSMUST00000026036.4
 Nr0b1
nuclear receptor subfamily 0, group B, member 1
chr3_+_104638658 2.699 ENSMUST00000046212.1
 Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr11_+_101316200 2.608 ENSMUST00000142640.1
ENSMUST00000019470.7
 Psme3

proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)

chr19_-_14598031 2.393 ENSMUST00000167776.2
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr19_-_14597983 2.352 ENSMUST00000052011.7
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr1_+_119526125 2.283 ENSMUST00000183952.1
 TMEM185B
Transmembrane protein 185B
chr14_-_68124836 2.236 ENSMUST00000111089.1
ENSMUST00000022638.5
 Nefm

neurofilament, medium polypeptide

chrX_-_48208566 2.225 ENSMUST00000037960.4
 Zdhhc9
zinc finger, DHHC domain containing 9
chr19_+_43440404 2.185 ENSMUST00000165311.1
 Cnnm1
cyclin M1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 429 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.2 15.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 4.7 GO:0046513 ceramide biosynthetic process(GO:0046513)
1.4 4.2 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.8 3.9 GO:0002121 inter-male aggressive behavior(GO:0002121)
1.2 3.7 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 3.3 GO:0006817 phosphate ion transport(GO:0006817)
0.6 3.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.8 3.1 GO:0010288 response to lead ion(GO:0010288)
0.3 3.0 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 3.0 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 3.0 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.3 2.9 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 2.8 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 2.8 GO:0045214 sarcomere organization(GO:0045214)
0.1 2.8 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.4 2.7 GO:0035902 response to immobilization stress(GO:0035902)
0.4 2.6 GO:0001842 neural fold formation(GO:0001842)
0.3 2.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.6 2.5 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 2.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 191 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 13.7 GO:0043196 varicosity(GO:0043196)
0.1 5.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 4.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.6 4.6 GO:0097433 dense body(GO:0097433)
0.1 3.8 GO:0043034 costamere(GO:0043034)
0.1 3.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.9 3.5 GO:0008537 proteasome activator complex(GO:0008537)
0.0 3.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 3.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 3.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 2.6 GO:0042788 polysomal ribosome(GO:0042788)
0.0 2.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.3 2.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.2 2.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 2.2 GO:0016235 aggresome(GO:0016235)
0.0 2.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 2.1 GO:0005883 neurofilament(GO:0005883)
0.0 2.1 GO:0005643 nuclear pore(GO:0005643)
0.0 1.9 GO:0005871 kinesin complex(GO:0005871)
0.1 1.8 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 272 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 15.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 5.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 5.2 GO:0051018 protein kinase A binding(GO:0051018)
0.1 4.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.5 4.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 4.0 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 3.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 3.8 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.1 3.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
1.2 3.5 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.4 3.5 GO:0061133 endopeptidase activator activity(GO:0061133)
1.1 3.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 2.9 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 2.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 2.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 2.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 2.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 2.6 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 2.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.6 GO:0008139 nuclear localization sequence binding(GO:0008139)