Motif ID: Hey2

Z-value: 1.038


Transcription factors associated with Hey2:

Gene SymbolEntrez IDGene Name
Hey2 ENSMUSG00000019789.8 Hey2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hey2mm10_v2_chr10_-_30842765_308428010.146.3e-01Click!


Activity profile for motif Hey2.

activity profile for motif Hey2


Sorted Z-values histogram for motif Hey2

Sorted Z-values for motif Hey2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hey2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_116532441 2.934 ENSMUST00000106386.1
ENSMUST00000145737.1
ENSMUST00000155102.1
ENSMUST00000063446.6
Sphk1



sphingosine kinase 1



chr7_-_66427469 2.677 ENSMUST00000015278.7
Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
chr15_+_57694651 2.422 ENSMUST00000096430.4
Zhx2
zinc fingers and homeoboxes 2
chr10_+_128909866 2.407 ENSMUST00000026407.7
Cd63
CD63 antigen
chr2_-_180104463 2.363 ENSMUST00000056480.3
Hrh3
histamine receptor H3
chr15_+_52040107 2.064 ENSMUST00000090025.4
Aard
alanine and arginine rich domain containing protein
chr7_+_35119285 1.980 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr2_-_114013619 1.898 ENSMUST00000090275.4
Gjd2
gap junction protein, delta 2
chr1_+_120340569 1.875 ENSMUST00000037286.8
C1ql2
complement component 1, q subcomponent-like 2
chr8_+_65618009 1.856 ENSMUST00000110258.1
ENSMUST00000110256.1
ENSMUST00000110255.1
March1


membrane-associated ring finger (C3HC4) 1


chr4_+_117835387 1.670 ENSMUST00000169885.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr15_-_58076456 1.616 ENSMUST00000070143.6
ENSMUST00000110168.1
Zhx1

zinc fingers and homeoboxes 1

chr8_+_119446719 1.539 ENSMUST00000098363.3
Necab2
N-terminal EF-hand calcium binding protein 2
chr16_+_33829624 1.519 ENSMUST00000115028.3
Itgb5
integrin beta 5
chr9_-_54661870 1.380 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr5_+_111733924 1.358 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr11_+_120721452 1.344 ENSMUST00000018156.5
Rac3
RAS-related C3 botulinum substrate 3
chr11_+_120721543 1.305 ENSMUST00000142229.1
Rac3
RAS-related C3 botulinum substrate 3
chr1_-_152766281 1.249 ENSMUST00000111859.1
ENSMUST00000148865.1
Rgl1

ral guanine nucleotide dissociation stimulator,-like 1

chr5_+_135168382 1.239 ENSMUST00000111187.3
ENSMUST00000111188.1
Bcl7b

B cell CLL/lymphoma 7B

chr7_-_4752972 1.169 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr7_+_28693032 1.133 ENSMUST00000151227.1
ENSMUST00000108281.1
Fbxo27

F-box protein 27

chr15_+_55112317 1.126 ENSMUST00000096433.3
Deptor
DEP domain containing MTOR-interacting protein
chr2_+_140395446 1.110 ENSMUST00000110061.1
Macrod2
MACRO domain containing 2
chr1_-_152766323 1.108 ENSMUST00000111857.1
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr14_-_31019055 1.076 ENSMUST00000037739.6
Gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr1_+_87264345 1.054 ENSMUST00000118687.1
ENSMUST00000027472.6
Efhd1

EF hand domain containing 1

chr11_-_115001880 1.044 ENSMUST00000092464.3
AF251705
cDNA sequence AF251705
chr11_-_77489666 1.006 ENSMUST00000037593.7
ENSMUST00000092892.3
Ankrd13b

ankyrin repeat domain 13b

chr5_+_135168283 1.004 ENSMUST00000031692.5
Bcl7b
B cell CLL/lymphoma 7B
chr14_-_54926784 0.952 ENSMUST00000022813.6
Efs
embryonal Fyn-associated substrate
chr4_+_101419696 0.906 ENSMUST00000131397.1
ENSMUST00000133055.1
Ak4

adenylate kinase 4

chr17_-_46031813 0.904 ENSMUST00000024747.7
Vegfa
vascular endothelial growth factor A
chr3_-_88503187 0.896 ENSMUST00000120377.1
Lmna
lamin A
chr7_-_51862216 0.858 ENSMUST00000169357.1
Fancf
Fanconi anemia, complementation group F
chr3_-_88503331 0.836 ENSMUST00000029699.6
Lmna
lamin A
chr1_+_152766540 0.826 ENSMUST00000077755.5
ENSMUST00000097536.4
Arpc5

actin related protein 2/3 complex, subunit 5

chrX_+_140664908 0.790 ENSMUST00000112990.1
ENSMUST00000112988.1
Mid2

midline 2

chr4_+_129984833 0.770 ENSMUST00000120204.1
Bai2
brain-specific angiogenesis inhibitor 2
chr14_+_60634719 0.760 ENSMUST00000022566.7
ENSMUST00000159729.1
Spata13

spermatogenesis associated 13

chr2_-_93334467 0.760 ENSMUST00000111265.2
Tspan18
tetraspanin 18
chr4_+_46450892 0.760 ENSMUST00000102926.4
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr4_+_129985098 0.753 ENSMUST00000106017.1
ENSMUST00000121049.1
Bai2

brain-specific angiogenesis inhibitor 2

chr5_-_44226601 0.733 ENSMUST00000055128.7
Tapt1
transmembrane anterior posterior transformation 1
chr4_-_126753372 0.730 ENSMUST00000030637.7
ENSMUST00000106116.1
Ncdn

neurochondrin

chr11_+_102189620 0.687 ENSMUST00000070334.3
ENSMUST00000078975.7
G6pc3

glucose 6 phosphatase, catalytic, 3

chr4_+_134468320 0.675 ENSMUST00000030636.4
ENSMUST00000127279.1
ENSMUST00000105867.1
Stmn1


stathmin 1


chr10_+_17723220 0.672 ENSMUST00000038107.7
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr8_+_4248188 0.667 ENSMUST00000110993.1
Gm14378
predicted gene 14378
chr17_-_27728889 0.651 ENSMUST00000167489.1
ENSMUST00000138970.1
ENSMUST00000114870.1
ENSMUST00000025054.2
Spdef



SAM pointed domain containing ets transcription factor



chr12_+_117843489 0.649 ENSMUST00000021592.9
Cdca7l
cell division cycle associated 7 like
chr11_+_113619318 0.629 ENSMUST00000146390.2
ENSMUST00000106630.1
Sstr2

somatostatin receptor 2

chr3_-_95882193 0.619 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
Gm129


predicted gene 129


chr11_-_100939357 0.612 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr6_+_17306335 0.587 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
Cav1



caveolin 1, caveolae protein



chr5_-_138996087 0.560 ENSMUST00000110897.1
Pdgfa
platelet derived growth factor, alpha
chr9_+_107587711 0.560 ENSMUST00000010192.5
Ifrd2
interferon-related developmental regulator 2
chr14_-_55784007 0.550 ENSMUST00000002398.7
Adcy4
adenylate cyclase 4
chr4_+_129513581 0.530 ENSMUST00000062356.6
Marcksl1
MARCKS-like 1
chr11_+_120348678 0.516 ENSMUST00000143813.1
0610009L18Rik
RIKEN cDNA 0610009L18 gene
chr14_-_55784027 0.508 ENSMUST00000170223.1
Adcy4
adenylate cyclase 4
chr7_-_25658726 0.505 ENSMUST00000071329.6
Bckdha
branched chain ketoacid dehydrogenase E1, alpha polypeptide
chrX_-_8074720 0.503 ENSMUST00000115636.3
ENSMUST00000115638.3
Suv39h1

suppressor of variegation 3-9 homolog 1 (Drosophila)

chr6_-_5496296 0.499 ENSMUST00000019721.4
Pdk4
pyruvate dehydrogenase kinase, isoenzyme 4
chr5_+_146948640 0.491 ENSMUST00000146511.1
ENSMUST00000132102.1
Gtf3a

general transcription factor III A

chr2_-_164190601 0.489 ENSMUST00000051272.7
Wfdc12
WAP four-disulfide core domain 12
chr7_-_62420139 0.474 ENSMUST00000094340.3
Mkrn3
makorin, ring finger protein, 3
chr11_+_115420138 0.459 ENSMUST00000106533.1
ENSMUST00000123345.1
Kctd2

potassium channel tetramerisation domain containing 2

chr3_-_95315086 0.457 ENSMUST00000098867.3
Gm10691
predicted gene 10691
chr3_-_89418287 0.454 ENSMUST00000029679.3
Cks1b
CDC28 protein kinase 1b
chr11_-_106388066 0.436 ENSMUST00000106813.2
ENSMUST00000141146.1
Icam2

intercellular adhesion molecule 2

chr4_+_118428078 0.433 ENSMUST00000006557.6
ENSMUST00000167636.1
ENSMUST00000102673.4
Elovl1


elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1


chr7_+_27486910 0.432 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr12_+_65036319 0.431 ENSMUST00000120580.1
Prpf39
PRP39 pre-mRNA processing factor 39 homolog (yeast)
chr3_-_95882031 0.426 ENSMUST00000161994.1
Gm129
predicted gene 129
chr9_-_56418023 0.422 ENSMUST00000061552.8
C230081A13Rik
RIKEN cDNA C230081A13 gene
chrX_+_71555918 0.413 ENSMUST00000072699.6
ENSMUST00000114582.2
ENSMUST00000015361.4
ENSMUST00000088874.3
Hmgb3



high mobility group box 3



chr7_+_79500018 0.410 ENSMUST00000182495.1
ENSMUST00000183043.1
AI854517

expressed sequence AI854517

chr9_-_36726374 0.408 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1


checkpoint kinase 1


chr6_+_17306415 0.404 ENSMUST00000150901.1
Cav1
caveolin 1, caveolae protein
chr7_+_101321703 0.396 ENSMUST00000174291.1
ENSMUST00000167888.2
ENSMUST00000172662.1
ENSMUST00000173270.1
ENSMUST00000174083.1
Stard10




START domain containing 10




chr2_-_160912292 0.395 ENSMUST00000109454.1
ENSMUST00000057169.4
Emilin3

elastin microfibril interfacer 3

chr4_-_129239165 0.392 ENSMUST00000097873.3
C77080
expressed sequence C77080
chr1_+_92906959 0.386 ENSMUST00000060913.6
Dusp28
dual specificity phosphatase 28
chr7_-_90457167 0.366 ENSMUST00000032844.5
Tmem126a
transmembrane protein 126A
chr10_+_80141457 0.357 ENSMUST00000105367.1
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr4_+_148804420 0.355 ENSMUST00000094464.3
ENSMUST00000122222.1
Casz1

castor zinc finger 1

chr9_-_103480328 0.345 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr11_+_115420059 0.338 ENSMUST00000103035.3
Kctd2
potassium channel tetramerisation domain containing 2
chr4_+_156235999 0.320 ENSMUST00000179543.1
ENSMUST00000179886.1
Noc2l

nucleolar complex associated 2 homolog (S. cerevisiae)

chr7_-_118491912 0.315 ENSMUST00000178344.1
Itpripl2
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr8_-_47289394 0.295 ENSMUST00000079195.5
Stox2
storkhead box 2
chr10_+_80142295 0.294 ENSMUST00000003156.8
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr9_-_54661666 0.294 ENSMUST00000128624.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr19_+_6418731 0.291 ENSMUST00000113462.1
ENSMUST00000077182.6
ENSMUST00000113461.1
Nrxn2


neurexin II


chr3_-_95882232 0.289 ENSMUST00000161866.1
Gm129
predicted gene 129
chrX_+_69360294 0.286 ENSMUST00000033532.6
Aff2
AF4/FMR2 family, member 2
chr4_-_24851079 0.285 ENSMUST00000084781.5
ENSMUST00000108218.3
Klhl32

kelch-like 32

chr7_+_141447645 0.284 ENSMUST00000106004.1
ENSMUST00000106003.1
Rplp2

ribosomal protein, large P2

chr4_+_148591482 0.279 ENSMUST00000006611.8
Srm
spermidine synthase
chr5_-_139484420 0.279 ENSMUST00000150992.1
Zfand2a
zinc finger, AN1-type domain 2A
chr8_+_85060055 0.276 ENSMUST00000095220.3
Fbxw9
F-box and WD-40 domain protein 9
chr1_-_22805994 0.273 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chr4_+_138304723 0.268 ENSMUST00000030538.4
Ddost
dolichyl-di-phosphooligosaccharide-protein glycotransferase
chr14_-_31830402 0.258 ENSMUST00000014640.7
Ankrd28
ankyrin repeat domain 28
chr3_-_88177671 0.250 ENSMUST00000181837.1
1700113A16Rik
RIKEN cDNA 1700113A16 gene
chr10_+_80142358 0.250 ENSMUST00000105366.1
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr1_+_164249052 0.248 ENSMUST00000159230.1
Slc19a2
solute carrier family 19 (thiamine transporter), member 2
chr10_-_117376955 0.245 ENSMUST00000069168.6
ENSMUST00000176686.1
Cpsf6

cleavage and polyadenylation specific factor 6

chr12_-_75735729 0.237 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr13_-_49652714 0.234 ENSMUST00000021818.7
Cenpp
centromere protein P
chr3_+_89418443 0.228 ENSMUST00000039110.5
ENSMUST00000125036.1
ENSMUST00000154791.1
ENSMUST00000128238.1
ENSMUST00000107417.2
Shc1




src homology 2 domain-containing transforming protein C1




chr4_+_155993143 0.227 ENSMUST00000097734.4
Sdf4
stromal cell derived factor 4
chr7_+_80261202 0.222 ENSMUST00000117989.1
Ngrn
neugrin, neurite outgrowth associated
chr1_+_59684949 0.221 ENSMUST00000027174.3
Nop58
NOP58 ribonucleoprotein
chr8_+_71568866 0.218 ENSMUST00000034267.4
Slc27a1
solute carrier family 27 (fatty acid transporter), member 1
chr15_+_100615620 0.218 ENSMUST00000000356.8
Dazap2
DAZ associated protein 2
chr10_+_80494835 0.213 ENSMUST00000051773.8
Onecut3
one cut domain, family member 3
chr11_-_115419917 0.205 ENSMUST00000106537.1
ENSMUST00000043931.2
ENSMUST00000073791.3
Atp5h


ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d


chr7_+_79500081 0.204 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr11_+_9048575 0.202 ENSMUST00000043285.4
Gm11992
predicted gene 11992
chr1_+_164249023 0.200 ENSMUST00000044021.5
Slc19a2
solute carrier family 19 (thiamine transporter), member 2
chr4_-_117133953 0.193 ENSMUST00000076859.5
Plk3
polo-like kinase 3
chr1_-_16519201 0.186 ENSMUST00000159558.1
ENSMUST00000054668.6
ENSMUST00000162627.1
ENSMUST00000162007.1
ENSMUST00000128957.2
ENSMUST00000115359.3
ENSMUST00000151888.1
Stau2






staufen (RNA binding protein) homolog 2 (Drosophila)






chr10_-_11080956 0.183 ENSMUST00000105560.1
Grm1
glutamate receptor, metabotropic 1
chr6_+_125009665 0.181 ENSMUST00000046064.10
ENSMUST00000152752.1
ENSMUST00000088308.3
ENSMUST00000112425.1
ENSMUST00000084275.5
Zfp384




zinc finger protein 384




chr16_+_92058270 0.179 ENSMUST00000047429.8
ENSMUST00000113975.2
Mrps6
Slc5a3
mitochondrial ribosomal protein S6
solute carrier family 5 (inositol transporters), member 3
chr11_+_62248977 0.174 ENSMUST00000018644.2
Adora2b
adenosine A2b receptor
chr1_+_36511867 0.174 ENSMUST00000001166.7
ENSMUST00000097776.3
Cnnm3

cyclin M3

chr11_+_103966716 0.173 ENSMUST00000057921.3
ENSMUST00000063347.5
Arf2

ADP-ribosylation factor 2

chr14_-_70351354 0.169 ENSMUST00000143153.1
ENSMUST00000127000.1
ENSMUST00000068044.7
ENSMUST00000022688.3
Slc39a14



solute carrier family 39 (zinc transporter), member 14



chr3_+_87906321 0.150 ENSMUST00000005017.8
Hdgf
hepatoma-derived growth factor
chr9_+_22156838 0.150 ENSMUST00000123680.1
Pigyl
phosphatidylinositol glycan anchor biosynthesis, class Y-like
chr1_+_172482199 0.141 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
Igsf9


immunoglobulin superfamily, member 9


chr3_+_81932601 0.139 ENSMUST00000029649.2
Ctso
cathepsin O
chr14_+_45219993 0.126 ENSMUST00000146150.1
Gpr137c
G protein-coupled receptor 137C
chr1_-_82586781 0.126 ENSMUST00000087050.5
Col4a4
collagen, type IV, alpha 4
chr9_+_60794468 0.123 ENSMUST00000050183.6
Uaca
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr4_-_107683576 0.122 ENSMUST00000131776.1
Dmrtb1
DMRT-like family B with proline-rich C-terminal, 1
chr7_-_27166413 0.116 ENSMUST00000108382.1
Egln2
EGL nine homolog 2 (C. elegans)
chr5_-_36398090 0.108 ENSMUST00000037370.7
ENSMUST00000070720.6
Sorcs2

sortilin-related VPS10 domain containing receptor 2

chr9_+_22156903 0.103 ENSMUST00000148088.1
Pigyl
phosphatidylinositol glycan anchor biosynthesis, class Y-like
chr17_-_31512253 0.099 ENSMUST00000166626.1
Wdr4
WD repeat domain 4
chr8_+_119394866 0.095 ENSMUST00000098367.4
Mlycd
malonyl-CoA decarboxylase
chr14_-_79481268 0.095 ENSMUST00000022601.5
Wbp4
WW domain binding protein 4
chr15_-_76009440 0.091 ENSMUST00000170153.1
Fam83h
family with sequence similarity 83, member H
chr12_-_103242143 0.091 ENSMUST00000074416.3
Prima1
proline rich membrane anchor 1
chr1_-_16519284 0.090 ENSMUST00000162751.1
ENSMUST00000027052.6
ENSMUST00000149320.2
Stau2


staufen (RNA binding protein) homolog 2 (Drosophila)


chr10_+_79854658 0.089 ENSMUST00000171599.1
ENSMUST00000095457.4
Ptbp1

polypyrimidine tract binding protein 1

chr11_+_88999376 0.081 ENSMUST00000100627.2
ENSMUST00000107896.3
ENSMUST00000000284.6
Trim25


tripartite motif-containing 25


chr4_-_126968124 0.081 ENSMUST00000106108.2
Zmym4
zinc finger, MYM-type 4
chr10_+_79854618 0.078 ENSMUST00000165704.1
Ptbp1
polypyrimidine tract binding protein 1
chr6_+_125192154 0.076 ENSMUST00000032485.5
Mrpl51
mitochondrial ribosomal protein L51
chr18_+_76242135 0.072 ENSMUST00000172198.1
Smad2
SMAD family member 2
chr10_+_7667503 0.072 ENSMUST00000040135.8
Nup43
nucleoporin 43
chr17_+_47611570 0.068 ENSMUST00000024778.2
Med20
mediator complex subunit 20
chr8_-_94012558 0.065 ENSMUST00000053766.6
Amfr
autocrine motility factor receptor
chr4_-_11966368 0.063 ENSMUST00000056050.4
ENSMUST00000108299.1
ENSMUST00000108297.2
Pdp1


pyruvate dehyrogenase phosphatase catalytic subunit 1


chr2_+_24949747 0.061 ENSMUST00000028350.3
Zmynd19
zinc finger, MYND domain containing 19
chr4_+_33924632 0.061 ENSMUST00000057188.6
Cnr1
cannabinoid receptor 1 (brain)
chr9_-_114933929 0.060 ENSMUST00000146623.1
Gpd1l
glycerol-3-phosphate dehydrogenase 1-like
chr14_-_67933512 0.058 ENSMUST00000039135.4
Dock5
dedicator of cytokinesis 5
chr2_-_168742100 0.057 ENSMUST00000109177.1
Atp9a
ATPase, class II, type 9A
chr17_-_27909206 0.056 ENSMUST00000114848.1
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr3_+_105452326 0.054 ENSMUST00000098761.3
Kcnd3
potassium voltage-gated channel, Shal-related family, member 3
chr16_-_22657165 0.047 ENSMUST00000089925.3
Dgkg
diacylglycerol kinase, gamma
chr15_-_39112642 0.047 ENSMUST00000022908.8
Slc25a32
solute carrier family 25, member 32
chr11_-_97700327 0.039 ENSMUST00000018681.7
Pcgf2
polycomb group ring finger 2
chr2_+_153345809 0.039 ENSMUST00000109790.1
Asxl1
additional sex combs like 1
chr16_+_94085226 0.033 ENSMUST00000072182.7
Sim2
single-minded homolog 2 (Drosophila)
chr6_-_88874597 0.032 ENSMUST00000061262.4
ENSMUST00000140455.1
ENSMUST00000145780.1
Podxl2


podocalyxin-like 2


chr9_+_103112072 0.028 ENSMUST00000035155.6
Rab6b
RAB6B, member RAS oncogene family
chr2_-_168741898 0.024 ENSMUST00000109176.1
ENSMUST00000178504.1
Atp9a

ATPase, class II, type 9A

chr10_+_127739516 0.006 ENSMUST00000054287.7
Zbtb39
zinc finger and BTB domain containing 39
chr10_-_75517324 0.005 ENSMUST00000039796.7
Gucd1
guanylyl cyclase domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0060166 olfactory pit development(GO:0060166)
0.8 2.4 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.6 1.7 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.5 2.4 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.4 1.7 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.3 0.9 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.3 2.6 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.3 1.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.3 2.9 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.2 2.0 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.2 0.2 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.2 0.7 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 0.6 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.2 1.0 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
0.2 0.6 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.2 0.7 GO:0061428 embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.2 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 0.3 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.1 1.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.0 GO:0010454 negative regulation of cell fate commitment(GO:0010454)
0.1 1.5 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.3 GO:0015888 thiamine transport(GO:0015888)
0.1 0.4 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.2 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.1 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.6 GO:0030432 peristalsis(GO:0030432)
0.1 0.3 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.3 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.4 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 1.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.4 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1 0.9 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 1.1 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.1 0.2 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.1 2.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.5 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.2 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.9 GO:0046033 AMP metabolic process(GO:0046033)
0.0 2.4 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.7 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.4 GO:0021554 optic nerve development(GO:0021554)
0.0 0.1 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.0 0.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:1900145 regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) positive regulation of mesoderm development(GO:2000382)
0.0 0.8 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.2 GO:0015791 polyol transport(GO:0015791)
0.0 0.2 GO:0090166 Golgi disassembly(GO:0090166)
0.0 1.9 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:0031622 positive regulation of fever generation(GO:0031622)
0.0 0.0 GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035358)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.3 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.7 GO:0045453 bone resorption(GO:0045453)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.9 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.1 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.8 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.6 2.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.5 1.5 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.2 1.7 GO:0005638 lamin filament(GO:0005638)
0.1 1.9 GO:0005922 connexon complex(GO:0005922)
0.1 0.5 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.3 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.2 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 1.0 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.4 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 1.4 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.2 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.8 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.6 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.5 2.7 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.4 2.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.4 2.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 0.9 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3 0.9 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 1.7 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 0.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 1.0 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.2 1.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 2.0 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.1 1.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.3 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 1.1 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.1 0.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.7 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 0.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.3 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 0.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 1.1 GO:0042287 MHC protein binding(GO:0042287)
0.1 1.2 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639)
0.0 0.5 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.4 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0048407 platelet-derived growth factor receptor binding(GO:0005161) platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 2.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 3.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.0 0.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)