Motif ID: Hey2
Z-value: 1.038
Transcription factors associated with Hey2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hey2 | ENSMUSG00000019789.8 | Hey2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hey2 | mm10_v2_chr10_-_30842765_30842801 | 0.14 | 6.3e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.7 | GO:0060166 | olfactory pit development(GO:0060166) |
0.8 | 2.4 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
0.6 | 1.7 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
0.5 | 2.4 | GO:2000680 | regulation of rubidium ion transport(GO:2000680) |
0.4 | 1.7 | GO:1904177 | regulation of adipose tissue development(GO:1904177) |
0.3 | 0.9 | GO:1902336 | neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) |
0.3 | 2.6 | GO:0021894 | cerebral cortex GABAergic interneuron development(GO:0021894) |
0.3 | 1.1 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
0.3 | 2.9 | GO:0034312 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
0.2 | 2.0 | GO:0000050 | urea cycle(GO:0000050) urea metabolic process(GO:0019627) |
0.2 | 0.2 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
0.2 | 0.7 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
0.2 | 0.6 | GO:1904685 | positive regulation of metalloendopeptidase activity(GO:1904685) |
0.2 | 1.0 | GO:1900085 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) |
0.2 | 0.6 | GO:0010512 | negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) |
0.2 | 0.7 | GO:0061428 | embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
0.1 | 0.5 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
0.1 | 0.8 | GO:0035372 | protein localization to microtubule(GO:0035372) |
0.1 | 0.2 | GO:0071072 | negative regulation of phospholipid biosynthetic process(GO:0071072) |
0.1 | 0.3 | GO:0032066 | nucleolus to nucleoplasm transport(GO:0032066) |
0.1 | 1.9 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
0.1 | 0.8 | GO:0051639 | actin filament network formation(GO:0051639) |
0.1 | 1.0 | GO:0010454 | negative regulation of cell fate commitment(GO:0010454) |
0.1 | 1.5 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
0.1 | 0.3 | GO:0015888 | thiamine transport(GO:0015888) |
0.1 | 0.4 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
0.1 | 0.2 | GO:0070625 | zymogen granule exocytosis(GO:0070625) |
0.1 | 0.2 | GO:0048254 | snoRNA localization(GO:0048254) |
0.1 | 0.6 | GO:0030432 | peristalsis(GO:0030432) |
0.1 | 0.3 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
0.1 | 0.3 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.1 | 0.4 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
0.1 | 1.1 | GO:0045792 | negative regulation of cell size(GO:0045792) |
0.1 | 0.4 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
0.1 | 0.9 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
0.1 | 1.1 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
0.1 | 0.2 | GO:0002678 | positive regulation of chronic inflammatory response(GO:0002678) |
0.1 | 2.1 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
0.1 | 0.4 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.1 | 0.5 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
0.0 | 0.2 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
0.0 | 0.9 | GO:0046033 | AMP metabolic process(GO:0046033) |
0.0 | 2.4 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
0.0 | 0.7 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.0 | 0.4 | GO:0021554 | optic nerve development(GO:0021554) |
0.0 | 0.1 | GO:0015938 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) |
0.0 | 0.5 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
0.0 | 0.3 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
0.0 | 0.3 | GO:0070307 | lens fiber cell development(GO:0070307) |
0.0 | 0.1 | GO:1900145 | regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) positive regulation of mesoderm development(GO:2000382) |
0.0 | 0.8 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
0.0 | 0.2 | GO:0015791 | polyol transport(GO:0015791) |
0.0 | 0.2 | GO:0090166 | Golgi disassembly(GO:0090166) |
0.0 | 1.9 | GO:0007601 | visual perception(GO:0007601) |
0.0 | 0.1 | GO:0031622 | positive regulation of fever generation(GO:0031622) |
0.0 | 0.0 | GO:0035358 | regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035358) |
0.0 | 0.2 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
0.0 | 0.3 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
0.0 | 0.1 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
0.0 | 0.2 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.0 | 0.2 | GO:0045907 | positive regulation of vasoconstriction(GO:0045907) |
0.0 | 0.1 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
0.0 | 0.1 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
0.0 | 0.2 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
0.0 | 0.4 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.0 | 0.7 | GO:0045453 | bone resorption(GO:0045453) |
0.0 | 0.4 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.9 | GO:0001541 | ovarian follicle development(GO:0001541) |
0.0 | 0.1 | GO:0042135 | neurotransmitter catabolic process(GO:0042135) |
0.0 | 0.8 | GO:0046847 | filopodium assembly(GO:0046847) |
0.0 | 0.1 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.0 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
0.6 | 2.4 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
0.5 | 1.5 | GO:0034684 | integrin alphav-beta5 complex(GO:0034684) |
0.2 | 1.7 | GO:0005638 | lamin filament(GO:0005638) |
0.1 | 1.9 | GO:0005922 | connexon complex(GO:0005922) |
0.1 | 0.5 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
0.1 | 0.3 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
0.1 | 0.5 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.1 | 1.2 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.1 | 0.8 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.1 | 1.0 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.1 | 0.9 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
0.1 | 1.9 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.4 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.0 | 0.4 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.0 | 0.4 | GO:0000243 | commitment complex(GO:0000243) |
0.0 | 0.2 | GO:0005796 | Golgi lumen(GO:0005796) |
0.0 | 0.1 | GO:0043293 | apoptosome(GO:0043293) |
0.0 | 1.4 | GO:0031941 | filamentous actin(GO:0031941) |
0.0 | 0.2 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.0 | 2.0 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.2 | GO:0038037 | G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648) |
0.0 | 0.2 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.0 | 0.1 | GO:0032444 | activin responsive factor complex(GO:0032444) |
0.0 | 0.2 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 1.1 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 0.3 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.0 | 0.3 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 2.8 | GO:0008021 | synaptic vesicle(GO:0008021) |
0.0 | 0.6 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 0.9 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.8 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 2.3 | GO:0043209 | myelin sheath(GO:0043209) |
0.0 | 0.6 | GO:0005902 | microvillus(GO:0005902) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.9 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
0.5 | 2.7 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
0.4 | 2.4 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.4 | 2.4 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.3 | 0.9 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
0.3 | 0.9 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.3 | 1.7 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
0.2 | 0.6 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.2 | 1.0 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
0.2 | 1.9 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
0.1 | 0.4 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
0.1 | 0.5 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
0.1 | 2.0 | GO:0001013 | RNA polymerase I regulatory region DNA binding(GO:0001013) |
0.1 | 1.1 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.1 | 0.3 | GO:0015234 | thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) |
0.1 | 1.1 | GO:0070636 | single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694) |
0.1 | 0.7 | GO:0050693 | LBD domain binding(GO:0050693) |
0.1 | 0.9 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
0.1 | 0.7 | GO:0050308 | sugar-phosphatase activity(GO:0050308) |
0.1 | 0.6 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.1 | 0.3 | GO:0031493 | nucleosomal histone binding(GO:0031493) |
0.1 | 0.5 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
0.1 | 1.7 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 0.2 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
0.1 | 1.1 | GO:0042287 | MHC protein binding(GO:0042287) |
0.1 | 1.2 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.2 | GO:0001639 | PLC activating G-protein coupled glutamate receptor activity(GO:0001639) |
0.0 | 0.5 | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624) |
0.0 | 0.4 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.0 | 0.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 0.6 | GO:0048407 | platelet-derived growth factor receptor binding(GO:0005161) platelet-derived growth factor binding(GO:0048407) |
0.0 | 0.3 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
0.0 | 0.2 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
0.0 | 0.1 | GO:0008176 | tRNA (guanine-N7-)-methyltransferase activity(GO:0008176) |
0.0 | 0.8 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 0.2 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.0 | 2.6 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 0.1 | GO:1990254 | keratin filament binding(GO:1990254) |
0.0 | 0.3 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 0.2 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
0.0 | 0.2 | GO:0015166 | polyol transmembrane transporter activity(GO:0015166) |
0.0 | 0.3 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.0 | 2.0 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.2 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
0.0 | 0.1 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
0.0 | 3.6 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 0.1 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.0 | 0.1 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
0.0 | 0.1 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
0.0 | 0.4 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.0 | 0.1 | GO:0043495 | protein anchor(GO:0043495) |
0.0 | 0.2 | GO:0017161 | phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003) |
0.0 | 0.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.1 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |