Motif ID: Hic1

Z-value: 1.664


Transcription factors associated with Hic1:

Gene SymbolEntrez IDGene Name
Hic1 ENSMUSG00000043099.4 Hic1



Activity profile for motif Hic1.

activity profile for motif Hic1


Sorted Z-values histogram for motif Hic1

Sorted Z-values for motif Hic1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hic1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_83631892 2.759 ENSMUST00000051482.1
 Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr11_-_66525964 2.330 ENSMUST00000066679.6
 Shisa6
shisa homolog 6 (Xenopus laevis)
chr17_-_32788284 2.190 ENSMUST00000159086.2
 Zfp871
zinc finger protein 871
chr11_+_7063423 2.171 ENSMUST00000020706.4
 Adcy1
adenylate cyclase 1
chr6_+_17463826 2.100 ENSMUST00000140070.1
 Met
met proto-oncogene
chr2_-_57124003 1.995 ENSMUST00000112629.1
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr13_+_109903089 1.927 ENSMUST00000120664.1
 Pde4d
phosphodiesterase 4D, cAMP specific
chr12_+_95695350 1.746 ENSMUST00000110117.1
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr6_+_7844806 1.739 ENSMUST00000040159.4
 C1galt1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr6_+_17463927 1.673 ENSMUST00000115442.1
 Met
met proto-oncogene
chr7_-_118243564 1.655 ENSMUST00000179047.1
ENSMUST00000032891.8
 Smg1

SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)

chr4_-_149307506 1.590 ENSMUST00000055647.8
ENSMUST00000030806.5
ENSMUST00000060537.6
 Kif1b


kinesin family member 1B


chr6_-_32588192 1.571 ENSMUST00000115096.2
 Plxna4
plexin A4
chr6_+_17463749 1.562 ENSMUST00000115443.1
 Met
met proto-oncogene
chr6_-_38876163 1.538 ENSMUST00000161779.1
 Hipk2
homeodomain interacting protein kinase 2
chr4_-_123664725 1.512 ENSMUST00000147030.1
 Macf1
microtubule-actin crosslinking factor 1
chr19_+_57611020 1.464 ENSMUST00000077282.5
 Atrnl1
attractin like 1
chr2_-_157079212 1.462 ENSMUST00000069098.6
 Soga1
suppressor of glucose, autophagy associated 1
chr6_-_38875965 1.454 ENSMUST00000160360.1
 Hipk2
homeodomain interacting protein kinase 2
chr9_+_26733845 1.447 ENSMUST00000115269.2
 B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 408 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 5.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.5 4.0 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.2 3.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 3.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 3.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 3.1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.2 2.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.5 2.7 GO:0001778 plasma membrane repair(GO:0001778)
0.2 2.3 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.2 2.2 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.5 2.0 GO:0051866 general adaptation syndrome(GO:0051866)
0.4 2.0 GO:0016266 O-glycan processing(GO:0016266)
0.1 2.0 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1 2.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.5 1.9 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 1.8 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.2 1.7 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 1.7 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 1.7 GO:0050879 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.5 1.6 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 155 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.5 GO:0060076 excitatory synapse(GO:0060076)
0.1 7.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 4.9 GO:0016605 PML body(GO:0016605)
0.1 4.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 3.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 3.0 GO:0048786 presynaptic active zone(GO:0048786)
0.0 3.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.5 GO:0005776 autophagosome(GO:0005776)
0.0 2.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.4 2.2 GO:0097513 myosin II filament(GO:0097513)
0.0 1.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 1.7 GO:0008278 cohesin complex(GO:0008278)
0.2 1.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 1.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.7 GO:0001527 microfibril(GO:0001527)
0.3 1.6 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 1.6 GO:0005871 kinesin complex(GO:0005871)
0.1 1.5 GO:0000145 exocyst(GO:0000145)
0.1 1.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 252 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.2 GO:0003779 actin binding(GO:0003779)
0.2 5.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
1.3 5.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.5 3.9 GO:0046790 virion binding(GO:0046790)
0.1 3.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 3.6 GO:0005096 GTPase activator activity(GO:0005096)
0.5 2.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 2.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 2.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 2.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.4 2.3 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 2.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 2.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 2.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 2.1 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 2.0 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.4 1.9 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)