Motif ID: Hif1a

Z-value: 1.022


Transcription factors associated with Hif1a:

Gene SymbolEntrez IDGene Name
Hif1a ENSMUSG00000021109.7 Hif1a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hif1amm10_v2_chr12_+_73901370_73901391-0.431.2e-01Click!


Activity profile for motif Hif1a.

activity profile for motif Hif1a


Sorted Z-values histogram for motif Hif1a

Sorted Z-values for motif Hif1a



Network of associatons between targets according to the STRING database.



First level regulatory network of Hif1a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_45999860 2.025 ENSMUST00000053558.9
Ankrd37
ankyrin repeat domain 37
chr7_+_46845832 1.702 ENSMUST00000048209.9
ENSMUST00000092621.4
Ldha

lactate dehydrogenase A

chr19_-_44069690 1.293 ENSMUST00000169092.1
Erlin1
ER lipid raft associated 1
chr13_-_52981027 1.291 ENSMUST00000071065.7
Nfil3
nuclear factor, interleukin 3, regulated
chr13_-_29984219 1.156 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr17_-_27133902 0.993 ENSMUST00000119227.1
ENSMUST00000025045.8
Uqcc2

ubiquinol-cytochrome c reductase complex assembly factor 2

chr17_-_27133620 0.966 ENSMUST00000118613.1
Uqcc2
ubiquinol-cytochrome c reductase complex assembly factor 2
chr15_+_44787746 0.841 ENSMUST00000181839.1
2310069G16Rik
RIKEN cDNA 2310069G16 gene
chr1_+_74771886 0.825 ENSMUST00000006716.6
Wnt6
wingless-related MMTV integration site 6
chr14_-_68124836 0.810 ENSMUST00000111089.1
ENSMUST00000022638.5
Nefm

neurofilament, medium polypeptide

chr11_-_120348513 0.729 ENSMUST00000071555.6
Actg1
actin, gamma, cytoplasmic 1
chr11_-_89302545 0.721 ENSMUST00000061728.3
Nog
noggin
chr11_+_121259983 0.703 ENSMUST00000106113.1
Foxk2
forkhead box K2
chr15_-_44788016 0.699 ENSMUST00000090057.4
ENSMUST00000110269.1
Sybu

syntabulin (syntaxin-interacting)

chr8_-_106893581 0.696 ENSMUST00000176437.1
ENSMUST00000177068.1
ENSMUST00000169312.1
ENSMUST00000176515.1
Chtf8



CTF8, chromosome transmission fidelity factor 8



chr6_-_125165707 0.684 ENSMUST00000118875.1
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr11_-_120348475 0.683 ENSMUST00000062147.7
ENSMUST00000128055.1
Actg1

actin, gamma, cytoplasmic 1

chrX_-_93832106 0.680 ENSMUST00000045748.6
Pdk3
pyruvate dehydrogenase kinase, isoenzyme 3
chr8_-_106893515 0.677 ENSMUST00000176090.1
Chtf8
CTF8, chromosome transmission fidelity factor 8
chr6_-_72958465 0.663 ENSMUST00000114050.1
Tmsb10
thymosin, beta 10
chr2_-_163419508 0.659 ENSMUST00000046908.3
Oser1
oxidative stress responsive serine rich 1
chr9_+_107569112 0.649 ENSMUST00000010191.7
Hyal2
hyaluronoglucosaminidase 2
chr2_+_168081004 0.645 ENSMUST00000052125.6
Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr2_-_14056029 0.630 ENSMUST00000074854.7
Ptpla
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a
chr10_-_59951753 0.630 ENSMUST00000020308.3
Ddit4
DNA-damage-inducible transcript 4
chr5_+_129020069 0.630 ENSMUST00000031383.7
ENSMUST00000111343.1
Ran

RAN, member RAS oncogene family

chr16_-_23988852 0.629 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr2_-_130582554 0.626 ENSMUST00000046001.6
Avp
arginine vasopressin
chrX_+_143518671 0.619 ENSMUST00000134402.1
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr4_+_150237211 0.611 ENSMUST00000133839.1
Eno1
enolase 1, alpha non-neuron
chr4_+_150236685 0.599 ENSMUST00000150175.1
Eno1
enolase 1, alpha non-neuron
chr10_-_78009737 0.597 ENSMUST00000020522.8
Pfkl
phosphofructokinase, liver, B-type
chr11_-_120348091 0.595 ENSMUST00000106215.4
Actg1
actin, gamma, cytoplasmic 1
chr5_-_122779278 0.594 ENSMUST00000111668.3
Camkk2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr11_-_96065350 0.574 ENSMUST00000100528.4
Ube2z
ubiquitin-conjugating enzyme E2Z (putative)
chr4_+_116877376 0.572 ENSMUST00000044823.3
Zswim5
zinc finger SWIM-type containing 5
chr2_-_14055963 0.572 ENSMUST00000091429.5
ENSMUST00000114753.1
Ptpla

protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a

chr4_+_150236816 0.565 ENSMUST00000080926.6
Eno1
enolase 1, alpha non-neuron
chr14_-_18894255 0.564 ENSMUST00000124353.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr11_-_72411695 0.554 ENSMUST00000108500.1
ENSMUST00000050226.6
Smtnl2

smoothelin-like 2

chr6_+_29272488 0.553 ENSMUST00000115289.1
ENSMUST00000054445.8
Hilpda

hypoxia inducible lipid droplet associated

chr19_-_44069736 0.541 ENSMUST00000172041.1
ENSMUST00000071698.6
ENSMUST00000112028.3
Erlin1


ER lipid raft associated 1


chr8_+_106893616 0.530 ENSMUST00000047629.5
Cirh1a
cirrhosis, autosomal recessive 1A (human)
chr10_+_121739915 0.528 ENSMUST00000065600.7
ENSMUST00000136432.1
BC048403

cDNA sequence BC048403

chr3_-_95882193 0.506 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
Gm129


predicted gene 129


chr6_-_29212240 0.494 ENSMUST00000160878.1
ENSMUST00000078155.5
Impdh1

inosine 5'-phosphate dehydrogenase 1

chr1_+_55088132 0.494 ENSMUST00000075242.6
Hspe1
heat shock protein 1 (chaperonin 10)
chr2_+_68861564 0.493 ENSMUST00000176018.1
Cers6
ceramide synthase 6
chr9_+_106203108 0.488 ENSMUST00000024047.5
Twf2
twinfilin, actin-binding protein, homolog 2 (Drosophila)
chr17_-_26201363 0.487 ENSMUST00000121959.1
Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr14_-_21052452 0.482 ENSMUST00000130291.1
Ap3m1
adaptor-related protein complex 3, mu 1 subunit
chr6_-_125165576 0.473 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
Gapdh


glyceraldehyde-3-phosphate dehydrogenase


chr7_-_45466894 0.458 ENSMUST00000033093.8
Bax
BCL2-associated X protein
chr12_-_79007276 0.454 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr7_-_68749170 0.451 ENSMUST00000118110.1
ENSMUST00000048068.7
Arrdc4

arrestin domain containing 4

chr19_-_44069526 0.449 ENSMUST00000170801.1
Erlin1
ER lipid raft associated 1
chr14_-_18893376 0.444 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr14_-_18893623 0.437 ENSMUST00000177259.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr7_+_129257027 0.434 ENSMUST00000094018.4
Ppapdc1a
phosphatidic acid phosphatase type 2 domain containing 1A
chr17_-_23677432 0.426 ENSMUST00000167059.1
ENSMUST00000024698.8
Tnfrsf12a

tumor necrosis factor receptor superfamily, member 12a

chr3_+_108186332 0.425 ENSMUST00000050909.6
ENSMUST00000106659.2
ENSMUST00000106656.1
ENSMUST00000106661.2
Amigo1



adhesion molecule with Ig like domain 1



chr9_+_21165714 0.423 ENSMUST00000039413.8
Pde4a
phosphodiesterase 4A, cAMP specific
chr4_-_129600586 0.423 ENSMUST00000135055.1
Eif3i
eukaryotic translation initiation factor 3, subunit I
chr1_+_9545397 0.411 ENSMUST00000072079.7
Rrs1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr6_+_125131869 0.405 ENSMUST00000044200.8
Nop2
NOP2 nucleolar protein
chr11_+_78178651 0.403 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
Tlcd1


TLC domain containing 1


chr16_-_20241304 0.399 ENSMUST00000040880.7
Map6d1
MAP6 domain containing 1
chr15_+_101174096 0.392 ENSMUST00000000544.9
Acvr1b
activin A receptor, type 1B
chr5_-_33657889 0.384 ENSMUST00000019439.7
Tmem129
transmembrane protein 129
chr6_+_88724828 0.383 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr14_+_5501674 0.375 ENSMUST00000181562.1
Gm3488
predicted gene, 3488
chr2_+_71873224 0.369 ENSMUST00000006669.5
Pdk1
pyruvate dehydrogenase kinase, isoenzyme 1
chr9_-_35116804 0.363 ENSMUST00000034537.6
St3gal4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr15_+_80287234 0.362 ENSMUST00000160424.1
Cacna1i
calcium channel, voltage-dependent, alpha 1I subunit
chr10_-_85102487 0.360 ENSMUST00000059383.6
Fhl4
four and a half LIM domains 4
chr7_-_105736781 0.358 ENSMUST00000033179.6
Rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr4_-_129600642 0.355 ENSMUST00000102593.4
Eif3i
eukaryotic translation initiation factor 3, subunit I
chr10_-_80387642 0.354 ENSMUST00000062946.6
ENSMUST00000105350.1
Mex3d

mex3 homolog D (C. elegans)

chr7_+_19004047 0.354 ENSMUST00000053713.3
Irf2bp1
interferon regulatory factor 2 binding protein 1
chr5_+_52190650 0.349 ENSMUST00000180601.1
9230114K14Rik
RIKEN cDNA 9230114K14 gene
chr19_+_18713225 0.349 ENSMUST00000055792.7
D030056L22Rik
RIKEN cDNA D030056L22 gene
chr2_-_181459364 0.349 ENSMUST00000155535.1
ENSMUST00000029106.6
ENSMUST00000087409.3
Zbtb46


zinc finger and BTB domain containing 46


chr6_+_88724667 0.345 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr8_+_83997613 0.336 ENSMUST00000095228.3
Samd1
sterile alpha motif domain containing 1
chr14_+_4182576 0.335 ENSMUST00000164512.1
Gm2974
predicted gene 2974
chr11_-_102819663 0.332 ENSMUST00000092567.4
Gjc1
gap junction protein, gamma 1
chr17_+_46681038 0.327 ENSMUST00000002845.6
Mea1
male enhanced antigen 1
chr7_+_30169861 0.326 ENSMUST00000085668.4
Gm5113
predicted gene 5113
chr1_+_42952872 0.326 ENSMUST00000179766.1
Gpr45
G protein-coupled receptor 45
chr4_-_21685782 0.324 ENSMUST00000076206.4
Prdm13
PR domain containing 13
chr5_-_135251209 0.321 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr6_+_88724489 0.317 ENSMUST00000113581.1
Mgll
monoglyceride lipase
chr14_-_18893749 0.312 ENSMUST00000150727.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr7_+_28693032 0.310 ENSMUST00000151227.1
ENSMUST00000108281.1
Fbxo27

F-box protein 27

chr6_+_88724462 0.307 ENSMUST00000113582.1
Mgll
monoglyceride lipase
chr18_+_35553401 0.303 ENSMUST00000181664.1
Snhg4
small nucleolar RNA host gene 4 (non-protein coding)
chr11_-_72489904 0.299 ENSMUST00000045303.3
Spns2
spinster homolog 2
chr5_-_144965793 0.294 ENSMUST00000110677.1
ENSMUST00000085684.4
ENSMUST00000100461.2
Smurf1


SMAD specific E3 ubiquitin protein ligase 1


chr5_+_110653444 0.294 ENSMUST00000031478.5
Ddx51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr14_-_6287250 0.292 ENSMUST00000170104.2
Gm3411
predicted gene 3411
chr8_+_104591464 0.290 ENSMUST00000059588.6
Pdp2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr2_+_30807826 0.289 ENSMUST00000041830.3
ENSMUST00000152374.1
Ntmt1

N-terminal Xaa-Pro-Lys N-methyltransferase 1

chr2_-_27426992 0.289 ENSMUST00000056176.7
Vav2
vav 2 oncogene
chr8_+_64947177 0.287 ENSMUST00000079896.7
ENSMUST00000026595.5
Tmem192

transmembrane protein 192

chr13_+_38345716 0.278 ENSMUST00000171970.1
Bmp6
bone morphogenetic protein 6
chr1_+_63176818 0.277 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr1_+_16665189 0.268 ENSMUST00000177501.1
ENSMUST00000065373.5
Tmem70

transmembrane protein 70

chr15_+_89453913 0.263 ENSMUST00000023291.5
Mapk8ip2
mitogen-activated protein kinase 8 interacting protein 2
chr5_-_149051604 0.255 ENSMUST00000093196.4
Hmgb1
high mobility group box 1
chr13_-_71963713 0.254 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr11_-_115491796 0.254 ENSMUST00000106530.1
ENSMUST00000021082.6
Nt5c

5',3'-nucleotidase, cytosolic

chr11_+_60537978 0.250 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chrX_+_135993820 0.246 ENSMUST00000058119.7
Arxes2
adipocyte-related X-chromosome expressed sequence 2
chr14_+_4334763 0.245 ENSMUST00000165466.1
2610042L04Rik
RIKEN cDNA 2610042L04 gene
chr4_-_11386757 0.244 ENSMUST00000108313.1
ENSMUST00000108311.2
Esrp1

epithelial splicing regulatory protein 1

chr7_-_100371889 0.239 ENSMUST00000032963.8
Ppme1
protein phosphatase methylesterase 1
chr18_+_74442500 0.238 ENSMUST00000074157.6
Myo5b
myosin VB
chr13_+_90923122 0.236 ENSMUST00000051955.7
Rps23
ribosomal protein S23
chr12_+_105032638 0.234 ENSMUST00000021522.3
Glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr11_+_87127267 0.231 ENSMUST00000139532.1
Trim37
tripartite motif-containing 37
chr4_+_152325831 0.228 ENSMUST00000103191.4
ENSMUST00000139685.1
Rpl22

ribosomal protein L22

chr8_-_124949165 0.227 ENSMUST00000034469.5
Egln1
EGL nine homolog 1 (C. elegans)
chr3_-_101110278 0.227 ENSMUST00000102694.3
Ptgfrn
prostaglandin F2 receptor negative regulator
chr6_+_49073795 0.226 ENSMUST00000128616.1
ENSMUST00000031839.6
ENSMUST00000114500.1
Malsu1


mitochondrial assembly of ribosomal large subunit 1


chr5_-_149051300 0.219 ENSMUST00000110505.1
Hmgb1
high mobility group box 1
chr14_+_3572023 0.212 ENSMUST00000178728.1
Gm3005
predicted gene 3005
chr9_-_110654161 0.210 ENSMUST00000133191.1
ENSMUST00000167320.1
Nbeal2

neurobeachin-like 2

chr2_+_27515157 0.210 ENSMUST00000113952.3
Wdr5
WD repeat domain 5
chr3_-_58692391 0.207 ENSMUST00000070368.7
Siah2
seven in absentia 2
chr10_+_75893398 0.201 ENSMUST00000009236.4
Derl3
Der1-like domain family, member 3
chr6_+_85451488 0.201 ENSMUST00000032078.6
Cct7
chaperonin containing Tcp1, subunit 7 (eta)
chr14_-_19585135 0.199 ENSMUST00000170694.1
Gm2237
predicted gene 2237
chr10_+_36974536 0.198 ENSMUST00000019911.7
Hdac2
histone deacetylase 2
chr14_-_21052420 0.194 ENSMUST00000154460.1
Ap3m1
adaptor-related protein complex 3, mu 1 subunit
chr14_+_3332627 0.192 ENSMUST00000177786.1
Gm2956
predicted gene 2956
chr15_-_93336800 0.191 ENSMUST00000080299.6
Yaf2
YY1 associated factor 2
chr17_-_46752170 0.189 ENSMUST00000121671.1
ENSMUST00000059844.6
Cnpy3

canopy 3 homolog (zebrafish)

chr18_+_52465676 0.189 ENSMUST00000025406.7
Srfbp1
serum response factor binding protein 1
chrX_+_10717451 0.188 ENSMUST00000156321.1
Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr2_+_180119301 0.187 ENSMUST00000040668.8
Osbpl2
oxysterol binding protein-like 2
chr6_+_88724412 0.184 ENSMUST00000113585.2
Mgll
monoglyceride lipase
chrX_+_10717390 0.177 ENSMUST00000115524.1
ENSMUST00000008179.6
Mid1ip1

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

chr5_+_100039990 0.175 ENSMUST00000169390.1
ENSMUST00000031268.6
Enoph1

enolase-phosphatase 1

chr7_+_3704025 0.166 ENSMUST00000108623.1
ENSMUST00000139818.1
ENSMUST00000108625.1
Rps9


ribosomal protein S9


chr11_+_117115133 0.166 ENSMUST00000021177.8
Sec14l1
SEC14-like 1 (S. cerevisiae)
chr16_+_20498817 0.165 ENSMUST00000003320.6
Eif2b5
eukaryotic translation initiation factor 2B, subunit 5 epsilon
chr10_-_13193096 0.162 ENSMUST00000019950.4
Ltv1
LTV1 homolog (S. cerevisiae)
chr7_+_122067164 0.158 ENSMUST00000033158.4
Ubfd1
ubiquitin family domain containing 1
chr2_+_121140498 0.157 ENSMUST00000119031.1
ENSMUST00000110662.2
Adal

adenosine deaminase-like

chr19_-_6921753 0.156 ENSMUST00000173635.1
Esrra
estrogen related receptor, alpha
chr10_+_36974558 0.154 ENSMUST00000105510.1
Hdac2
histone deacetylase 2
chr14_-_29721835 0.154 ENSMUST00000022567.7
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr4_-_133967953 0.153 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr4_-_62519885 0.152 ENSMUST00000107444.1
ENSMUST00000030090.3
Alad

aminolevulinate, delta-, dehydratase

chr10_-_127180579 0.149 ENSMUST00000095270.2
Slc26a10
solute carrier family 26, member 10
chr11_+_87127052 0.147 ENSMUST00000041282.6
Trim37
tripartite motif-containing 37
chr5_+_146948640 0.141 ENSMUST00000146511.1
ENSMUST00000132102.1
Gtf3a

general transcription factor III A

chr7_-_44986313 0.140 ENSMUST00000045325.6
ENSMUST00000085387.4
ENSMUST00000107840.1
ENSMUST00000107843.3
ENSMUST00000107842.3
Prmt1




protein arginine N-methyltransferase 1




chr15_-_75909289 0.139 ENSMUST00000145764.1
ENSMUST00000116440.2
ENSMUST00000151066.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr14_-_70443219 0.139 ENSMUST00000180358.1
Polr3d
polymerase (RNA) III (DNA directed) polypeptide D
chr15_+_102203639 0.136 ENSMUST00000118729.1
ENSMUST00000119168.1
ENSMUST00000141465.1
ENSMUST00000139960.1
Zfp740



zinc finger protein 740



chr4_+_131873608 0.133 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr13_+_118714678 0.132 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr8_-_69974367 0.132 ENSMUST00000116463.2
Gatad2a
GATA zinc finger domain containing 2A
chr6_-_85451248 0.132 ENSMUST00000113770.1
ENSMUST00000032080.2
Pradc1

protease-associated domain containing 1

chr14_+_4726775 0.127 ENSMUST00000165619.1
Gm3252
predicted gene 3252
chr7_+_105736702 0.124 ENSMUST00000163389.1
ENSMUST00000136687.1
Ilk

integrin linked kinase

chr19_-_45006385 0.113 ENSMUST00000097715.2
Mrpl43
mitochondrial ribosomal protein L43
chr7_+_105736565 0.111 ENSMUST00000033182.3
Ilk
integrin linked kinase
chr7_+_16310412 0.110 ENSMUST00000136781.1
Bbc3
BCL2 binding component 3
chr4_-_143212691 0.105 ENSMUST00000105778.1
ENSMUST00000134791.1
Prdm2

PR domain containing 2, with ZNF domain

chr18_+_65581704 0.104 ENSMUST00000182979.1
Zfp532
zinc finger protein 532
chr8_-_116993459 0.103 ENSMUST00000040484.5
Gcsh
glycine cleavage system protein H (aminomethyl carrier)
chr14_-_6889962 0.103 ENSMUST00000171906.1
Gm3667
predicted gene 3667
chr14_+_33319703 0.102 ENSMUST00000111955.1
Arhgap22
Rho GTPase activating protein 22
chr9_+_108347827 0.101 ENSMUST00000035237.6
Usp4
ubiquitin specific peptidase 4 (proto-oncogene)
chr2_+_68861433 0.101 ENSMUST00000028426.2
Cers6
ceramide synthase 6
chr4_-_139352298 0.099 ENSMUST00000030513.6
ENSMUST00000155257.1
Mrto4

MRT4, mRNA turnover 4, homolog (S. cerevisiae)

chr11_+_68692070 0.096 ENSMUST00000108673.1
Myh10
myosin, heavy polypeptide 10, non-muscle
chr6_+_108828633 0.095 ENSMUST00000089162.3
Edem1
ER degradation enhancer, mannosidase alpha-like 1
chr2_-_121140649 0.092 ENSMUST00000110674.2
Lcmt2
leucine carboxyl methyltransferase 2
chr14_+_3652030 0.091 ENSMUST00000167430.1
Gm3020
predicted gene 3020
chr5_+_124112297 0.090 ENSMUST00000024470.6
ENSMUST00000119269.1
Ogfod2

2-oxoglutarate and iron-dependent oxygenase domain containing 2

chr7_-_109752210 0.088 ENSMUST00000128043.1
ENSMUST00000033333.6
Tmem9b

TMEM9 domain family, member B

chr16_-_24393588 0.088 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr13_+_73604002 0.087 ENSMUST00000022102.7
Clptm1l
CLPTM1-like
chr17_-_45573253 0.087 ENSMUST00000165127.1
ENSMUST00000166469.1
ENSMUST00000024739.7
Hsp90ab1


heat shock protein 90 alpha (cytosolic), class B member 1


chr2_-_148875452 0.084 ENSMUST00000028938.6
ENSMUST00000144845.1
Cst3

cystatin C

chrX_+_143518576 0.084 ENSMUST00000033640.7
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr5_+_135168283 0.082 ENSMUST00000031692.5
Bcl7b
B cell CLL/lymphoma 7B
chr4_-_139352538 0.080 ENSMUST00000102503.3
Mrto4
MRT4, mRNA turnover 4, homolog (S. cerevisiae)
chr3_-_95882232 0.077 ENSMUST00000161866.1
Gm129
predicted gene 129
chr10_+_122678764 0.071 ENSMUST00000161487.1
ENSMUST00000067918.5
Ppm1h

protein phosphatase 1H (PP2C domain containing)

chr1_-_180256294 0.066 ENSMUST00000111108.3
Psen2
presenilin 2
chrX_-_20950597 0.064 ENSMUST00000009550.7
Elk1
ELK1, member of ETS oncogene family
chr1_-_161251153 0.062 ENSMUST00000051925.4
ENSMUST00000071718.5
Prdx6

peroxiredoxin 6

chr1_+_120602405 0.062 ENSMUST00000079721.7
En1
engrailed 1
chr14_-_70443442 0.060 ENSMUST00000000793.5
Polr3d
polymerase (RNA) III (DNA directed) polypeptide D
chr3_-_9004472 0.058 ENSMUST00000091355.5
ENSMUST00000134788.1
Tpd52

tumor protein D52

chr2_-_121140371 0.055 ENSMUST00000099486.2
Lcmt2
leucine carboxyl methyltransferase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0019659 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.3 1.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.3 2.3 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.3 0.8 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.3 0.8 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.3 1.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 1.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 0.2 GO:0033122 regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.2 1.8 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 1.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.6 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.2 0.6 GO:0007621 negative regulation of female receptivity(GO:0007621) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of cellular pH reduction(GO:0032847) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2 2.0 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 0.7 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.2 1.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 0.5 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.2 0.5 GO:0010248 B cell negative selection(GO:0002352) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 1.0 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.6 GO:0042117 hyaluronan catabolic process(GO:0030214) monocyte activation(GO:0042117)
0.1 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.2 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 0.4 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.3 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.2 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 0.4 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.1 0.2 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.1 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.3 GO:0046958 nonassociative learning(GO:0046958)
0.1 0.3 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.6 GO:0030388 fructose 6-phosphate metabolic process(GO:0006002) fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.2 GO:0032439 endosome localization(GO:0032439)
0.1 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579) single-organism membrane invagination(GO:1902534)
0.1 0.3 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.1 0.4 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.1 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 2.0 GO:0045214 sarcomere organization(GO:0045214)
0.1 1.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.6 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812) negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.3 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.0 0.4 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:0071336 lung growth(GO:0060437) positive regulation of fat cell proliferation(GO:0070346) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.6 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.4 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.7 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.7 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0 0.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.2 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.0 0.4 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.4 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.2 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) response to cobalt ion(GO:0032025)
0.0 0.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.4 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.5 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.7 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.2 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 1.7 GO:0071229 cellular response to acid chemical(GO:0071229)
0.0 0.2 GO:0045663 negative regulation of cardiac muscle cell apoptotic process(GO:0010667) positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0008272 sulfate transport(GO:0008272)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.2 0.5 GO:0034455 t-UTP complex(GO:0034455)
0.2 1.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 1.2 GO:0097452 GAIT complex(GO:0097452)
0.1 0.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 1.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.5 GO:0043196 varicosity(GO:0043196)
0.1 0.8 GO:0005883 neurofilament(GO:0005883)
0.1 0.7 GO:0097433 dense body(GO:0097433)
0.1 0.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 2.2 GO:0043034 costamere(GO:0043034)
0.1 0.7 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 1.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0048188 MLL3/4 complex(GO:0044666) Set1C/COMPASS complex(GO:0048188)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 1.2 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.3 1.8 GO:0042296 ISG15 transferase activity(GO:0042296)
0.3 1.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 1.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.6 GO:0030292 hyalurononglucosaminidase activity(GO:0004415) protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 0.5 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.2 0.6 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 0.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 1.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.6 GO:0070883 importin-alpha family protein binding(GO:0061676) pre-miRNA binding(GO:0070883)
0.1 1.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.8 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.4 GO:0035851 histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851)
0.1 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 2.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0030519 snoRNP binding(GO:0030519)
0.0 0.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 1.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 2.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0034547 GTP cyclohydrolase activity(GO:0003933) N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0051723 protein methylesterase activity(GO:0051723)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.7 GO:0019955 cytokine binding(GO:0019955)