Motif ID: Hlf

Z-value: 0.618


Transcription factors associated with Hlf:

Gene SymbolEntrez IDGene Name
Hlf ENSMUSG00000003949.10 Hlf

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hlfmm10_v2_chr11_-_90390895_90390926-0.352.2e-01Click!


Activity profile for motif Hlf.

activity profile for motif Hlf


Sorted Z-values histogram for motif Hlf

Sorted Z-values for motif Hlf



Network of associatons between targets according to the STRING database.



First level regulatory network of Hlf

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_30413744 1.335 ENSMUST00000032800.9
Tyrobp
TYRO protein tyrosine kinase binding protein
chr6_+_17463749 1.051 ENSMUST00000115443.1
Met
met proto-oncogene
chr5_-_3473178 0.944 ENSMUST00000168422.1
Gm17590
predicted gene, 17590
chr15_-_88978958 0.901 ENSMUST00000042594.6
ENSMUST00000109368.1
Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr1_-_140183404 0.879 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr11_-_101785252 0.877 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr7_-_42578588 0.813 ENSMUST00000179470.1
Gm21028
predicted gene, 21028
chr18_-_36726730 0.677 ENSMUST00000061829.6
Cd14
CD14 antigen
chr10_-_31445921 0.641 ENSMUST00000000305.5
Tpd52l1
tumor protein D52-like 1
chr8_-_92355764 0.616 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
4933436C20Rik



RIKEN cDNA 4933436C20 gene



chr1_-_140183283 0.588 ENSMUST00000111977.1
Cfh
complement component factor h
chr9_+_94669876 0.587 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr19_-_50678642 0.569 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr4_+_42735545 0.524 ENSMUST00000068158.3
4930578G10Rik
RIKEN cDNA 4930578G10 gene
chr9_-_77347816 0.521 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chr9_-_77347787 0.512 ENSMUST00000184848.1
ENSMUST00000184415.1
Mlip

muscular LMNA-interacting protein

chr3_+_84952146 0.499 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr9_-_21037775 0.496 ENSMUST00000180870.1
Gm26592
predicted gene, 26592
chr7_+_18884679 0.493 ENSMUST00000032573.6
Pglyrp1
peptidoglycan recognition protein 1
chr9_-_77347889 0.477 ENSMUST00000185039.1
Mlip
muscular LMNA-interacting protein
chr3_+_66219909 0.467 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr14_+_50944499 0.409 ENSMUST00000178092.1
Pnp
purine-nucleoside phosphorylase
chr4_+_150237694 0.389 ENSMUST00000141931.1
Eno1
enolase 1, alpha non-neuron
chr4_-_42856771 0.384 ENSMUST00000107981.1
Gm12394
predicted gene 12394
chrX_+_73064787 0.363 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr10_+_78574492 0.348 ENSMUST00000105384.3
Ilvbl
ilvB (bacterial acetolactate synthase)-like
chr2_+_25180737 0.347 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr14_+_65971049 0.341 ENSMUST00000128539.1
Clu
clusterin
chr16_+_92292380 0.338 ENSMUST00000047383.3
Kcne2
potassium voltage-gated channel, Isk-related subfamily, gene 2
chr17_-_31637135 0.337 ENSMUST00000118504.1
ENSMUST00000078509.5
ENSMUST00000067801.6
Cbs


cystathionine beta-synthase


chr1_+_156838915 0.320 ENSMUST00000111720.1
Angptl1
angiopoietin-like 1
chr8_-_92356103 0.320 ENSMUST00000034183.3
4933436C20Rik
RIKEN cDNA 4933436C20 gene
chr3_-_80913528 0.315 ENSMUST00000107743.1
ENSMUST00000029654.8
Glrb

glycine receptor, beta subunit

chr3_-_127553233 0.308 ENSMUST00000029588.5
Larp7
La ribonucleoprotein domain family, member 7
chr17_-_47691403 0.303 ENSMUST00000113299.1
ENSMUST00000152214.1
Gm21981
Prickle4
predicted gene 21981
prickle homolog 4 (Drosophila)
chr2_-_109280718 0.295 ENSMUST00000147770.1
Mettl15
methyltransferase like 15
chr10_-_70592782 0.291 ENSMUST00000162251.1
Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chr3_+_86070915 0.290 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr17_+_32284772 0.287 ENSMUST00000181112.1
Gm26549
predicted gene, 26549
chr4_+_41942037 0.285 ENSMUST00000181518.1
Gm20878
predicted gene, 20878
chr12_+_117843489 0.285 ENSMUST00000021592.9
Cdca7l
cell division cycle associated 7 like
chr16_+_78930940 0.282 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
Chodl


chondrolectin


chr16_-_59555752 0.281 ENSMUST00000179383.1
ENSMUST00000044604.8
Crybg3

beta-gamma crystallin domain containing 3

chr14_+_65971164 0.276 ENSMUST00000144619.1
Clu
clusterin
chr5_+_135009152 0.272 ENSMUST00000111216.1
ENSMUST00000046999.8
Abhd11

abhydrolase domain containing 11

chr14_+_65970804 0.269 ENSMUST00000138191.1
Clu
clusterin
chr2_+_155751117 0.267 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr5_-_147894804 0.256 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
Slc46a3


solute carrier family 46, member 3


chr9_-_107668967 0.253 ENSMUST00000177567.1
Slc38a3
solute carrier family 38, member 3
chr8_+_46471041 0.252 ENSMUST00000034046.5
Acsl1
acyl-CoA synthetase long-chain family member 1
chr1_+_107511416 0.249 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr16_+_36041184 0.246 ENSMUST00000042203.8
Wdr5b
WD repeat domain 5B
chr11_+_83662579 0.245 ENSMUST00000019074.3
Ccl4
chemokine (C-C motif) ligand 4
chr18_-_35498856 0.243 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr15_+_99074968 0.240 ENSMUST00000039665.6
Troap
trophinin associated protein
chr16_+_43510267 0.236 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chr2_-_129371131 0.233 ENSMUST00000028881.7
Il1b
interleukin 1 beta
chr7_+_110774240 0.233 ENSMUST00000147587.1
Ampd3
adenosine monophosphate deaminase 3
chr10_-_62507737 0.227 ENSMUST00000020271.6
Srgn
serglycin
chr16_-_57606816 0.226 ENSMUST00000114371.3
Cmss1
cms small ribosomal subunit 1
chrX_-_162565514 0.222 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr18_+_37484955 0.220 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr14_+_50955992 0.219 ENSMUST00000095925.4
Pnp2
purine-nucleoside phosphorylase 2
chr2_+_155940728 0.216 ENSMUST00000109629.1
Gm15557
predicted gene 15557
chr1_-_165236892 0.191 ENSMUST00000043235.5
Tiprl
TIP41, TOR signalling pathway regulator-like (S. cerevisiae)
chr14_-_18893376 0.190 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr7_-_13034722 0.185 ENSMUST00000005711.4
Chmp2a
charged multivesicular body protein 2A
chr5_+_66968961 0.182 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr18_+_50030977 0.182 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr6_-_83033422 0.181 ENSMUST00000089651.5
Dok1
docking protein 1
chr4_+_41941572 0.179 ENSMUST00000108028.2
ENSMUST00000153997.1
Gm20878

predicted gene, 20878

chr2_+_132847719 0.178 ENSMUST00000124836.1
ENSMUST00000154160.1
Crls1

cardiolipin synthase 1

chr7_+_138846579 0.177 ENSMUST00000155672.1
Ppp2r2d
protein phosphatase 2, regulatory subunit B, delta isoform
chr3_+_51559757 0.176 ENSMUST00000180616.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chr15_-_101850778 0.175 ENSMUST00000023790.3
Krt1
keratin 1
chr8_-_33929798 0.175 ENSMUST00000033995.7
ENSMUST00000033994.8
ENSMUST00000053251.5
Rbpms


RNA binding protein gene with multiple splicing


chr17_-_24073479 0.175 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr12_+_105563123 0.174 ENSMUST00000001652.5
Bdkrb2
bradykinin receptor, beta 2
chr7_+_110773658 0.173 ENSMUST00000143786.1
Ampd3
adenosine monophosphate deaminase 3
chr7_+_138846335 0.171 ENSMUST00000041097.6
Ppp2r2d
protein phosphatase 2, regulatory subunit B, delta isoform
chr2_+_164879358 0.170 ENSMUST00000041643.3
Pcif1
PDX1 C-terminal inhibiting factor 1
chr17_+_43801823 0.170 ENSMUST00000044895.5
Rcan2
regulator of calcineurin 2
chr12_+_73286779 0.163 ENSMUST00000140523.1
Slc38a6
solute carrier family 38, member 6
chr5_-_122988533 0.162 ENSMUST00000086200.4
ENSMUST00000156474.1
Kdm2b

lysine (K)-specific demethylase 2B

chr17_-_45592569 0.158 ENSMUST00000163492.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr4_-_42084291 0.155 ENSMUST00000177937.1
Gm21968
predicted gene, 21968
chr16_-_4790220 0.153 ENSMUST00000118703.1
Cdip1
cell death inducing Trp53 target 1
chr15_-_37007382 0.148 ENSMUST00000078976.7
Zfp706
zinc finger protein 706
chr9_+_115909455 0.147 ENSMUST00000119291.1
ENSMUST00000069651.6
Gadl1

glutamate decarboxylase-like 1

chr6_+_90465287 0.146 ENSMUST00000113530.1
Klf15
Kruppel-like factor 15
chr12_-_104865076 0.145 ENSMUST00000109937.1
ENSMUST00000109936.1
Clmn

calmin

chr17_-_14694223 0.143 ENSMUST00000170872.1
Thbs2
thrombospondin 2
chr18_-_80713062 0.143 ENSMUST00000170905.1
ENSMUST00000078049.4
Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr9_+_64179289 0.142 ENSMUST00000034965.6
Snapc5
small nuclear RNA activating complex, polypeptide 5
chr2_-_132111440 0.138 ENSMUST00000128899.1
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr5_-_5514730 0.137 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12



claudin 12



chr2_+_181497223 0.136 ENSMUST00000108799.3
Tpd52l2
tumor protein D52-like 2
chr19_-_53371766 0.135 ENSMUST00000086887.1
Gm10197
predicted gene 10197
chr17_-_45592485 0.135 ENSMUST00000166119.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr4_-_119538769 0.134 ENSMUST00000079611.6
AA415398
expressed sequence AA415398
chr12_-_69159109 0.133 ENSMUST00000037023.8
Rps29
ribosomal protein S29
chr9_+_106170918 0.133 ENSMUST00000020490.5
Wdr82
WD repeat domain containing 82
chr16_-_4789887 0.131 ENSMUST00000117713.1
Cdip1
cell death inducing Trp53 target 1
chr11_-_69980468 0.129 ENSMUST00000143175.1
Elp5
elongator acetyltransferase complex subunit 5
chr13_+_93771656 0.129 ENSMUST00000091403.4
Arsb
arylsulfatase B
chr8_+_3621529 0.127 ENSMUST00000156380.2
Pet100
PET100 homolog (S. cerevisiae)
chrX_-_155216338 0.127 ENSMUST00000112551.3
Sat1
spermidine/spermine N1-acetyl transferase 1
chr16_-_4789984 0.126 ENSMUST00000004173.5
Cdip1
cell death inducing Trp53 target 1
chr14_+_78849171 0.123 ENSMUST00000040990.5
Vwa8
von Willebrand factor A domain containing 8
chr1_+_107511489 0.122 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr11_+_6415443 0.115 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr17_+_28691342 0.114 ENSMUST00000114758.1
ENSMUST00000004990.6
ENSMUST00000062694.8
ENSMUST00000114754.1
Mapk14



mitogen-activated protein kinase 14



chr14_+_26122609 0.114 ENSMUST00000100810.6
Duxbl2
doubl homeobox B-like 2
chr8_-_4275886 0.112 ENSMUST00000003029.7
Timm44
translocase of inner mitochondrial membrane 44
chr15_+_92597104 0.111 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr10_-_17947997 0.109 ENSMUST00000037879.6
Heca
headcase homolog (Drosophila)
chr15_-_98728120 0.108 ENSMUST00000003445.6
Fkbp11
FK506 binding protein 11
chr13_+_49504774 0.108 ENSMUST00000051504.7
Ecm2
extracellular matrix protein 2, female organ and adipocyte specific
chr4_-_98817537 0.103 ENSMUST00000102790.3
Kank4
KN motif and ankyrin repeat domains 4
chr4_-_11981265 0.102 ENSMUST00000098260.2
Gm10604
predicted gene 10604
chr6_-_128424883 0.101 ENSMUST00000001559.8
Itfg2
integrin alpha FG-GAP repeat containing 2
chr17_+_25809085 0.099 ENSMUST00000045692.7
Fbxl16
F-box and leucine-rich repeat protein 16
chr10_+_80141457 0.098 ENSMUST00000105367.1
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr10_+_22645011 0.097 ENSMUST00000042261.4
Slc2a12
solute carrier family 2 (facilitated glucose transporter), member 12
chr7_-_44496406 0.097 ENSMUST00000118515.1
ENSMUST00000138328.1
ENSMUST00000008284.8
ENSMUST00000118808.1
Emc10



ER membrane protein complex subunit 10



chr7_+_44468051 0.095 ENSMUST00000118493.1
Josd2
Josephin domain containing 2
chr14_+_70577839 0.095 ENSMUST00000089049.2
Nudt18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr7_-_138846202 0.095 ENSMUST00000118810.1
ENSMUST00000075667.4
ENSMUST00000119664.1
Mapk1ip1


mitogen-activated protein kinase 1 interacting protein 1


chr7_-_46667375 0.094 ENSMUST00000107669.2
Tph1
tryptophan hydroxylase 1
chr10_+_88731056 0.094 ENSMUST00000116234.2
Arl1
ADP-ribosylation factor-like 1
chr4_-_89311021 0.089 ENSMUST00000097981.4
Cdkn2b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr17_+_47737030 0.089 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr15_+_34238026 0.086 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr17_+_28691419 0.081 ENSMUST00000124886.1
Mapk14
mitogen-activated protein kinase 14
chr19_-_24961545 0.080 ENSMUST00000025815.8
Cbwd1
COBW domain containing 1
chrX_-_155216444 0.080 ENSMUST00000026318.8
Sat1
spermidine/spermine N1-acetyl transferase 1
chr18_+_37320374 0.079 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr1_+_134455524 0.077 ENSMUST00000112232.1
ENSMUST00000027725.4
ENSMUST00000116528.1
Klhl12


kelch-like 12


chr2_-_38644087 0.075 ENSMUST00000028083.5
Psmb7
proteasome (prosome, macropain) subunit, beta type 7
chr11_+_79660532 0.075 ENSMUST00000155381.1
Rab11fip4
RAB11 family interacting protein 4 (class II)
chr10_+_96616998 0.075 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr2_-_130642770 0.074 ENSMUST00000045761.6
Lzts3
leucine zipper, putative tumor suppressor family member 3
chr6_-_13838432 0.073 ENSMUST00000115492.1
Gpr85
G protein-coupled receptor 85
chr8_-_122476036 0.073 ENSMUST00000014614.3
Rnf166
ring finger protein 166
chr2_+_69670100 0.071 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr2_-_86347764 0.070 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr6_-_97459279 0.069 ENSMUST00000113359.1
Frmd4b
FERM domain containing 4B
chr8_-_3621270 0.069 ENSMUST00000159548.1
ENSMUST00000019614.6
Xab2

XPA binding protein 2

chr4_+_152039315 0.069 ENSMUST00000084116.6
ENSMUST00000105663.1
ENSMUST00000103197.3
Nol9


nucleolar protein 9


chr4_+_47208005 0.067 ENSMUST00000082303.6
ENSMUST00000102917.4
Col15a1

collagen, type XV, alpha 1

chr5_-_5514873 0.064 ENSMUST00000060947.7
Cldn12
claudin 12
chr3_+_89459118 0.063 ENSMUST00000029564.5
Pmvk
phosphomevalonate kinase
chr8_+_105636509 0.062 ENSMUST00000005841.9
Ctcf
CCCTC-binding factor
chr14_-_32085595 0.062 ENSMUST00000022461.4
ENSMUST00000067955.5
ENSMUST00000124303.1
ENSMUST00000112000.1
Dph3



diphthamine biosynthesis 3



chr4_+_147868830 0.061 ENSMUST00000094481.1
Fv1
Friend virus susceptibility 1
chr18_+_23803962 0.061 ENSMUST00000025127.3
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr1_+_10993452 0.060 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr2_-_120609319 0.058 ENSMUST00000102497.3
Lrrc57
leucine rich repeat containing 57
chr10_+_127420867 0.057 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chr19_+_4756557 0.057 ENSMUST00000036744.7
Rbm4b
RNA binding motif protein 4B
chr4_+_146654927 0.055 ENSMUST00000070932.3
Gm13248
predicted gene 13248
chr10_-_111997204 0.055 ENSMUST00000074805.5
Glipr1
GLI pathogenesis-related 1 (glioma)
chr17_-_26508463 0.054 ENSMUST00000025025.6
Dusp1
dual specificity phosphatase 1
chr2_+_132690120 0.053 ENSMUST00000148271.1
ENSMUST00000110132.2
1110034G24Rik

RIKEN cDNA 1110034G24 gene

chr13_+_51100810 0.053 ENSMUST00000095797.5
Spin1
spindlin 1
chr6_-_23248264 0.053 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr6_-_86669136 0.052 ENSMUST00000001184.7
Mxd1
MAX dimerization protein 1
chr1_-_91459254 0.052 ENSMUST00000069620.8
Per2
period circadian clock 2
chr7_+_19228334 0.052 ENSMUST00000063976.8
Opa3
optic atrophy 3
chr12_+_72761211 0.052 ENSMUST00000021514.8
Ppm1a
protein phosphatase 1A, magnesium dependent, alpha isoform
chr10_+_121739915 0.052 ENSMUST00000065600.7
ENSMUST00000136432.1
BC048403

cDNA sequence BC048403

chr19_+_43752996 0.052 ENSMUST00000026199.7
ENSMUST00000112047.3
ENSMUST00000153295.1
Cutc


cutC copper transporter homolog (E.coli)


chr1_-_38129618 0.051 ENSMUST00000027251.6
Rev1
REV1 homolog (S. cerevisiae)
chr2_+_181497165 0.049 ENSMUST00000149163.1
ENSMUST00000000844.8
ENSMUST00000184849.1
ENSMUST00000108800.1
ENSMUST00000069712.2
Tpd52l2




tumor protein D52-like 2




chr2_+_120609383 0.048 ENSMUST00000124187.1
Haus2
HAUS augmin-like complex, subunit 2
chr11_+_69323963 0.047 ENSMUST00000102602.1
Trappc1
trafficking protein particle complex 1
chr6_+_83034173 0.047 ENSMUST00000000707.2
ENSMUST00000101257.3
Loxl3

lysyl oxidase-like 3

chr16_+_91391721 0.047 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr17_+_84511832 0.046 ENSMUST00000047206.5
Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr15_+_99393574 0.046 ENSMUST00000162624.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr15_+_99393610 0.045 ENSMUST00000159531.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr7_+_27447978 0.045 ENSMUST00000037399.9
ENSMUST00000108358.1
Blvrb

biliverdin reductase B (flavin reductase (NADPH))

chr1_+_180641330 0.044 ENSMUST00000085804.5
Lin9
lin-9 homolog (C. elegans)
chr4_+_55350043 0.042 ENSMUST00000030134.8
Rad23b
RAD23b homolog (S. cerevisiae)
chr11_+_69324055 0.042 ENSMUST00000102601.3
Trappc1
trafficking protein particle complex 1
chr2_-_120609500 0.041 ENSMUST00000133612.1
ENSMUST00000102498.1
ENSMUST00000102499.1
Lrrc57


leucine rich repeat containing 57


chr11_-_116086929 0.039 ENSMUST00000074628.6
ENSMUST00000106444.3
Wbp2

WW domain binding protein 2

chr11_+_69324069 0.038 ENSMUST00000060956.6
ENSMUST00000108662.1
Trappc1

trafficking protein particle complex 1

chr12_+_86421628 0.038 ENSMUST00000110203.1
ENSMUST00000110204.2
Esrrb

estrogen related receptor, beta

chr14_-_59597836 0.036 ENSMUST00000167100.1
ENSMUST00000022555.4
ENSMUST00000056997.7
ENSMUST00000171683.1
Cdadc1



cytidine and dCMP deaminase domain containing 1



chr7_-_4149781 0.036 ENSMUST00000058358.6
Leng9
leukocyte receptor cluster (LRC) member 9
chr4_+_41348996 0.035 ENSMUST00000072866.5
ENSMUST00000108060.3
Ubap1

ubiquitin-associated protein 1

chr2_+_3513035 0.035 ENSMUST00000036350.2
Cdnf
cerebral dopamine neurotrophic factor
chr12_+_24651346 0.034 ENSMUST00000020982.5
Klf11
Kruppel-like factor 11
chr8_-_91133942 0.033 ENSMUST00000120213.1
ENSMUST00000109609.2
Aktip

thymoma viral proto-oncogene 1 interacting protein

chr3_+_40800054 0.032 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chr12_-_73286698 0.031 ENSMUST00000116420.2
Trmt5
TRM5 tRNA methyltransferase 5
chr2_-_120609283 0.030 ENSMUST00000102496.1
Lrrc57
leucine rich repeat containing 57
chr11_-_6444352 0.029 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv

H2A histone family, member V

chr10_+_20347788 0.027 ENSMUST00000169712.1
Mtfr2
mitochondrial fission regulator 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:2001204 regulation of osteoclast development(GO:2001204)
0.2 1.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.2 0.7 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.2 0.5 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.9 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.1 0.9 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1 0.4 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 1.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.3 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.1 0.3 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.1 0.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.5 GO:0098543 detection of bacterium(GO:0016045) negative regulation of natural killer cell activation(GO:0032815) detection of other organism(GO:0098543)
0.1 0.2 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 0.2 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.2 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 1.5 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 0.3 GO:0006867 asparagine transport(GO:0006867) glutamine transport(GO:0006868)
0.1 0.2 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 0.6 GO:0043101 purine-containing compound salvage(GO:0043101)
0.1 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.3 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043) positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0060854 patterning of lymph vessels(GO:0060854)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.3 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.3 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.3 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.2 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.0 0.1 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.1 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.0 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.0 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.0 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.1 0.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.3 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.5 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0031091 platelet alpha granule(GO:0031091)
0.0 0.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 1.5 GO:0055037 recycling endosome(GO:0055037)
0.0 0.0 GO:0071942 XPC complex(GO:0071942)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0001851 complement component C3b binding(GO:0001851)
0.3 1.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 0.5 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 0.6 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 0.7 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.3 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.5 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.5 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.3 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 0.6 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.9 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.0 0.0 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.0 0.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.3 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.0 GO:0004074 biliverdin reductase activity(GO:0004074)